Coagulation - He aha ka mea? Ho omńkalakala i ke koko coagulation: nā hoailona a me ka lākiō o

"Coagulation - He aha ka mea?" - noi ma ka haohao, e hoomanawanui i ka poe i hoounaia mai e lawe ia ka Ka Ikepili. I ka mea, eʻalo ano o kanaka me ka like ao infrequently, IeAUPIIe, IAa IO i ka makaukau no ka kohoʻoki kino. Höʻailona oʻeleuʻia a me nā mea a pau hapai wahine. Ka Ikepili o ka coagulation kaʻina hana o ka e hali ana i ke keiki o na trimester.

Ma lalo e hoʻohoka hua'ōlelo study moe kahe ana ke koko. E hoʻopaʻa i ka aʻo kiko'î ke oko ma ke keʻena hoʻokolohua. Ka Ikepili mea hōʻike, a ua kauohaʻia. Ma ka hihia mua ka mea, ua manao wale nō i loko o i 'ana Loulou clotting kaʻina' aʻe 'ana. Coagulation ua kauohaʻia - 'ano o ka noiʻi, a, ma ka hou e qualitative a laupaʻi haʻawina a me nā mā. Ua hiki ke hoʻohana i ka hōʻike platelet kāna hana, na thrombosis, deficiency o kekahi clotting kumumea a me ka e like. D.

Ka 'ia paha o nā kiʻina hana a hoʻohana' e loaa i ka? Acoeueoao hilinaʻi nui ma luna o ka lapaʻau kiʻi, ke 'ano o ka pathology Ka Ikepili. It E e hoʻomaopopo i ka transcript o ke koko coagulation - keia mea he nui ka hakaka ana, aole no ka mea i loko o wale, akā, i kekahi manawa no hoi i ke kauka. Nō kāu, i mea e hana i ka pololeiʻike, ka mea lawe i ka luawai-i waeia mau ho'āʻo ma.

I ke kaʻina hana o ka koko coagulation

E pehea ka clotting'ōnaehana mana mākou noʻonoʻo. Ma kaʻanuʻu mua o ka Nine Inch ai ÿole mechanical poino i ka moku paia ua anao? Aou thromboplastin - kūikawā waiwai triggering coagulation naoh. A laila, ho'ā hope o clotting aʻe i wahi - ho'ākāka nā polokina mea maʻamau mau makana i loko o ke koko, a i ka paena o ka eha ana o ka moku paia thrombus ho okumu.

Eia, thrombin (i ka aoao maoli ke keʻena o ka coagulation'ōnaehana mai ana prothrombin) haʻalele no ka AEeOEXAaI kumuʻiʻo fibrinogen, pio ia i loko o kaʻeleu fibrin clot 'ano apau loa ke kumu. Na oihana mua o ke koko, e like me platelets, "pilikia" i loko o ka mea ulana pukapuka, o ke fibrin. E like me ka hopena, koko platelets clot oki, a ua hoʻoikaika i ka hana i ka oʻo thrombus panina hanaʻino i ka vascular pa. Akä naÿe, i ke koko coagulation'ōnaehana i loko o ke kino i mana protivosvertyvaniya nenoaiu. Together e ae oe e malama i ke koko i loko o ka maʻamau moku'āina.

clotting haʻawina ma ka hapai

E like me ua oleloia, kēlā trimester, a ma kekahi hihia, a oi pinepine, hapai wahine e coagulation. He aha ka mea a ke kumu o ka mea pono, expectant makuwahine ike firsthand. Ka mea ka ia i gestation bebe hope o ka coagulation'ōnaehana like me ka a pau ua hou. He He maoli kaʻina hana pili i nā mea i Konakele. Uteroplacental koko kaiapili lapaau. Ke expectant makuahine no laila, e hoomakaukau ana no ka mea e hiki kahe o ke koko i ka nahunahu hanau.

E kuhikuhi i nā hiʻona o ke koko clotting a me kekahi complications o ka hāpai keiki hua coagulation. Kekahi, Ka Ikepili ma unscheduled manawa kahuna lapaau e pono ke noi aku ina he mau deviations, mai ka maʻamau hemostatic kiko'î (eiiiiiaiou o ke koko a me ke koko moku, i leie aku AaOIeIOUIeXAOAaIN malama i ka pono o ka vascular paia, a kahe ana ke koko ma ka hihia o ka poho ana). Koko no nā haʻawina ia i loko o ke kakahiaka ma luna o ka nele'ōpū mai kekahi aa koko.

Ho omńkalakala i ke koko coagulation

Ke ao hopena o ke Ka Ikepili E ke kapu i ka hoʻomalu. E loaa no kūikawā ike, kanaka,ʻaʻole e hiki iā decipher i ka coagulation kiko'î a Loiloi i kā lākou degere o ka haiahū kūmau, mai ka mea maʻamau i nā loina e. E mākou ho'āʻo e maopopo i nā intricacies o ke kaʻina hana, a wehewehe i ka walaʻauʻana kiko'î o ka mahele.

