Sertoli aeee (sustentotsit): kuleana pili i

Nā luna kuleana no nā'ōlelo i loko o nā kānaka, i kapaʻia ka testes. Ka mea, i hua mai la i ke keka keena - sperm a me hormones, e like me testosterone. Ke anatomical a histological 'ole o testes i kane eiiieaen, e like me kēia mau kino e lawe mai kekahi mau hana. Ka mea, lawe aku la spermatogenesis - ke kahua a me ka hoʻomohala o germ keena. hoʻi i hana endocrine kuleana pili i. Ka mea, i ke aupuni 'i loko o ka kūikawā kieke cutaneous - scrotum. Aia ua mālama 'ia kekahi kūikawā wela, i mea iki haʻahaʻa ma mua i loko o nā māhele o ke kino.

Testes i elliptical kinona, kā lākou nui mea ma kahi o 4 knm loa, a 3 ka laula. Maʻamau, aia i e kekahi hōʻemi iki asymmetry i loko o ka gonads. Kēlā me kēia hua manu iwi Ua puunaueia ma i pohā i ka ai iiiaanoaa o slices. Ka mea, aia no iloko olaila na convoluted seminiferous Canal ho okumu i testicular plexus. Kona efferent ducts komo i ka epididymis. Aia ua hana i ka bulk o sperm - poo. Hope - i me kaha ma ka vas deferens, a ua hoouna mai ai i ke bladder. Eia, e hoʻonui, a komo iloko o ka 'ē aʻe hui, o ka mea kane reproductive'ōnaehana - ka prostate. Ma mua o kēia, i ka wai ua hanaʻia i loko o ka ejaculatory leki uea, a ua loaa he mākeke i loko o ka'āina o ka urethra.

Histological 'ole o nā hoʻi i loko o nā kānaka

Male gonads komo o spermatic kaula, a me ka interstitial'aʻaʻa. Mawaho o ko lakou mau poi albuginea. I ua poe e anuanu connective'aʻaʻa. Albuginea spliced me ke kino. ʻaoʻao o ka mea thickens, e hana i ka mediastinum testis. Ma keia wahi, i ka connective'aʻaʻa ua puunaueia i ka ai iiiaanoaa o ka makalii. Ka mea, nāna i hana i nā lobules loko i nā convoluted tubules. Ka mea, i na poe ma ka hahai mall huahelu:

1. Sertoli keena - sustentotsit. Together a me ka mea'ē aʻe hehee wale komo i loko o ke kahua o ke koko-testis ke'ākeʻakeʻa mai.
2. Keena, ma i ua lawe spermatogenesis.
3. Myofibroblasts. Lākou nā inoa - peritubular keena. O ka papa kuhikuhi hana o ka myofibroblast - mea e hōʻoia i ka paipai 'ana o ka seminal loli o crimped kaha.

Eia hou, i ka 'ole o ka hua i interstitial'aʻaʻa. He ma kahi o 15%. Interstitial'aʻaʻa ua poe e hehee wale e like me Leydig keena, macrophages, capillaries, a no laila, ma luna o. D. Inā ka convoluted kaha i kuleana no ka ho okumu ana o ke keka keena, aia no i ke kahua a me ka? Iecaianoaaiiie o kane hormones.

Sertoli aeee: 'ole

Sertoli aeee i ka elongated shape. Lākou nui mea ma kahi o 20-40 microns. He He 'ano mele mall naehana i ka mea okoa i kapaia kākoʻo keena. Ma ka cytoplasm o kēia mau keena na nui organelles. I waena o lākou:

1. Kora. He mai he ole, i kekahi manawa - ohia-hoʻokino. Ke chromatin i loko o ka nucleus ua haawi unevenly.
2. Malimali a me ka apuupuu EPS. Ka mua - He kuleana no ka? Iecaianoaaiiie o steroid hormones, i ka lua o ka - e hoʻolako kumuʻiʻo hoʻololi kemikala.
3. Golgi i hoʻomākaukauʻia. Mahalo i kēia organelle, aia no he hope hoʻololi kemikala, pūnaewele a me ka wehe 'ia o nā huahana.
4. Lysosomes - e hoʻomau ana ma ka phagocytosis.
5. Microfilaments. Mau organelles i komo i loko o ka maturation o sperm.

Eia hou kekahi, kēlā halepaahao he Sertoli momona inclusion. Sustentotsitov kumu ua aia ma luna o nā paia o ka seminiferous tubules, a me ke kihi - helehelena i loko o kā lākou lumen.

