Amlodipine alakaʻi

Medicine "Amlodipine" paha kama'āina i ka nui mua-lima. Holo nōhie, keia k ua kuhikuhi i nā mea maʻi angina. E mākou noonoo i ka lāʻau "Amlodipine" kona kuhikuhi pihaʻi me na kēia 'ikepili.

Haku mele 'ana. Kekahi papa (5 mg) i pihaʻi me na hana waiwai amlodipine besylate. Like excipients hoʻohana lactose, uala pia, collidone, microcrystalline kelulose, makanekiuma stearate.

General hōʻikeʻano. "Amlodipine" papa keʻokeʻo a aneane keʻokeʻo me ka mau-kapakahi ami. Kēlā wā i kēia wā malamalama i e ike marbling.

Pharmacodynamics. Dihydropyridine derivative - ālai 'kalipuna "lohi" lua-hanauna auwai a ua gipotezivnoe a me antianginal' ole. Pili me ka dihydropyridine mea loaʻa a me ka hāpai blockade o ke kalipuna auwai a, hiki hoemi i ka transmembrane e hooholo ia ana o kalipuna Ion i loko o ka halepaahao (a hiki i ka nui loa i loko o nāʻalā Muscle o ka moku pā ma mua o ka cardiac myocytes). Antianginal ai ua kena ae la ia e? Anoe? O na arteries a me arterioles aia i loko o ka periphery: angina umenshaetsnizhaet oolea o myocardial ischemia,ʻike ākea artery Hoʻonui i ka pono, i laila hoemi ka huina vascularʻike ākea ia'ku, ma ka hou e kokua i ka emi i ka preload ma luna o ka naʻau, ho'ēmi i kā ka pono naʻau o ka oxygen. Ma nā mea maʻi me ka angina, ka mea i kela la hookahi mahele lāʻau maoli ka holo manawa fiznagruzki, 'aʻole hoʻi i ka ulu ana o ka ischemia a me ka angina, hoʻohui pau ho'ēmi i kā ka multiplicity o angina ho'āhewa wale a me ka nele i ka nitroglycerin. Penei, nā mea maʻi me ka angina nele "Amlodipine" alakai keia maopopo.

Pharmacokinetics. Ma hope o moʻolelo hooponopono o ka lāʻau ua mālie ke kemu, mai ka gastrointestinal'āpana. Loa awelike bioavailability o 64%, i ka mea i kia i loko o ke koko ma hope o lāʻau lapaʻau 6-9 hola. Ka pilina paʻa koena i loko o ke koko ua ike i ka 7th lā. Food aʻole e pili mai ka omo o ka amlodipine. I ka poʻeʻelemākule hoʻomanawanui iki mai (mua ma mua o 65 makahiki) i ka excretion o ka lāʻau ua lohi hoʻohālike ai i ke kaikamahine, akā, i kēia like mea,ʻaʻole clinically nui.

"Amlodipine" ke aʻo a iloko ona i kakauia a pau o ka mea 'ike i ka hope o nāʻikepili a hiki i ka noi: ka arterial hypertension (hoʻohui pū' ia me ka 'ē paha i' ano like 'ano monotherapy), exertional angina, vasospastic angina (Prinzmetal ka angina).

Contraindications.

- kiʻekiʻe pā lonoaʻili i kaʻeleu 'Oponopono a me nā dihydropyridine nā mea loaʻa;

- hypotension ma loa ke ano;

- cardiogenic kŰia, 'opi;

- lolelua ka angina (koe nae - Prinzmetal angina);

- lactation a me ka hāpai keiki;

- no ka mea ma lalo o makahiki 18 o ka palekana a me ka ole, i ole, ua hoʻokūpaʻa.

Ka laʻau heluna a me ka papa hana o ka palapala noi. E "Amlodipine" aʻo hoʻolako like penei: loko, ka palena iki mahele lāʻau o 5 mg, ka i kā mākou - 10 mg 1 manawa i ka lā. I ka hypertension mahele lāʻau no ka mālama 'ana i hiki e 5 mg no ka lā. I ka hahau ana ia hookahi 5-10 mg no ka lā. Lahilahi nā mea maʻi, e like me nā mea maʻi haʻahaʻa a me nā mea maʻi me kaʻole ake functioning lawelawe 2,5 mg.

Special ao. I loko o ka papa o ka iapaau ana me "Amlodipine" E hahai i ke kaumaha a me ka hokii, o na waiwai e like me ka paʻakai, i kekahi manawa, he pono ke kupaianahaʻai. He nui no ka hahai i nā moʻolelo kou niho a me ka niho, e kipa i ka dentist mau (e pale aku ka eha, a kahe ana ke koko nui aʻe ana). Ma ka hoʻoulu i ka mahele lāʻau i loko o ka kūpuna koi akahele ka mālamaʻana. Ke kanawai o ka lāʻau ma ka hiki, e kipaku aku i kaʻa mea, aoheʻikepili. Naʻe, ka mea e e kaʻikaʻiʻia ma ka manaʻo i loko o kekahi kanaka ka mea, ke i hōʻemi iki pōniuniu a me ka drowsiness.