'O lymphoma follicular: nā hō'ailona, nā kumu, ka lā'au ho'omalu. 'O ka manawa o ka ho'oku'u a me ka ho'iho'i'ana o ka lymphoma follicular

Lymphoma kapaia he maʻi ia e loli ai i ka lymphatic'aʻaʻa. I kēia hihia, ho'omaka nā lymphocytes e pāpālua i ka māhele ikaika a ho'onāukiuki i nā hemahema ma ka hana ma'amau o nā'ōpū o loko o ke kino kanaka. Kaʻawale pūʻulu na maʻi: Hodgkin ka maʻi (a no laila, i kapaʻia- Hodgkin ka maʻi) a me ka 'ole-Hodgkin ka lymphoma (me follicular ole-Hodgkin lymphoma).

'O ka Lymphatic pūnaewele. He aha ia?

'O ka māhele o ka pūnaewele o ke kino o ke kino,'o ia ka lymphatic,'o ka hana nui'o ia ka pale ma nā'ano ma'i like'ole a me nā ma'i'ē a'e. 'O ia ke kikowaena o nā kaha e holo ai kahi wai kūmole - lymph. Ma ke'ano o nā capillaries, mālama'ia nā līpī lymph, kahi e ho'onui'ia ai ka lymph e nā pūnaehana kūikawā - lymphocytes. Nui nā'āpana. 'O nā B-lymphocytes ke kuleana o ka loa'a'ana o ka ma'i kūpono i nā ma'i'eha. Ma ke kākā'ana i kahi microorganic pathogenic, ho'opau lākou i kona hopena a mālama'ia i loko o kona ho'omana'o. He mau mea ko'iko'i nui ka B-lymphocytes i ka ho'okumu'ana i ka hopena o ka pale'ana. 'O ka hapa nui (80%) o ka lymph'o T-lymphocytes. 'O lākou ke kuleana no ka luku'ia'ana o nā mea'ino a pau, ka bacteri. Loa'a nā lymphocytes NK i kahi li'ili'i (e hiki i ka 10%). 'O kā lākou hana nui,'o ia ka ho'opau'ia'ana o kā lākou mau pūnaewele pono'ī (e like me ka ma'i e like me lymphoma follicular).

Pehea e ulu ai ka hana'ino i loko o ka pūnaehana lymphatic

Ho'omaka ka ho'omaka'ana o ka'ōnaehana tumomona i nā pūnaewele o ka pūnaehana lymphatic (B-lymphocytes). 'O ka ma'i i loa'a i ka po'e kahiko, i nā keiki e kū ana i nā mea kūwalewale. Loa'a ka inoa o ka lymphoma follicular i ka inoa o ka'ōpiu lauoho. Nānā pinepine'ia nā neoplasms ma ka'ā'ī, kālepa'ole, ka u'i. 'O kahi'ano o kahi lymphoma pēpē,'o ia ka mea e noi nui ai nā po'e noi i ke kōkua. Hiki i nā lymphocytes ke komo i loko o nā'ōpū a pau, e hō'ino i kā lākou hana. 'Oiai'o ka lymoma iiia ka mea ma'alahi i ka lā'au,'o ka hō'ailona o ka hopena,'a'ole ia he ala kūpono e pale aku ai i ka ma'i.

Nā kumu o ka ma'i

'A'ole hiki i nā'ike ke koho i nā kumu kūpono e kōkua ai i ka ho'omohala'ana i nā ma'i o ka lā'au. Eia nō na'e, he nui nā'ano e ho'onui i ka hiki o ka ho'onohonoho'ana i nā hō'ino. 'O kekahi o lākou ka ho'ololi'ana o nā mo'o, chromosomes. 'O ka hana ma nā hopena kūpono, hiki i ka pilina pa'a me nā mea kino'eha ke hiki ke lilo i mea ho'oikaika no ka ho'onui'ana i kahi kūlana e like me ka lymphoma follicular. 'O nā hopena o kēia ma'i e hiki a me ke'ano: ka wehe'ana i ka radiation, ka palupalu'ana o ke kino, nā ma'i autoimmune. Ho'omaopopo kekahi po'e kaumāna i nā mea like'ole e like me ka pume'ana, lawe i kekahi mau lā'au, a me ka nui.

