Hoʻokolohua-agonists: hōʻike, hana papa inoa o ka ai '

Kēlā me kēia lāʻau pili i kekahi mau pharmacological hui. Kēia 'o ia hoʻi i ai' kekahi i ka iaʻano papa hana o ka hana, nāʻikepili a me kaʻaoʻao 'ole. Kekahi o ka mea nui mea lāʻau lapaʻau pūʻulu - keia mea he Hoʻokolohua-adrenergic agonists. Mau ai 'e hoʻomano hoʻohana' ia ma ka lapaau ana o naehana hanu a me ka mea'ōnaehana mānowai koko pathologies.

He aha ka I-agonists?

Hoʻokolohua-agonists - he pūʻulu o ka 'inikua maalea, e hiki e lawelawe i loko o ka iapaau ana o ka maʻi likeʻole. Ma ke kino, ka mea, nakinaki i kekahi receptors aia i loko o ka'ōlohelohe Muscle o ka bronchi, uterus, naau a me ka vascular nā'aʻaʻa. Oia AaOIeIOUIeXAOAaIN kumu he stimulation o ka Hoʻokolohua keena. E like me ka hopena o ka ho'ā hope o nā physiological keʻano o ka hanaʻana. I ka paa ana o B-agonists i receptors stimulates ka? Iecaianoaaiiie o liluwelo konohiki, e like dopamine a me ka adrenaline. Kekahi inoa no kēia mau hui - Hoʻokolohua-agonists. Major 'ole o laila - hoʻonui o ka naau ana, mahuahua ke koko, a me ka hoʻoikaika' ana i bronchial conductivity.

Hoʻokolohua-agonists: i ka hana i loko o ke kino

Hoʻokolohua-agonists i maheleia i V1- a me B2-adrenergic agonists. Receptors no kēia mau 'ona i loko o ka na nā loko. I ka pū'āʻana i kā lākou Hoʻokolohua-agonists alakai i ka ho'ā hope o na mea he nui keʻano o ka hanaʻana i loko o ke kino. Aia nō i ka hopena kēia o B-agonists:

1. Mahuahua cardiac automaticity a me ka conductivity hou.
2. Hoomahuahua ae la lakou naau kōmi.
3. Hoʻonui o ka lipolysis. I ka hoʻohana 'ana, B1-agonists hou i loko o ke koko noa momoma nāʻakika a nō nā huahana o ka disintegration o triglycerides.
4. Hoʻonuiʻia ke koko. Kēia keia mea aie a hiki i ka stimulation o ka renin-angiotensin-aldosterone'ōnaehana (RAAS).

I ka helu loli ma ke kino,ʻo ia ka paa ana o agonists B1 receptors. Ka mea, i ke aupuni 'o ka naau Muscle, ipu koko, adipose'aʻaʻa a me ka juxtaglomerular nakeke o ka hakuʻala keena.

B2 receptors i aia i loko o ka bronchi, uterus, skeletal Muscle, Central ko mākou hopohopo nenoaiu. Eia hou, ka mea, i na ipu naau a me ke koko. Hoʻokolohua-2-agonists i ka hahai ole:

1. Hou ana o bronchial conductivity. Kēia keia mea aie a hiki i ka hoʻomaha no nāʻalā Muscle.
2. Hoʻonui o glycogenolysis i loko o nā nāʻiʻo. E like me ka hopena o skeletal Muscle wikiwiki a me ka nui hoemiia.
3. I ka hoʻomaha no ka myometrium.
4. Hoʻonui glycogenolysis i ake keena. Ua hiki aku i ka mahuahua koko kōpaʻa pae.
5. Hoomahuahua ae la lakou naau kōmi.

He aha ai 'i kekahi pūʻulu o B-agonists?

Kauka pinepine i hoakaka ia Hoʻokolohua-agonists. Ai 'o ia i kēia pharmacological pae, māheleʻia i loko o pōkole a me ka hoʻokēʻai-hana lapaʻauʻia. Eia hou kekahi, noho kaʻawale ai 'wale i kekahi e wae ia ma luna o kekahi mau nā loko. ai 'kekahi hana' ana ma luna o ka V1- a me v2-receptors. Na laau lapaau maikai-ike mai i ka pae ana o Hoʻokolohua-agonists i ai ' "Salbutamol", "fenoterol", "Dopamine". Nā agonists hoʻohana ma ka lapaau ana o pulmonary a me ka cardiac maʻi. Aʻo kekahi o lākou e ia i loko o kumu o ka mālama nui malama pa alima (lāʻau "Dobutamine"). Emi mai, he pono ole ai 'i loko o kēia hui e hoʻohana i gynecological hana.

