"Domidon": aʻo no ka hoʻohana, a me ka mea ia ia no

Me ka ooieoeiiaeuiuo kāna hana o ka digestive'āpanaʻalo a pau. Loa pinepine, discomfort i loko o ka epigastric māhele ai ka haohao ana no ka poʻeʻilihune a me ka kūpono no kou kino. E hoʻoikaika digestion a hōʻeleu i gastric emptying, gastroenterologists Paipai 'e lawe kūikawā' ana. Kekahi o ia haawiia ka lapaʻauʻia "Domidon". Na Ke Kumu no ka hoʻohana, manaʻo kōkua a me nāʻikepili o kēia k i hooku iho la ia ma lalo nei.

Palapala, haku mele 'ana, lāʻau'ōpala

Medicament "Domidon" aʻo ua waiho waho ma ka'ōpala i o ka pepa, hua mai la i ka papa palapala. Ka mea, hoʻohui pū i ka domperidone, a me nā mea hoʻohui e like me lactose monohydrate, povidone, ke kulina pia, microcrystalline kelulose, titanium'okikene lua, pregelatinized pia, makanekiuma stearate, paʻakai lauryl sulufahate, polyethylene glycol 4000, hydroxypropyl methylcellulose a sepifilm 752 Blanc.

Ma ke kuai ana o keia hale hele i ka contour keena.

pharmacology

He aha ka keia lapaau like "Domidon" (papa)? Na Ke Kumu no ka ho ohana i hākālia nō i ia mea he stimulant GI motility. Kona rula o ka hana ua wehewehe ia e ka hiki e aeie i ka D2-dopamine receptors. E like me ka hopena o keia hookoia maoli ka lōʻihi like 'ole o ka peristaltic neʻe i loko o 12 tiperstnoj naʻau liʻiliʻi, a gastric antral wahi. Kekahi hōʻeleu i ke emptying o ka olelo mai nā loko, a maoli he i ka leo o ka esophagus (ka lalo sphincter).

Kēia ka lapaʻauʻia ka mea i like me ia ma luna o gastric secretion. Kona Anati-emetic ia ma muli o ia i hoʻohui pū gastrokinetic kanawai, a me ka antagonism o dopamine receptors i loko o ka chemoreceptor kāhea kahi, a i aia mawaho i ke koko-lolo ke'ākeʻakeʻa mai. Eia hou, ua k eliminates hiccups a me nausea.

kinetic ano

He aha ka ano o ka kinetics o ka lāʻau "Domidon"? Na Ke Kumu no ka hoʻohana mau moʻolelo i koke, a maopopo ke kemu keia koʻi mai o ka naʻau liʻiliʻi. Ua Ua metabolized i loko o ke ake, a gastrointestinal'āpana paia, no ia mea, i ka bioavailability haʻahaʻa (puni 15%).

Hoemiia gastricʻakika wai a me ka ai ana me ka nui loa 'ūlōlohi mai ana, a emi ke omo o ka domperidone. Kona piko wai koko lehulehu loaʻa hoʻokahi hola ma hope, inu.

Palapala o ka lāʻau i ka wai koko nā polokina mea o ka hola 91-94%. He poorly komo iloko ma ka BBB, akā, ua hana pono ia i loko o ka makuwahine o ka waiū (ke ano mea e pili ana i 1/4 o ka heluna lehulehu i loko o ke koko).

Ke liluwelo hou 'ana o ka la hoomalolo ua lawe mai ma N-dealkylation a me ka hydroxylation.

Ka hapa-ola manawa o ka lāʻau mea 7-10 hola. I kaʻaʻa puʻuwai 'ole (loa), keia aka no ka hana.

Loko lāʻau, mai ka kino a me na feces a me ka mimi.

Nāʻikepili no ke komo

Ma kekahi mau hihia, nā mākua i hoʻokohu 'ia "Domidon" papa? I ka hana o keia k hōʻike i ka luaʻi, a nausea e like me kaʻeha i loko o ke keena abdomen, i ka manao o ke aupuni a me ka heartburn.