'O ka Symptomatic o ka lymphoma

'O nā hanana lymphoma li'ili'i he mau mea palupalu loa ia, ma kahi o nā kau mua. 'O ka mea mua, hiki iā'oe ke'ike i kahi ho'onui iki'ana o nā hanana lymph. Eia na'e, ua nele lākou. He mea ma'alahi ke hā'ule'ana i kahi pu'upu'u li'ili'i, a laila'ike hou'ia. 'O kēia mea'oia'i'o, he mea weliweli loa ia. Ho'onui'ia nā pū i loko o ka sternum. Ma waho, hiki ke hō'ike i ka hekū, ka hanu o ka hanu. Hiki ke wili iki i ka maka. I kekahi mau hihia, ua pilikia ka'ōpū. 'O nā hō'ailona lymphoma li'ili'i e hiki ke loa'a a ma'alahi loa: ka make kaumaha, ka luhi nui, ke kino nāwaliwali. Eia na'e,'o kēia mau hi'ohi'ona he mea'ē a'e ma mua o ka rula, aia wale nō i kahi ma'i ho'okahi i'umi. 'O ka'oi aku o nā kūlana ko'iko'i o ka ma'i i'ike'ia e ka hā'ule'ana o ke pūpū pūpū, e pili ana i ka iwi o ka iwi. I kēia hihia, hiki i ka'ākau, ke kaua, a me ka nalo o ka'ike.

'O ke kūlana a me ka pae'ana o ka papa kula

Nui nā'ano lympho. 'O ka mua, he follicular. 'O 75% ka helu o nā follicles. Inā ma waho o ka 25-75%, he mau lālā follicular-diffuse. I loko o ka'ano ho'olaha, emi'ole he 25% o nā folo. 'O ka lymphoma follicular (iiia) e loa'a i nā hanana. Ma ke kumu mua, ho'okahi wale nō wahi o nā lymph nodes e pili. 'O ke'ano hope'elua,'o ia ke'ano o ka hana'ana i ka hana hana'ole o nā'elua a'oi aku paha o nā pūnaewele (akā ma kekahi'ao'ao o ka diaphragm). Ma ke kēkelē'ekolu, e ho'opilikia'ia nā'ao'ao ma nā'ao'ao'elua o ka diaphragm. 'O ka hāhā o ka manawa lō'ihi. Ho'ololi i nā'ōpū a me nā pūnaewele (ka momona o ka iwi, ka hānai, a pēlā aku). I kekahi manawa, ho'ohui'ia nā leka A a me B i ka helu ho'ohālike o ka wā o ka lymphoma. Hō'ike kēia i ke'ano o ka lymphoma follicular i nā hō'ailona o kēia mau mea: "B" - he loli o ka mahana o ke kino (ka ho'onui'ana o ka manawa), ke kaumaha o ke kaumaha, ka wela'ana i ka pō. 'O Lymphoma me prefix "A" -'a'ohe kahi o kēia mau hō'ailona.

Ke'ano'ike o ka lymphoma

'O ka mea mua, he kanaka lapa'au (onco-hematologist) ke alaka'i i ka nānā'ana i ka mea ma'i. He OAXA histological ninaninau o ka hāpana. No kēia mea, hana'ia ka biopsy. Lawe'ia kahi'āpana o ka puka lymph i pāpā'ia a nānā'ia ma lalo o kahi microscope. He mea pono e'ike i nā'ano o nā ma'i ma'amau'ekolu, e pono ai nā hō'ailona'ē a'e. 'O ke'ano mua e hō'ike'ia ma ka hiki'ana o nā centroblasts he elima ma ka māhele o ka nānā'ana i ka microscope,'o ka lua - he 15 mau pūnaewele. 'O ka lua o ka'ōmole e koi aku i kahi mea ho'onāukiuki, no ka mea, he mea pa'akikī. 'O ka lymphoma laulima 3a o ke'ano o ke'ano o ke'ano o ke'ano o ke'ano kolokolo. Ma ka māhele o ka'ike o ka microscope, hiki i kekahi ke'ike i nā neoplasms nui. Eia hou, pono ka mea ma'i e hā'awi i ke koko (oncomarkers,'ike nui), e'ike i nā mea o loko, CT a MRI paha. I mea e ho'oholo ai i ka hopena o ka'ōpena pūpū, e ho'olālā'ia kahi ohe'elepili no ka ho'okolokolo hou'ana no ka hiki'ana o nā pūpū ma'i.

'O ke lymphoma follicular. Hana

I ka wā ma mua, ua ulu nui ka helu o nā ma'i me kahi ma'i like'ole. 'Oiai, hiki ke'ike'ia nā neoplasms ma mua,'o ka'oi a'e o ka mea i loa'a i ka mea ma'i ke mālama i kona olakino a ola. 'O ke'ano o Lymphoma i kahi ala'ele'ele, no laila, i kekahi mau kumu, koho nā kauka e kali a'ike i nā loli a pau o ke kino o ke kanaka. No ka'oia'i'o,'a'ole e hala nā māmā a me nā hana pākīpika me ka'ike'ole'ia a loa'a nā'ao'ao'ao'ao'ole. 'O ke kala'ana o ka lymphoma follicular hiki ke ho'opane'e i nā makahiki he nui. Inā ho'omaka ka holomua o nā ma'i'ele'ele, pono e ho'okō koke'ia kerapy. Ma waena o nā'ano nui o ka mālama'ana, e ho'oka'awale'ia ka irradiation, chemotherapy, nā lā'au. Ma muli o ke'ano o lymphoma, hiki i ka ākea ka'ākau ke pale i ka hiki hou. I ka manawa mua o ka ma'i, ua kākau'ia nā kala kala lō'ihi i ka hapanui o nā ma'i.