Mea Maluna o ka Hoʻokolohua-agonists:ʻano likeʻole o nā lāʻau

Hoʻokolohua-agonists - keia pharmacological pae, i ka loaʻa o ka nui loa o ka lapaʻauʻia. No laila, ka mea, ua mahele ia i loko o kekahi mau pūʻulu. Mea Maluna B-agonists loaʻa:

1. Ole-e wae Hoʻokolohua-adrenergic agonists. Kēia pūʻulu nā ai ' "ortsiprenalina" a me ka "Isoprenaline".
2. E wae B1-agonists. Ka mea, i hoʻohana 'ia i loko o cardiology a me ka mālama nui malama nā papa. Me ka Poeikohoia o keia pae ana o ai 'i "Dobutamine" a me ka "Dopamine".
3. E wae Hoʻokolohua-2-agonists. Kēia pūʻulu nā lapaʻauʻia i hoʻohana no ka maʻi o ka naehana nenoaiu. I huli ai oe, ka mea e wae B2 agonist māheleʻia i loko o pōkole-e hana ai ', a me ka ai' me ka lōʻihi maoli nō ia. Ka mua pūʻulu nā lapaʻauʻia "fenoterol", "terbutaline" "Salbutamol" a me ka "hexoprenaline". Loa-e hana ai '- i ka lāʻau "Formoterol", "Salmeterol" a me "indacaterol."

Nāʻikepili I-agonists

Nāʻikepili no ka hoʻohana o B-agonists hilinaʻi nui ma luna o ke 'ano o ka lāʻau. Hoʻokolohua-agonists i ole-e wae 'ana ua manawa aneane i hoʻohana. Mua, ka mea i hoʻohana 'e hana i kekahi mauʻano o nā arrhythmias, worsening cardiac conduction, bronchial asthma. Ano kauka makemake e koi 'ia e wae B-agonists. Ko lakou pono o ia mea, i hiki poʻeʻuʻukuʻaoʻao ole. Eia hou, e wae ai 'hiki pono e hoʻohana, like wale pili kekahi nā loko.

Nāʻikepili no ka B1-agonists manao:

1. Huʻi naʻau ole.
2. Ke kŰia o kekahi etiology.
3. 'opi.
4. Decompensated naau mā.
5. Kākaʻikahi ka - ischemic naau maʻi koʻikoʻi loa.

B2-agonists lawelawe i loko o bronchial asthma, maʻi obstructive pulmonary maʻi. Ma ka hapanui o hoopii, e hoʻohana i kēia mau ai 'ma ke ano o aerosols. I kekahi manawa, ka lapaʻauʻia "fenoterol" ua hoʻohana 'ia i loko o gynecological mea e' ūlōlohi hana, a me ka pale miscarriage. Ma keia hihia, i ka lāʻau 'ua lawelawe intravenously.

Ma kekahi mau hihia, B-agonists i contraindicated?

Ua hoʻomanaʻoʻia ai ia i ka lāʻau hui A Hoʻokolohua-agonists i ka helu ana o contraindications a me kaʻaoʻao 'ole. He oi loaʻoiaʻiʻo i loko o ka ole-e wae agonists. ʻaoʻao 'ole o kēia mau ai' - .. Ua ka hooulu ana o ka hyperglycemia, lālā tremors, naau pāpana kāna hana, Central ko mākou hopohopo'ōnaehana excitation, etc. Hoʻokolohua-1 agonists i potent ai ', no laila, e hoʻohana wale i ka hihia o kaʻenaʻena nele. Ka mea, i contraindicated i loko o nā mea maʻi me ka mōʻaukala o ia pathology: ventricular arrhythmia, subaortic stenosis, pheochromocytoma. No hoi, ka mea hiki ole ke hoʻohana i cardiac tamponade.

B2-agonists i contraindicated i loko o ka kēia hihia.

1. Intolerance e Hoʻokolohua-agonists.
2. Hāpai keiki huikau e kahe ana ke koko, placental abruption, hooweliweli miscarriage.
3. Children ma lalo o 2 makahiki.
4. Hoʻoʻino keʻano o ka hanaʻana i loko o myocardium, cardiac arrhythmias.
5. Mimikō mellitus.
6. Aortic stenosis.
7. Hypertension.
8. Huʻi naʻau ole.
9. Thyrotoxicosis.

Medicament "Salbutamol": kauoha no ka hoʻohana

Uluwehi O "Salbutamol" pili i B2-agonists o pōkole hana. Ua Ua hoʻohana 'ia i loko o ka maʻi pale o bronchial iaʻi. Ka hapanui pinepine ia i loko o aerosols no 1-2 nā māhele (0.1-0.2 mg). Children he makemake ko e e ka inhalation i kekahi nebulizer. Aia Ua hoi he papa kino o ka lāʻau. Ka laʻau heluna no nā mākua mea 6-16 mg no ka lā.

"Salbutamol": lāʻau kumukuai

Ka lāʻau 'hoʻohana like monotherapy i mehana asthma. Inā ka hoʻomanawanui i lōpū ole loa ke kahua o ka maʻi, hooloihiia noi ai '(Hoʻokolohua-agonists loa-ua hanaʻiʻo akula). Ka mea, i na kumu o Inc o bronchial asthma. hoʻohana 'ana i ka lāʻau "Salbutamol" no ka poe ola, kokua o ka ho'āhewa wale' o breathlessness. Ke kumukuai o ka lāʻau mea mai ka 50 a hiki i 160 rubles ke kaumaha ma muli o ka Hookah, a me ka mahele lāʻau na i loko o ka hue.