Medicine 'MabThera'. Na Ke Kumu no ka hoʻohana

Ka waeʻano o anticancer ai 'nā lāʻau "MabThera". Description medicament Hōʻike kona hiki ana i ua hōʻike hewa hoopaa i ka transmembrane antigen makana i loko o 95% o ka non-Hodgkin ka lymphomas, B-aeea palapala. ʻeleu ke keʻena - rituximab.

Medicine "MabThera". Na Ke Kumu: hoike

Ka lapaʻauʻia i hoakaka ia no ka B-aeea ole-Hodgkin ka lymphoma:

- himioustoychivoy a recurrent, CD20-maikaʻi me ka haʻahaʻa-papa paha follicular;

- follicular ekolu paha hā o ke kahua ma ka hui pu ana, me ka chemotherapy i loko o nā mea maʻi i mua olohelohe ia lakou i ka iapaau ana;

- ma hope o ka follicular pane e hoʻokomo Inc me he kākoʻo mea;

- CD20-maikaʻi B-nui-ma ka hui pu ana, me ka kua chemotherapy noaia.

O ia hoʻi, "MabThera" e manual paipai no ka maʻi lymphocytic leukemia :

- ma ka hui pu ana, me ka chemotherapy i loko o nā mea maʻi i i ole ua malalo i ka maʻamau lapaʻau;

- recurrent a himioustoychivom ma ka hui pu ana, me ka chemotherapy.

Medicament hōʻike nā mākua me kaʻeleu ano o rheumatoid arthritis ma ka hui pu ana me ka medicament "MTX" lawa ponoʻole ka wā noi hypersensitive pane a pākōlea regimens.

Contraindications

ua i paipai 'o ia hoʻi "MabThera" aʻo ina oe e hypersensitive.

pono e kū'ē'ē ana mālama nui ia ka lawelawe ana ai 'ana i nā mea maʻi me ka arrhythmia, angina, congestive naau e hemahema, kiʻekiʻe a haahaa ke koko, thrombocytopenia, neutropenia, COPD (aie i ka pahiki o ka hanana o ke bronchospasm).

ʻaoʻao waiwai

I ana i ka lāʻau "MabThera" E pono anei i nausea, abdominalʻeha, ka luaʻi. Ka hopena maikaʻi hoike ana i nā orthostatic hypotension, arrhythmia, tachycardia, bradycardia, hoʻopilikia o kaʻaʻa puʻuwai hana,ʻike ākea edema,ʻeha i loko o ka pahu, a lumbosacral spine wahi. Ka lāʻau "MabThera" hiki iʻike ākea neuropathy, neuritis, drowsiness a Kanikani'āʻula, manaʻo pīhoihoi a kaumaha, uunu nui, nawaliwali, pōniuniu, eha ma ke poo. Adverse hanana manaoia e ia i allergic NaI. Ka hopena maikaʻi reactions ia ka hoʻohana 'ana i ka lāʻau "MabThera" aʻo i rhinitis, pharyngeal edema a olelo, pokole o ka hanu, bronchospasm, itchyʻili, haʻahaʻa kino ke kaupaonaʻana, no ka kāna hana o ke ono, tremors, ole, kuni, eha ma ka'ā'ī wahi, a ma ke kahua o kaʻeho IIeEeAIEUAA, i ka ulu ana o ka herpetic nā mea palahēhē.

laʻau heluna

Ka lāʻau 'Ua lawelawe ia e lohi intravenous infusion. I ka monotherapy ua hoʻohana 'ia i kekahi manawa, i ka hebedoma ma 375 mg no eha pule. I ka loiloi mua ana o ka hooponopono mua o ka 50mg / h. Mahuahua no ka i kā mākou (400 mg / h) pono e gradual kōmi.

Cautions

He kanakolu i kanaono minuke mamua e aaieieno? Paipai premedication (la hoomalolo) me analgesics a me antihistamine ai '.

Iloko o ka Inc, a me loko o na malama he umi ma hope pono hoʻohana i ka pau 'ana o nā wāhine o ka hanau keiki ana elemakule ike loea contraception.

Antihypertensive ai 'E e nōʻoe, ma ka liʻiliʻi loa he umikumamalua hora mua hooponopono o ka lāʻau "MabThera".

'Aʻole i hoʻokumu hopenaʻoi loa a me ka maluhia o ka lāʻau i loko o nā keiki.

Ma ka la hoomalolo "MabThera" loa mai ka poe akamai i ka hapanui maikaʻi. No hoi, ma o ka holo ana o ka hoʻokolokolo 'ana i, ka mea i loaʻa i ka koke koho o ka lāʻau' like me ka monotherapy, e like me ka mea hope pono o ka mea me he kākoʻo 'o ia hoʻi no nā makahiki emi ka pahiki o worsening o follicular lymphoma.