Anticoagulants - ai 'e aloha ia ke koko clotting

Ma lalo o maʻamau rula, ke koko o ka wai a hoʻolako i ka neʻeʻana o kona circulatory kahua. Ma infectious a parasitic maʻi, e like me intoxications hoʻololi i kona physico-Nine Inch ka waiwai, a he kūlana e loli ai i ka metabolic keʻano o ka hanaʻana, a me ka functioning o na nā loko. Penei liluwelo manaʻo nui i clotting kōmi. Ua hiki e hōʻeleu i a hoolohi. I ka lapaau, e hoʻohana i ka hailona o pharmacological Luna a me ke kōkua o ka i oe e hoʻomaʻa i ka mämä holo o ke koko clotting. Anticoagulants - ai 'e' ūlōlohi mai ana i ke kaʻina hana o ka coagulation o ke koko, e like me ka mea e hōʻeleu i keia aiiay pane, kapaʻia coagulants.

Keʻano papa hana o ka coagulation a me ka thrombus ho okumu - he luna 'biochemical kaʻina mea i malama i ke kino, mai ke koko me keia poho ma vascular ano hoopono kue. Kēia kaʻina ua lawe mai ma ka lilo o ka prothrombin, i ua synthesized i loko o ke ake, a me nā platelets, a hoopili i ka collagen olona, o na kihi o ka moku poino. Ma ka hydrolysis kaʻina anao? Aou platelet-waiwai i huiʻia (adenozintrifosfatnaya a adenozindifosfatnayaʻakika), thromboplastin a me vasoconstrictors - norepinephrine, epinephrine, serotonin. Ka mea, pilikia ka moku lumen. Thromboplastin ma lalo o ka aoao o ke kalipuna a me ka wai koko nā polokina e pili ana me ka prothrombin a me ka thrombin ano, i mea he kumuʻiʻo (fibrinogen) ua hoohuliia i ka insoluble fibrin, hoailona iho la i ka vascular lumen.

Koko clotting 'aʻole hoʻi mai pili me ka hoemi kalipuna pae i loko o ke koko, he emi ma ka platelet helu, prothrombin hoʻololi kemikala kāna hana o ka fibrinogen, thrombokinase lawa haʻawina a me ka wikamina K. Ka coagulants hoʻohana ma ka lapaau, thrombin, fibrinogen, kalipuna koloriside, menadione, aminocaproicʻakika, nō hoomakaukau (paʻapū lau, wai kekahi pahūpahū).

Anticoagulants - ai 'i inhibit ka liluwelo hana o ka'ōnaehana, i hoakaka koko coagulation, a ua ālai' i ke kahua o ka clots i loko o na moku ke koko. Ka mea, inhibit a pau a me kekahi o nā kūlana o ke koko clotting. Ua ua ike ia ke koko wai moku'āina ua mālama 'ia e kekahi' nā'ūhū a me ka antitrobminom. I mea e pale aku i ke kahua o ke koko clots, anticoagulants hoʻohana pololei hana. Ka mea, he aha ka mea i ke koko clotting kumumea lohi i ke kaʻina hana i loko o ke kino a me Tube. Paʻakai citrate (paʻakai citrate) a me EDTA (ethylenediaminetetraacetateʻakika) nakinaki i ka ionized kalipuna o ke koko, a hoohuli ia i loko o kalipuna citrate kekahi? Eiiieaena me EDTA. I e pili ana me ka wehe 'ana o ke kalipuna Ion, mai ke koko clotting'ōnaehana ua hana thrombin a me ka fibrin. Heparin inactivates thrombogenic aʻe, a inhibits i ka huli ana o ka prothrombin i ka thrombin. Anticoagulants - kauoha hana o ka ai 'i hoakaka ia no ka transfusion a me ka hematology keʻena hoʻokolohua haʻawina no ka Kāohiʻana o ke koko clotting, a no ka hana o ka maʻi i pū' oe me ka hōʻeleu i ke koko clotting. Mau ai 'i hoʻohana no ka Kāohiʻana a me ka hana ana o thromboembolic complications.

Anticoagulants oʻauhau'ēʻaʻe hana - bishydroxycoumarin, coumarin, sinkumar - aeie i ka hoʻololi kemikala o nā'ūhū i ka pae'āina i loko o ke koko clotting. Ka mea, inhibit thrombin ho okumu ma ke akepaʻa. Kēia kaʻina hana e hoʻomōhala ana i loko o ka meaola i loko o 12-72 hola, a ua hoike mai ia ma ka au o ka mai mau a hiki i na la he umi. He He lōʻihi-hana lapaʻauʻia. Anticoagulants - ai 'ʻauhau'ēʻaʻe hoakaka no ka Kāohiʻana a me ka lapaʻau o thrombosis, embolism, thrombophlebitis.