"Monosan": aʻo no ka hoʻohana 'ana, maoli counterparts

No ke aha la, a ma ka laʻau heluna hoakaka ia ka lāʻau "Monosan"? Na Ke Kumu no ka hoʻohana o vasodilator ai 'ua i ho'ākāka' ia i loko o au mamuli o ka pono o keia Haawina. Nō hoʻi ka mea, i kekahi mau medicament analogs, kona haku mele 'ana, pharmacological' ole, contraindications,ʻaoʻao 'ole, a laila, ma luna o. D.

Ke kinona,'ōpala, haku mele 'ana

He aha 'ona i kekahi hapa o ka lāʻau "Monosan"? Instruction hākālia nō i ka papa hehee ai o keia k mea isosorbide-5-mononitrate. Nō hoʻi, ke medicament maupaʻa i ka haku mele 'ana a me ka na adjuvants: talc granulated lactose, makanekiuma stearate, microcrystalline kelulose a me ka palaoa pia.

Ma ka palapala Manufacturers paka lāʻau "Monosan"? Na Ke Kumu no ka hoʻohana Hawaii i kekahi lāʻau hiki ke kuai lilo mai i loko o ka palapala o ka papa wale. Ka mea, i keʻokeʻo, a puni ma ka shape. Ma kekahiʻaoʻao o ka papa, aia mea he kamepiula.

Ka lāʻau 'ua pūʻolo helu ma blisters, a i aia i loko o ka noae o ka pepa pahu.

pharmacological hiʻona

Pehea ke ano o ka lāʻau "Monosan"? Na Ke Kumu no ka hoʻohana i ka 'ia ka lāʻau o keʻike ākea vasodilator, i hana kuhikuhi ma na ipu venous.

Ke medicament Ua hiki ke hoʻoulu i ka? Iecaianoaaiiie o vascular endothelium endothelial ko iala ololi e like me naikokene'okesaside. E like me ka hopena o ia 'ole ka ho'ā hope o wailana guanylate cyclase (intracellular'ūhū) e e iho maoli ka vasodilating uwao - cyclic guanosine monophosphate.

Ma hope o ka lawe i ka lāʻau i loko o aeee ho'ēmi i kā myocardial ka oxygen koi. O ke kumu ho i ka emi ma ka hana, a kia-preload.

No hoi, ua kakau hoʻomalu i ka haʻi ia koronarorasshiryayuschee ka lapaʻauʻia.

lāʻau waiwai

He aha nā lāʻau i ka waiwai "Monosan"? I ka hana o keia k ke emi i ke koko a hiki i ka atrium akau, a me ka nui loa ho'ēmi i kā ka puʻe i loko o ka pulmonary holo, a ho'ēmi i kā ka oolea o ka hopena maikaʻi symptoms o pulmonary edema.

It E e kaulana no hoi ia ma lalo o ka aoao o "Monosana" ma wahi me ka ilihune holo malaila mea he redistribution o coronary koko pele

Ma ke kāʻei kua o ka lāʻau i loko o kanaka me ka angina a me ka ischemic naau maʻi, me ka nui loa maoli ia'ku i kekahi physical haʻawina. Eia hou, ke kumuhana Agena mea hiki ia o ua hakumakuma ke HI kiko'î Thrombocyte hoʻololi kemikala a inhibit platelet aggregation.

pharmacokinetic waiwai

Where ka mea, ua paka, haawi a metabolized lāʻau "Monosan"? Na Ke Kumu ma ka noi Hawaii aho koke a maopopo ke kemu i ka hana o ka lāʻau waiwai, mai ka digestive'āpana. Ma hope o ka loaa ana o na papa io antianginal ia i malamaia ma hope o ka hola 30-45 minuke, a mālama 'ia no ka 10 hola.

E like me ka hoʻomalu, lāʻau "Monosan" i ke 'ano kiʻekiʻe uku o ka bioavailability (ka hola 99-100%). Keia mea aie a hiki i ka wa e kaawale aku o ka mua, e hele ia o ka lāʻau ma ka hepatic nenoaiu.

I ka hapalua o ke ola ana o ka lāʻau o 60 minuke. I ka lehulehu o ka lāʻau i loko o ke koko loli aʻe kānaka, ke kaumaha ma muli o ka kanaka.

Pūnao o ai 'ʻeleu waiwai i loko o ke akepaʻa. E like me ka hopena o metabolic keʻano o ka hanaʻana i hanaʻia o ka ekolu eiiiiiaiou: isosorbide glucuronide a me nā isosorbide-5-mononitrate.

hapa-ola manawa mea 4-5 hola. A pau keia 2.2% ua excreted Via kaʻaʻa puʻuwai'ōnaehana a 97,8% - like glucuronic metabolites.

nāʻikepili

Ma lalo o na hana hea ua häʻawi mai ai iä "Monosan"? I ka hana o keia ka lapaʻauʻia ka loa mana i loko o nā kēia hihia.

• pulmonary hypertension, pulmonary naau;
• maʻi ano o congestive naʻau ole;
• stenokardicheskie Kāohiʻana o hopu i loko o kanaka me coronary artery maʻi.

Contraindications

Ma lalo o ka kumu hiki ole e hoʻohana ' "Monosan"? Analogs a'ī akula 'o ia hoʻi iho ua papaia ia e ia ia:

• vascular'opi;
• i ka moku'āina o kŰia;
• arterial hypovolemia a me ka hypotension;
• cardiac tamponade ;
• haʻalele ventricular ole a me ka haahaa indices o diastolic ke koko;
• ʻawahia pulmonary edema;
• huʻi pae o myocardial infarction (me ka olelo hypotension);
• palapala-panina glaucoma;
• breastfeeding;
• maʻi i hoʻonāukiuki aku i ke ala o ka intracranial puʻe;
• kanaka hypersensitivity;
• i loko o nā keiki a me nā adolescents (mai a hiki i ka makahiki o ka hapa nui).

