Medicine 'Methotrexate'. i ke aʻo

Medicine "Methotrexate" kuhikuhi pili i ka Anati-metabolites waeʻano, pyrimidine analogs. Synonyms: "Zeksat", "Treksan", "Triksilem" a me na mea e ae.

O ia hoʻi, "Methotrexate" (papa) ua 'ae' ia e operative me he hookahi Agena paha i hapa o ka luna 'chemotherapy.

Ma nāʻikepili nā leukemia myeloblastic a me ka lymphoblastic, myelogenous leukemia maʻi pele i loko o ka ma hope ke kahua, lymphosarcoma. E like me ka hapa o ka noniakahi himiolecheniya lapaau "Methotrexate" alakai ia kekahi ovarian Ka maʻi 'aʻai, akemāmā, umauma.

At kiekie nā māhele (oiai loaa filinata kalipuna) lāʻau i hoakaka ia no ka osteogenic sarcoma, Ewing kaʻeho, choriocarcinoma uterine sarcoma o ka pahee'aʻaʻa.

Hoʻomanaʻo (ka pahu kui) ua hoʻohana 'ia e höʻike aku symptoms o ka psoriatic ili lesions.

O ia hoʻi, "MTX" i loko o ka Nine Inch 'ole (mea hoʻohana he mea' ike) kokoke i ka folicʻakika i keia i ke ku pono hopena. E like me ka antimetabolite hoa a me ka hoolako antifolievym hookoia, i ka lāʻau 'aʻole hoʻi ia ke kelepona hele mahele, e ulu ai o ka' Imi proliferating nā'aʻaʻa, iwi lolo like hoʻi. Ka medicament "MTX" ka poʻea pau i ka meheu o ka ulu ana o malignant neoplasms.

Ka lapaau Ua hoakaka ia maloko.

I ka luna 'ohe o ka lāʻau "Methotrexate" e manual ia kekahi kanaka makua i 0,03 nā huna palua i ka pule. No na keiki i ka mahele lāʻau no lā - 0,02 nā huna no huinahalike kenimika o ke kinoʻilikai wahi.

Duration o ka lapaʻau - i ia mau pule.

Mālama nui papa komo ai i ka hookohu o ka makua mahele lāʻau 0,02-0,025 nā huna kela la i keia. Duration o ka lapaʻau - i i elima mau lā.

I ka holo ana e lawe ka lapaʻauʻia "Methotrexate" e manual ia kekahi e lawe i ka mokuāhana i loko o kekahi a me nā pule.

Ka lapaʻauʻia contraindicated ma immunodeficient Hawaii, ake maʻi, thrombocytopenia, leukopenia, anaemia (me aplastic a apoplastic) hypersensitivity.

Not lawa ikepili e hoʻomaka pākōlea nā papa o ka lapaʻauʻia "Methotrexate" hapai a me ka lactating. Ma pili ana me keia ka lapaʻauʻia i loko o ka antenatal au a me ka manawa lactation ua ole ia.

Aia i ai ' "Methotrexate"ʻaoʻao ole. Ka lāʻau 'hiki i gagging, nausea, diarrhea, li nui ma ka moʻolelo o ka mucosa (stomatitis). Hooloihi ae i hoʻohana ana ai ' "MTX" ia lesion me kahe ana ke koko ma ka moʻolelo o ka mucosa o ulcerative ano, hoemiia platelet helu, lauoho poho, ua hoʻemi hemoglobin maʻiʻo i loko o ke koko. Ma kekahi mau hihia, haumāna maʻiʻaʻai hiki e malama, ao ao e i ʻawahia hepatitis (nō kāu ana ka wā kiekie nā māhele),ʻaʻa puʻuwai lesions.

I mea e pale aku i ke kūpono 'ana o undesirable hopena o ka pākōlea papa ka mea, ua lawe mai ma lalo o ka ikaika nā limahana o ke kauka.

I Ina o ka overdose ua i paa kekahi hoike ana. Diagnosing ke ano ua lawe mai ma kahi o ka lāʻau "Methotrexate" wai koko.

Cautions

Ua hoʻohana 'ia i ke koʻi i loko o ka pleural effusion, ascites, ulcers, ulcerative colitis, hakuʻala maʻi paha gout.

Mai lawe i ka lapaʻauʻia varicella (me ka nei Neʻe ma hope o hui 'ana me ka iho mailoko paha), herpes zoster a me nā huʻi maʻi o infectious kumu.

I ka hoomaka ana, a ma ka papa o ka iapaau ana mea pono e kūʻike ākea koko kiʻi, ake a me nā konāhua hope.

I ana i ka lāʻau ma ka psoriasis a rheumatoid arthritis, piha i ke koko ma ka helu pono i ma ka liʻiliʻi koke i ka mahina.

I loko o ka noiʻi ka mea i loaʻa mutagenic a me carcinogenic hopena o ka lapaʻauʻia "Methotrexate".