1. Fibrinogen

Kēia kumuʻiʻo ua synthesized ma ke akepaʻa, haliu ae la ia ma lalo o ka aoao o kekahi koko kumumea i ka fibrin. Keia huahelu Pono e komo i ke coagulation o ke koko. Normal fibrinogen - 2-4 g. / Ho'āo ai. Inā ka mea, ua mahuahua, ke 'O ia hoʻi clotting māhuahua, a me he mea he pilikia o ke koko clots. Nō kāu, keia kahua ia lŘlŘ mua hanau, pneumonia, ma hope oʻoki kino, me ka maʻiʻaʻai a me ka li nui o ka huʻi ano (tuberculosis, maʻi palū), myocardial infarction a me ka hahau ana (i ka lā mua), a me'ā, hypothyroidism, ku una contraceptives a me estrogens. Hoemiia fibrinogen paha e no i kaʻawahia, cirrhosis paha hepatitis i loko o ka nui palapala, he deficiency o ka wikamina B12 a C loaa androgens anabolic steroid, iʻa aila, anticoagulants.

2. ho'ā 'hapa thromboplastin manawa (APTT)

Coagulation huli aku i ka manawa a ma ia, hope e pili ana i ka wai koko kalipuna koloriside a me nā waiwai i hanaʻia i ke koko clot. Inā ma ka liʻiliʻi loa kekahi coagulation ololi o lalo o ka kūmau ma 30-40 pakeneka, aPTTʻilikai loli. Ka mńmń holo 'awelika o 30-40 kekona. I ka manawa e hoonui me ka wikamina K deficiency, ake maʻi. Ke kumu no ka hoʻolōʻihiʻia ka aPTT, a like me kaʻilihune, ae hoolohi coagulation hiki e hemophilia.

3. Lupus anticoagulant

Kēia aiao mau kekahi mau ka coagulation. He aha ka keia aka? Owai la ka mea e hai aku. Kēia lāʻau lapaʻau kino IgC a me IgM, entailing ka hoomahuahua i loko o ka aPTT. Maʻamau, hapai wahine, ka mea e ole e lawe. Nā mea'aʻaʻa ikeia ma ka hihia o autoimmune maʻi, gestosis. Hāpai keiki me keia pathology pinepine hopena o ka noho'na makaainana i ulu abortion, fetal make paha infarction ana o ke keiki.

4. Prothrombin

He He luna 'kumuʻiʻo ia mea he precursor o thrombin (ke kumuʻiʻo e stimulates i ke kahua o ke koko clots). 'O kēia kekahi o nāʻano nui nā hoailona o ka coagulation. Prothrombin, a me ke komo o ka wikamina K ua synthesized ma ke akepaʻa. Ma hope o ke kālailai keia nui, he kahuna lapaau i kuhikuhi pathology gastrointestinal'āpana a me ka akepaʻa.

5. Ka prothrombin manawa

Ka manawa manawa i ka wai koko ma ka pepa ia kalipuna koloriside, thromboplastin a me ka fibrin clot hana. Kēia aka ua olelo ia i loko o kekona, a mea maʻamau like ia 11-15.

6. Prothrombin Index (ili n)

Coagulation pinepine komo ai like keia koho kahi o ka mea mua kekahi. Kēia lākiō o ka clotting manawa o ka maʻamau kanaka wai koko a me ka wai koko o ka hoomanawanui, kaheaia like me ka pakeneka. Ma maʻamau prothrombin hiʻohiʻona E ĸokoĸa ana nä pane ma waena o 93-107 pakeneka. Makaʻu o keia aiao e synthesized ma ke akepaʻa keena, ake maʻi lākou helu ua hoemi, no laila, IPT hiki i kekahi papahelu malama like aiao no ka hoomaopopo ana i ka ooieoeiiaeuiiai moku'āina o ke kino.

Inā ili n māhuahua, no laila, clotting ua mahuahua, a me he mea he pilikia o ka thrombosis. Ulu hiki i ka wa e lawe ku una contraceptives, a ma ka mahina hope o ka e hali ana i ke keiki ana. Ka ho'ēmiʻana o ka prothrombin inideka Hōʻike he mea hōʻemi o ke koko coagulation waiwai. I ka ho okumu ana o prothrombin luna 'aʻe e kaukaʻi ma ka wikamina K, nae kona keakea, malabsorption i loko o ka naʻau liʻiliʻi (dysbacteriosis, enterocolitis) a i entail ka ho'ēmiʻana IPT. No hoi, keia e 'ai pono i ka lawe ana kiʻekiʻe nā māhele o ka aspirin, diuretics.