Ua E hoi e hoʻomaopopo i ka hōʻike 'ana no' o ia hoʻi ka mea, he pili contraindications. ʻO kēia ano pili iā ia:

• mitral stenosis ;
• constrictive pericarditis;
• wa e poohina ai;
• vascular kāna hana orthostatic hooponopono;
• ʻaʻa puʻuwai insufficiency'ōnaehana;
• hypertrophic cardiomyopathy;
• hyperthyroidism;
• hepatic ole ;
• aortic stenosis;
• loa anemia loko.

Uluwehi O "Monosan": kauoha no ka hoʻohana

Ohana Waikiki (International Nonproprietary Name) keia ka lapaʻauʻia kani e like "isosorbide mononitrate." Kēia lāʻau 'Ua lawelawe hōʻike waha wale. E like me na olelo, ka mea e e moni a pau, a holoi iho la me ka wai.

Papa e koho i kekahi kauka. I ka Ia manawa ka mea, ua koiia e Loiloi i ka oolea o ka nń ku mai o kona 'Isaaka.

"Monosanom" iapaau ana hoʻomaka me ka loaa o ia hoʻi, 10-20 mg 1-3 manawa i ka lā. Me 3-4 lā o ka Inc ka hoʻoponopono 'E e i dosing regimen. Inā pono, i ka nui o ka lāʻau, a mahuahua nui i 20-40 mg, a lawe papalua no ka lā.

symptoms o overdose

He aha e hiki ana i ka hoailona o ka overdose ka wā o ka hoomanawanui e loaa ana i ka hewa ka lapaʻauʻia "Monosan"? Na Ke Kumu no ka hoʻohana hōʻike i nā kēia symptoms:'opi, maʻule hou ihola nō, diarrhea maʻi pale, pōniuniu, hyperpnoea, redness o kaʻili, na kamalii uuku, dyspnea, tachycardia reflex ka molekumu o, headache, pyrexia, lethargy, nawaliwali, a mahuahua nui intracranial puʻe, pilikia makapō haunaele, ke kāʻili 'ana, lōlō, nausea, coma, sweating, ka luaʻi.

I ana i na olelo like i hoʻohana no ka manipulating gastric lavage, a i hoakaka ia enterosorbiruyuschee 'o ia hoʻi.

ʻaoʻao waiwai

Hana adverse lāʻau naoh "Monosan"? Na Ke Kumu no ka hoʻohana (analogs o medicament i hōʻike 'ia ma lalo nei) ua hoakaka ia e like me ka lāʻau i i ka helehelena o ka ai iiiaanoaa o kaʻaoʻao-loa. Mākou e hōʻike 'ia kekahi o ia mau mea:

• ka luaʻi;
• ke ahi ka waiʻona ma ma ke alelo;
• maloo waha;
• nausea;
• wela uwila;
• tachycardia;
• nitrate headaches;
• flushing o kaʻili ;
• pōniuniu;
• na hiohiona ka ho'ēmiʻana i loko o ke koko,;
• stenokardicheskie hoonuiia alapine (frequency) o ke kāʻili 'ana;
• Orthostatic hypotension ;
• hypersomnia;
• noʻonoʻo retardation a me Hawaii pane;
• oolea;
• blurred hihiʻo;
• e kukulu ana i ke ahonui,;
• kekahi 'ili rashes;
• exfoliative dermatitis.

Analogs o ka lāʻau a me kona kumukuai

A 'o ia hoʻi' oe hiki e puku i ka lapaʻauʻia «Monosan"? Analogues o keia ka lapaʻauʻia e loaʻa i loko o nā drugstore. Mawaena o ka loa ka hoʻokō mea hiki ke kālā līkaia "Monocinque lawelawe", "Izoket", "Kardiket", "Efoksa", "Pektrol".

Like no ke kumukuai o ka lāʻau, ia mea,ʻaʻole loa kiʻekiʻe. E hoʻomaopopo mai lāʻau i loko o Lūkini kulanakauhale hiki 100s (30 papa) wale no.

e hoike

mākou e noonoo pono i ka lāʻau i ka hailona o maikaʻi manaʻo. E hoomanawanui i hoʻopaʻapaʻa ana i ka mea hoi me he loa ka hoʻokō Agena no pulmonary hypertension a me ka maʻi naʻau ole shape. Naʻe, ka mea e e kaulana ia no ka loaa ana kiʻekiʻe pākōlea hopena e like me ka lāʻau e e hui me ka 'ē aʻe ai'. E hana i kēia, eʻoiaʻiʻo, e kukakuka lakou i ka hele kauka.

I makemake kekahi makemake e hoailona oukou ia ia he nui loa nā mea maʻi e makemake kumukuai i hoʻouna 'ia ma ka lāʻau. I haiia ae maluna,, 30 papa oe e i e uku wale 100 Lūkini rubles.

Mākou hiki ole ke olelo ia e pili ana i ka lāʻau a me ka pinepine haʻalele io manaʻo. Ma ka hapanui o na hihia, ka mea e pili ai me ka helehelena o ka ai iiiaanoaa o kaʻaoʻao-loa. Ma ke ala, ka wā e hoʻomaka ai mai ka 'ai, inu E e haalele a UAIAaIN e nui kona i hoopaa ia mea. He aha kēia nui, oe e e hiki ke hai aku ia wale nō ka hoao ana i ka hoʻomalu.