Like no na keiki, ka mea, Meu i keia hale wale no ka nausea a me ka luaʻi.

Contraindications

A hiki ole, e hoʻohana i ka lāʻau "Domidon" (kuhi no ka hoʻohana, a no ka mea ia mea - ia e nā mea a pau e hai aku i loko o keia 'atikala)? Contraindications o keia mea paahana, ua:

• gastrointestinal kahe ana ke koko;
• hypersensitivity;
• perforation o ka naʻau liʻiliʻi /'ōpū ;
• mechanical e intestinal iaʻi;
• hypophysisʻeho (prolactin-pee);
• ka hui pu ana me ka moʻolelo 'ano apau loa "Erythromycin", "ketoconazole"' ole 'ē aʻe nā mea kūpale o CYP 3A4, e like me Luna i hooloihi ai ia i ka wā mawaena Q-T.

Uluwehi O "Domidon": kauoha no ka hoʻohana

E wale nō e laweʻia i loko o noʻonoʻo huaale ma mua o ka meaʻai. I ka loaa ana ka lapaʻauʻia ma hope o kaʻai o ko lākou omo i kekahi ke kua'āina.

Children mai ka makahiki 12 a me nā mākua, keia ka lapaʻauʻia ua hoakaka ia 10-20 mg ekolu mau manawa o ka lā. ʻO kā mākou kela la i keia mahele lāʻau o ka lāʻau, he 80 mg.

Ka lōʻihi like 'ole o ka iniiaiie Inc - 4 pule. Inā pono, hou ana o ka lāʻau ua koi 'ia e kukakuka me kou kauka.

Me ka hooulu ana o kaʻaʻa puʻuwai ole e emi i ka multiplicity o ka lāʻau. Me ka pili ana i ka akepaa ole, ma keia hihia, ka mea, ua i hoakaka ia.

ʻaoʻao waiwai

I ka helehelena o adverse reactions lapaau "Domidon"? Na Ke Kumu no ka hoʻohana hai aku i na mea adverse 'ole mai ana:

• he mahuahua ma ka prolactin pae;
• anaphylaxis ;
• nervousness, manaʻo pīhoihoi;
• edema, hooloihiia mai ka wā mawaena Q-T, palpitations, dysrhythmia a me ka naau kōmi;
• maloo waha, extrapyramidal kāna hana, headache, ka makewai, Kanikani'āʻula, irritability, pōniuniu, drowsiness, lethargy, convulsions;
• gastrointestinal kāna hana;
• gynecomastia, galactorrhea, amenorrhea;
• ka ohane ame, dysuria;
• pinepine urination, ili lapuwale ia;
• stomatitis, conjunctivitis;
• asthenia,ʻeha ma nā wāwae;
• mahuahua ma ka AST, Alt a me ka naʻokoko.

kekahi koi

He aha e hai aku i ka hoomanawanui, ma mua oe hāʻawi i ka lāʻau "Domidon"? Na Ke Kumu no ka ho ohana i hākālia nō i hiki ole keia mea paahana e hui me ka antisecretory a me ka antacid lapaʻauʻia.

No ka iapaau ana o na keiki ma lalo o 12 makahiki o kona mau makahiki me ke kino kaumaha hoʻohana emi o 35 kg keia ka lapaʻauʻia e ole e.

Ma Inc me keia k e mea iki aku oukou alanui'ōnaehana a me ka hana me ka weliweli hana.

consumer hōʻike manaʻo

Ano, ia oe i ka hiʻona i ano o ka lāʻau "Domidon". , Ua hai aku ma luna Ke Kumu no ka hoʻohana, a no ka mea ka mea, o mākou.

Ka hapanui o nā mea kūʻai mai ka hoʻohana 'ana i kēia hale mai hai aku ia ia ka pono eliminates heartburn, hiccups a me nausea. Nō hoʻi, i ka lāʻau a hiki i ka poʻea pau o ka kokololio emptying o ka opu, hoemi i ka manao o ka ehaeha a me ka discomfort i ka palena iki.

Ka wale keakea o keia k o ka nui helu o kaʻaoʻao loa.