Alpha-fetoprotein ma maʻamau a me ka pathological ana

Alpha-fetoprotein mea he mea o ke kumuʻiʻo me Kinohi a ua hua mai i loko o ka yolk sac o ka embryo ma hope o ka hānau - i loko o ka digestive'āpana, a ma ke akepaʻa keena. Maʻamau, ka mea, ua loaʻa ma loko o ke kino a hiki i 15 ng / ml.

Alpha-fetoprotein ua nānā 'i hāpai keiki, e diagnose mā o ka fetus. Ua loaa noi ka wehewehena o ke anakahi, a ma ka oncology. Alpha-fetoprotein mea oncomarker testicular Ka maʻi 'aʻai, a ake. Ma kahi o 70% o nā kānaka me ka testicular hikoko ua kiʻekiʻe, ka oi aku ma ke kaʻina hana o ka metastasis.

Initially, ia mea he kumuʻiʻo waiwai synthesized i loko o ka ovaries, ke kino luteum. Ma ka hebedoma lima, i ka fetus hoʻomaka e paka kona iho. Alpha-fetoprotein i malama i ka fetus mai o ka makuahine i ka'ōnaehana paleʻea'ōnaehana, no ka a ia mea he haole Agena.

Kona lehulehu ua hoomahuahua ia i like me ka embryo koko a me ka maternal koko. Ka e pono ai ke kumukuai o keia aiao no kaʻike, - ma 12-16 pule. Ma 32-34 pule o ka hāpai keiki kīnā ka i kā mākou kiʻekiʻe o Alpha-fetoprotein. ola kanaka kūmau ua loaʻa i loko o ka makahiki mua o ke ola.

Research ki ina hana like me ka nui loa pili ka wehewehena o ke anakahi. Nui oluolu inoa abnormalities o Alpha-fetoprotein i ka multiplicity o ka Media (makuahine). Ke Median o ka waena helu i loko o ka kauoha aiee o ke kumuʻiʻo lehulehu i loko o maʻamau hāpai keiki i loko o keia makahiki. Penei, kekahi ke hoohalike i ka Alpha-fetoprotein hāpai keiki ma kekahi kahua o ka hoʻonaʻauao, a kālailai i kekahi i loko o kekahi keʻena hoʻokolohua. Pae o keia 'inideka mai ka 0.5 hiki i 2,5 makuahine e maʻamau.

Mahuahua ka AFP hiki e ka PAaIEN o:

• Hikoko o ka bronchi.
• Ake metastases.
• Cancer o ka opu, pancreas, akemāmā, akepaa, AeXIeAaOIePEAaI, umauma.
• Embryonic testicular a ovarian hikoko.

Manawa a marginally māhuahua Alpha-fetoprotein i loko o ka hahai pathologies:

• Ake cirrhosis,
• Maʻi ake ole,
• Alcoholism i ke alo o ke akepaa eha,
• Maʻi a huʻi mea hoʻomaʻi hepatitis.

Kēia huahelu mahuahua i hāpai keikiʻia i loko o ka kēia hihia.

• Mau hāpai keiki.
• ʻaʻa puʻuwai mai i loko o ka fetus.
• Umbilical hernia i loko o ka fetus.
• Fetal ake necrosis.
• Malformations o ka neural Tube (rahishizis, anencephaly).
• Mauae o ka mua paia o ka abdomen o ka fetus.
• Nā malformations.

Eia naʻe, hoemiia Alpha-fetoprotein ma ka hāpai keiki e hōʻike i nā kēia:

• Wahahee hāpai keiki.
• Developmental ke kali ole.
• Fetal make.
• Molar hāpai keiki.
• Noho'na makaainana i ulu abortion.
• Trisomy o chromosome 18 a me 21.

Ka hoemi lehulehu o Alpha-fetoprotein e hōʻike i ka pololei ole hoʻoholo o ka lōʻihi like 'ole o ka hāpai keiki,ʻo ia hoʻi, i ka hapai ana hanaia hope.

I gynecology ma ka keia ke kahua o ka iniiaiieʻeleu anakahi peni mäka o fetal chromosomal kāna hana, a pathologies o ka hāpai keiki. Deviations mai ka maʻamau fetal kūpono 'hoololi i ka maʻamau lehulehu o ke kumuʻiʻo' ona i loko o ke koko o ka makuahine, o ka. O ka holo ana, aole e e ole wale no ka ho'ākāka 'ana o kēia anakahi, e like me ka mea i informative. Pono Pono e hoʻomaka ultrasound haʻawina, e ka mea e hiki ke hōʻoia i ka pono ka wehewehena o ka makahiki, mau hāpai keiki, a no laila, ma luna o. No hoi, ka mea i Kuleana i ka hōʻike a me ka placental hormones (chorionic gonadotropin a me ka estriol noa), hele 'ana o ka pololei auhau o fetoplacental kahua. Ko lakou hui pu ana me ke Alpha-fetoprotein ua ho'ākāka 'ia i loko o ka Triple hoao ana i leie aku e hooholo i ka pilikia o keʻano o malformations i loko o ka fetus.