Sertoli aeee: kuleana pili i

Sertoli aeea o kekahi o na eiiiiiaiou ho okumu i ka convoluted seminiferous tubules. Ua mea o ka nui, e like me ka mea i komo i loko o ke kaʻina hana o ka spermatogenesis, a me ka hoʻololi kemikala o kāne hormones. Aia nō i ke kēia hana o Sertoli aeee:

1. Trophic. Mau kumu mua iʻiliahi sperm keena me ka o oxygen a me ka mahuaola.
2. Aiiay. Kēlā me kēia aeea i ka cytoplasm lysosomes - organelles limahana ma phagocytosis. Hoʻokemu a recycle i ka decomposition nā huahana, no ka laʻana, hakina o ka make spermatids.
3. Hoomanao e ana i ke koko-testis ke'ākeʻakeʻa mai. He kuleana pili i ua lako pono e kokoke aeea-aeea ihe. Ke'ākeʻakeʻa Ua pono, e hookaawale i ka kane anal keena, mai ke koko, a me ka waiwai i kakauiaʻi i loko o laila. Eia hou, e ālai 'ia' o ka anal o sperm antigens ma ka wai koko. Kēia ho'ēmi i kā ka pilikia o ka ulu autoimmune li nui.
4. Endocrine kuleana pili i. Sertoli aeee i komo i loko o ke kahua o ke keka hormones.

Sustentotsity pono no ke kahua a me ka malama ana o ka kūikawā 'ia i loko o i sperm hoʻomōhala pono maoli nō. Ua ua ike ia ka ionic haku mele 'ana o Sertoli aeee mea okoa, mai ke koko wai koko. paʻakai lehulehu o lalo, a he potasiuma maʻiʻo, ma ka mea ku ole, mahuahua. Eia kekahi, ma Sertoli keena synthesize nui biologically hana waiwai. Iwaena o lakou - na prostaglandins, cytokines, follistatin, ulu kumumea a me ka puunaue, opioids, a pela aku ...

Launch a me ka 'ole o Leydig keena

Leydig aeee i kuleana testicular interstitial'aʻaʻa. Lākou nui mea ma kahi o 20 microns. Ke kane gonads, ua oi aku mamua o 200 * June ¹⁰ Leydig keena. Ke mall hiʻona o kēia mau kumu mua mea he nui ka'ololaha nucleus a me ka foamy cytoplasm. Ua he vacuoles i loaʻa ka kumuʻiʻo lipofuscin. Ua ua hana ma ka hoʻopöʻino 'ia o nā bipi kūpaluʻia i loko o ka minute o ka hoʻololi kemikala o steroid hormones. Eia hou, ma ka cytoplasm i 1 a me 2 nucleolus i loaʻa ka RNA a me ka kumuʻiʻo. O ka papa kuhikuhi hana o Leydig keena - ka testosterone. Eia hou kekahi, ka mea i komo i loko o ka hoʻololi kemikala o activin. Kēia waiwai stimulates ka? Iecaianoaaiiie o FSH i loko o ka lolo.

He aha ka ka Sertoli halepaahao maʻi pale?

Kekahi o ka mea pohihihi keia maʻi o ke kane reproductive'ōnaehana o ka Sertoli halepaahao maʻi pale. I ka papa kuhikuhiE hoike ana o keia maʻi ua noʻonoʻo i ka infertility. I ka maʻi ua pili i ka congenital anomalies, no ka mea, ua malama aplasia (he nui ka ho'ēmiʻana a me ka wa e kaawale aku) o embryonic testicular'aʻaʻa. E like me ka hopena o keia nahae o seminiferous tubules hoʻomōhala. Ka wale hehee ai i ua ole poino - o ka Sertoli halepaahao. Kekahi inoa no keia maʻi - he maʻi pale del Kekahuna. Part o Sertoli keena nō undergoes degeneration, naʻe, ka hapanui o ia - e maʻamau. I loko nō o kēia, i ka epithelium o na tubules atrophied. Spermatozoa ma keia pathology ka mea,ʻaʻole i hanaʻia.

Hoʻopilikia o ka hana o Leydig keena

Inā ka poino Leydig keena Nyos lākou iniiaiie kuleana pili i - testosterone hoʻololi kemikala. E like me ka hopena, symptoms e like me:

1. Hoemiia Muscle nuipa.
2. Wa e kaawale aku o ka haumāna ke keka ano (ulu o ke kino lauoho o ke kane type, leo).
3. 'Aʻe' ana o libido.
4. Ua hoʻemi iwi nuʻa.