Mycobacterium tuberculosis: anoʻikepili microorganisms

Mycobacterium tuberculosis (Koch ka bacillus) - gram-maikaʻi kookoo-hoʻokino koʻohune a hiki hana ka pae-e like 'ole. Ka mea, eʻakika-hoʻopale a nō iloko o ka hailonaʻana no lipid a me ka mahuahua i loko o kona pa, a hoʻoholo lākou ia'ku i ka dezveschestvam, Map a me ka maloʻoʻana. Mau microorganisms mea ino i nā pōpō me ka aniline make , a kuhikuhi kiʻekiʻe pathogenicity a me ka hydrophobicity.

It E e kaulana ia mau kūikawā morphological ano o koʻohune i coccoid 'ole a me ka L-ano, eia nae ka hapanui o ia - mea lahilahi, a pololei, a iki uma mau laau la. Eia kekahi, Mycobacterium tuberculosis hoʻohui pū i loko o cytoplasm Leo mānoanoa (kekahi granulesʻakika labile).

Inā mākou e kamailio e pili ana i ka moʻomeheu waiwai o kēia mau koʻohune, ka mea i facultative anaerobes a me aerobes. Ko lakou ano hiʻona - ulu loa lohi, a me ka nele i kumuʻiʻo a me ka glycerin no ka holomua? Aneii. I ka wai a me Media, i kēia mau microorganisms hana i kaʻilikai ho film. Ma anuanu nutrient Medium Mycobacterium tuberculosis ma nā'ōleloʻano o ka maloo wrinkled patina creamy kala like 'ole,ʻikeaʻana o ko lākou mau panalāʻau e hoohalike ai cauliflower.

pathogenetic hiʻona

Ke kumu nui ololi o ka pathogenicity - "kaula ololi". Ua glycolipids, a hoomalu nae lakou i ka Koch bacillus mai phagocytosis, a hooholo i kaʻawahia'aʻaʻa hanaʻino i ke kanaka hoʻomanawanui. Ua E hoi e hoʻomaopopo i ka M. tuberculosis luna 'i wehewehe aku e kekahi lākou o nā antigens, no laila lākou' ike ua aneane loa hoʻohana 'ia no ka antigenic waiwai.

Ina paha tuberculosis ho'īli? Ke epidemiology o kēia maʻi, he ekolu 'ole o ka EYI. He airborne, holoholona iho mailoko o Via ka waiu (alimentary) a me ka airborne lepo. Ua pono e mai la oia i kekahi kanaka ma ke ola o kona kulana pinepine ma ka hui 'ana me na konohiki o ka tuberculosis, akā, i ka maʻi, aole ia i hoʻomōhala i ka mea ia manawa, ke kaumaha ma muli o ka ia'ku o ka meaola.

Koch ka bacillus pinepine komo iloko ma ka naehana'āpana, a i pio ma na macrophages. Hou ma ka wahi o ka ingress o koʻohune hana bronhopnevmonichesky kālele ana, e like me ka li nui o nā 'āina' lymph aka wahi. Ke iniiaiie kumu o ka maʻiʻaʻai ke kāhea pneumonia a me generalization o tuberculosis. Ma ka ia'ku kiʻekiʻe o ka meaola Mycobacterium oki i ka paʻi. I ka Ia manawa, e noho lōʻihi ma ke kino, a hiki e ho'ā 'ia paha ma ka hailonaʻana o ka makahiki.

Au pono aku nei au i ke kakahiaka nui ka loaʻaʻana o ka tuberculosis maoli ka manawa o ke ano ka hopena o ka maʻi. I kēia lā e increasingly hoʻohana i ka hope PalekanaEND_LINK ki ina hana like, mawaena o a ke alakai wahi ua ku e ke polymerase kaula naoh.

A lohe o PCR 'aʻole e huai ae TB bacillus Koch DNA a hiki i ka hihia o ka palena iki dala e hoʻokūpaʻa i ke kūpono' ana o ka maʻi hiki ole ia i kekahi'ē aʻe ala. Eia hou kekahi, PCR mea oluolu, e huai ae mycobacteria ia'ku i kanaka ai '. He lawa ke hoopaa ia i na nā'ōewe i nā kuleana no ka mea koʻohune ia'ku i ka rifampicin, isoniazid a okoa lāʻau waiwai, e lawe emi o 48 hola.