7. Thrombin manawa

'O kēia ka manawa manawa a ka fibrinogen ia iho i loko o fibrin. Kona normative cia - 15-18 kekona. Ke mahuahua i loko o keia 'inideka ua malamaia ma ka congenital nele i ka fibrinogen a me ka loa ake ka pōʻino. Ka ho'ēmiʻana o ka aiao, oa ka ka ho'ēmiʻana o ka thrombin manawa, Hōʻike i ke alo o ka paraprotein (immunoglobulin kumuʻiʻo) a me ka oi o ka fibrinogen. Nō kāu, ke anakahi cia hooponopono i lapaʻau fibrinolytics a heparin.

8. Antithrombin III

He he inhibitor o thrombin, he kumuʻiʻo anticoagulation kahua. He ua he e kaumaha ana ia ma luna o ka coagulation kaʻina. Level anakahi hoʻoholo ma ka paa ana o thrombin i loko o ka hoao ana hāpana (inhibition). Ka waiwai o ka antithrombin III - 71-115 pakeneka. Ka ho'ēmiʻana okoʻa no ka manawa i 50 pakeneka o ka maʻamau entails i ka pilikia o ka thrombosis.

Ka wehewehena o keia anakahi mea nui oi loa aku hoi no ka hapai wahine e lawe anticoagulants. e hoʻohana 'ia kēia mau ai' i loko o ke keiki-hanau ana, i ka wa a ke koko clotting ua mahuahua, a me he mea he pilikia o ka ho okumu ana o placental insufficiency, hāpai keiki hoopau wale.

9. D-dimer

He mea nui i anakahi no kaʻike, o ka thrombosis, i ka loaʻa o coagulation. Kēia aiao hōʻike? He hōʻike na keʻano o ka hanaʻana o ka thrombosis a me ka fibrinolysis. Maʻamau, D-dimer mea emi o 248 ng / ml. Ka 'ilikai anakahi e hoʻomaka ana e ulu ana ma na kahua o ka hoʻonaʻauao kakahiaka o ka hāpai keiki. E haʻalele i ka aiao cia e oi aku i ka loiloi mua 'ekolu i eha manawa. Ua Ua noʻonoʻo pono i ke kūmau. A oi aku ana i ka wahine me ka huikau papa o ka hāpai keiki (preeclampsia), e like me ka pono me ka poe e ae mai hakuʻala maʻi, mimikō.

10. Platelets

Ua komo i loko o ka hoʻolako 'hemostasis platelets. Ka mea i hanaʻia i loko o ka iwi lolo. Normative cia - 150-400 tausani / ml. Ma kekahi mau hihia, ma ke ola o na wahine e 'ike i ka emi ana ma ka platelet helu i 130 tausani. / L. Nui emi i loko o ke kokoʻikepili oihana mua i kapaia "thrombocytopenia" a ia lŘlŘ like me ka hopena o ka hoemi i ke kahua o platelets, mahuahua lākou hokii, a me ka make. Me ka lawa kino hoemiia platelet ho okumu. Ma DIC, a e e kūkā mai ma lalo nei, ka mea, ua ho'ākāka 'ia ma hoʻokino koko keena, piʻi pū.

11. DIC

AaOIeIOUIeXAOAaIN o platelets, coagulation kumumea a me fibrinolysis kaʻina hoʻolako i ke kaulike ma waena o coagulation a me ka anticoagulation nenoai. Inā e undergo kekahi o kēia mau loulou kāna hana ma ka hāpai keiki hiki i kekahi complications nui. Ka noho pilikia loa o ia ua hoʻolaha intravascular coagulation. Ua hoʻomōhala ana i like me ka hopena o ka ho'ā hope o fibrinolytic'ōnaehana a me ka coagulation nenoaia. I ka hapai nā wāhine, nā kumu o DIC i e amniotic loli embolism, premature poe o ke keiki, endometritis.

12. ka antiphospholipid maʻi pale (APS)

He He luna 'o symptoms mea i emi iho thrombosis (venous a me ka arterial). Women me APS i ke kiʻekiʻe kamepiula o miscarriage a me ka hanana o ka noho'na makaainana i ulu abortion, no ka mea, ma keia hihia na mea ulu i loko o ka helu ana o na moku o ke keiki ua pilikia a me ka ulu fetoplacental insufficiency. E diagnose Anati-phospholipid maʻi pale, mahuahua thrombogenesis ma ka hou, i huai ae nā mea'aʻaʻa i ka pā iwi membranes (phospholipids).

ma ka hopena

coagulation noonoo nā hoailona i ole exhaustive. I kaulana ma luna, i ke koho ana o kiko'î a no ka hoʻopaʻa 'ana i hilinaʻi nui i likeʻole aʻe. i ka ia la ae, ma hope o ka haawi ana i ke koko, e e loaʻa hopena o ke Ka Ikepili.