Ke alaka'i nei i ka chemotherapy

'O ka chemotherapy pā'ani (ma ka ho'ohana'ana i nā lā'au lapa'au) i ka ho'omaka'ana o ka lymphoma hiki ke emi i ka likelike o ka ho'i'ana. No ka manawa lō'ihi, ua no'ono'o'ia ke'ano o ia'ano i ka mea nui i ka mālama'ana i nā ma'i le'ale'a. Ho'olālā'ia kā Chemotherapy i ka luku'ia'ana o nā pūpū tumora i ka manawa o kā lākou hānau. Ho'ohui'ia nā lā'au lapa'au e hiki ke ho'ololi i ka papa hana ho'oku'u i nā papa like'ole, no laila,'oi aku ka maika'i o kā lākou noi. Eia nō na'e, he hopena'eha ka hopena o ka chemotherapy ma nā mea'ē a'e ('ili, lauoho, a pēlā aku). Loa'a i kēia mau lā'au lapa'au a me ka momona o ka iwi. I ka wā o ka ho'onā'au, hiki i ke kanaka ke ma'alahi i nā ma'i ma'i, hiki i nā ma'i he nui, a me nā kahe'ana. I ka manawa pinepine,'o ka ho'omalu'ana i nā lā'au lapa'au e ho'onui'ia ka hana'ana o ka waikawa uric, kahi e alaka'i ai i ke kūkulu'ana i nā pōhaku'ōki'i. Eia na'e, e pau nā hopena'ao'ao ma hope o nā pule he mau pule ma hope o ka hopena o ka papa. He mea pono ke ho'omaopopo'ana i kekahi mau lā'au lapa'au lā'au e hiki ai ke ho'emi i ka nui o ka sperm i nā kāne, e ho'onāukiuki i ka'ike'ole o nā wāhine.

Ho'oma'o'ia me nā'elepona monoclonal

Follicular lymphoma ua ia, a me na mea hou ai 'e like monoclonal nā mea'aʻaʻa. Ho'opau kino lākou i nā pūnaewele wale nō o lymphoma. 'O kēia'ano hana maika'i loa e like me ka chemotherapy. 'O nā'epopa o ka Monoclonal e ho'ēmi iki i ka'awa'aha o nā kinikona. I loko o nā ma'i, ua mālama'ia kahi kalahala lō'ihi o ka lymphoma follicular. I kekahi mau kumu, hiki i ka hopena pa'akikī ke hiki, no laila, no ka manawa lō'ihi e hiki ai ke ho'oponopono mua'ia o nā mea'eha. Ma mua o ka ho'omaka'ana i ka lā'au ho'omalu, pono kahi ma'i e ho'ohana i nā lā'au hō'ailona.

'O ke ola o ka ma'i

'O kēia ma'i i hō'ike'ia e ka holomua iki i ka ho'omaka'ana o ka wā, hiki i ka manawa o ke kala kala ke hiki i ka 20 makahiki. 'O ka lohi ma'amau o ka lymphoma follicular i'ike'ia ma 3a'ano cytological. Ma keia hihia, oe e pono anei i ke kelepona hele transplantation. Hiki i ka mea hā'awi ke lilo i kaikunāne a me ka pili i'oki poepoe'ole'ia. Hana'ia ke ka'ina hana no nā po'e ma'i i'oi a'e ma mua o 70 mau makahiki i pane maika'i no ka loiloi'ana a no ka ola maika'i. Ma hope o ke kāpili'ana,'ike'ia nā mea hou ma kahi o ka hapalua o nā ma'i. Noho ka ola o nā ma'i ma muli o nā kumu he nui. 'O ka mea mua loa,'o ka pae o ka ma'i, ke'ano o ka ho'ololi ('a'ole loa ka maika'i o ka pronostic lymphoma follicular i ka hā o ka manawa). Pono e ho'omaopopo'ia e'oi aku ka maika'i o nā'ōpio e mālama i kēia ma'i. He mea nui ka ho'omaopopo'ana i ka lymphoma i ka manawa, no laila, mai ha'alele i nā ho'okolo hana palekana mai nā papahana.