Glycogen. He aha ka mea? E ka loaʻa mai!

Glycogen mea he luna, he luna 'carbohydrate, a ua hanaʻia i loko o ke kaʻina hana o ka glycogenesis monakō koko kino pu me ka ai. Mai ka Nine Inch wahi o Hawaii ka mea, ua nānā 'ia e ka haʻilula C6H10O5, a ho colloidal polysaccharide me ka lahui manamana ai lei o ka monakō koko residues. Ma keia 'atikala, e hai aku mākou a pau e pili ana i ka glycogen: mea ia mea, i ko lakou mau oihana e, kahi a lakou e stocking mai. No hoi, mākou e wehewehe i ka mea i ka deviations ma ke kaʻina hana o ka synthesizing.

Glycogen: He aha ia mea, a pehea ka mea, e synthesized?

Glycogen o ke kino pono monakō koko me ke koe. Ma kānaka ka mea, ua synthesized like penei. Ka manawa e carbohydrates (me pia, a disaccharides - lactose, maltose a me ka sucrose) ma lalo o ka hana o ka'ūhū (amylase) e Wāwahi i loko o liʻiliʻi nā lātoma. A laila, ma ka liʻiliʻi liʻiliʻi nā'ūhū e like me sucrase, maltase a me pancreatic amylase hydrolyzing ka carbohydrate residues i monosaccharides, me monakō koko. Kekahi hapa o ke kala o ka monakō koko, komo i ke koko, a hiki i ke ake, a me ka mea 'ē aʻe ua kaʻi aku i loko o na keena o ka'ē aʻe nā loko. 'Ana i na keena, a me Muscle, aia no he hope hoʻopöʻino' ia o ka monosaccharide monakō koko, a ua kapaia glycolysis. Ma ke kaʻina hana o ka glycolysis, a ia lŘlŘ me me ke komo 'ole (aerobic a me ka anaerobic) i oxygen e synthesized ATP lātoma, a mea he kumu o ka ikaika i loko o nā meaola e noho ana. Akā,ʻaʻole i ka monakō koko e komo i kaʻai i loko o ke kino o ke kanaka, i hoopauia ma ka hoʻololi kemikala o ATP. Part no ka mea, ua waiho ia ma ka palapala o ka glycogen. Ke kaʻina komo ai i ka polymerization o glycogenesis, a laila ka sequential hou o ka monakō koko i kekahi i kekahi, a monomers ho okumu i ka manamana ai kaulahao polysaccharide ma lalo o ka aoao o ka ho'ākāka 'ia i nā'ūhū.

Auhea ka glycogen?

Waiho waho glycogen loaa ma ke ano o ka hana i ho'ākāka 'granules i loko o ka cytoplasm (cytosol) na keena o ke kino. No kiʻekiʻe maʻiʻo o ka glycogen i ake a me ka Muscle'aʻaʻa. A me ka Muscle glycogen - he kumu o ka monakō koko kumukūʻai no ka hapanui Muscle aeee (i loko o ka hihia o ke kaumaha e haawe), a me ka malama maʻamau hepatic koko monakō koko lehulehu. E like me ka hoolako ana i mau luna 'carbohydrates i loaʻa i loko o ke aʻalolo keena, naau, aorta, epithelium, connective'aʻaʻa, ka mucousʻili lahilahi o ka uterus a me ka fetal'aʻaʻa. No laila, nānā mākou i ka mea i manaoia ma ka makahiki "glycogen". He aha ka mea, kēia manawa ia mea kālaʻe. Next, e ka kamailio e pili ana i kā lākou mau hana.

He aha ke kino pono glycogen?

Ma ke kino glycogen ua hoʻohana 'ia e like me ka ikehu no?. I pilikia wahi, i hiki i ke kino e kiʻi mai o ka mea nele monakō koko. Pehea ke ano o keia hana? Glycogen hālāwai hope ia lŘlŘ ma waena oʻai, akā, no hoi me ka nui loa hōʻeleu i ka wa loa physical hana. Kēia kaʻina ia lŘlŘ ma cleavage o ka monakō koko residues ma lalo o ka aoao o kūikawā nā'ūhū. E like me ka hopena, glycogen decomposes i noa monakō koko a me ka monakō koko-6-posapahate o ATP me na koina.

No ke aha la oe i pono ai ka glycogen i loko o ke ake?

Ke ake nei kekahi o na mea nui kipi nā loko o ke kanaka kino. Ua hanaʻia he ākeaʻano o ka nui i hana '. Including hoʻolako maʻamau koko kō pae, He pono no ka lolo functioning. I ka papa kuhikuhiE maomeka ana a e malama i monakō koko i loko o ka maʻamau huahelu - mai ka 80 a hiki i 120 mg / e hahai ma decomposition o lipogenesis glycogen gluconeogenesis a me ka hou 'ana o nā pulapula o ke, e monakō koko DL. Ma ua hakumakuma i ke koko kō pae haʻalele no phosphorylase, a laila, ua pipili ake glycogen. Mai ka cytoplasm o aeee nalo o kana poe hipa, a me ka monakō koko komo i ke koko, e haawi ana i ke kino o ka pono ikehu. Ma ka 'ilikai ai oi aku o ke kōpaʻa, no ka hana ma hope o kaʻai, ake keena hoʻomaka i ka' Imi synthesize glycogen, a, e waiho ia. Gluconeogenesis mea he kaʻina hana o ka synthesizing monakō koko, mai ke akepaʻa, a hiki i nā waiwai, a me'amino nāʻakika. Ke hoʻokonukonu hana o ke akepaʻa ʻo ia ka mea, o loi e pono ai no ka maʻamau kino functioning. Haiahū kūmau - he nui mahuahua / emi i loko o ke koko monakō koko pae - ho i ka pilikia nui i kanaka ola.

'Aʻe' ana o glycogen hoʻololi kemikala

Metabolic kāna hana mau i ka pae o ka glycogen glycogen hereditary maʻi. Kā lākou mau mea, lalau mai e likeʻole mā nā'ūhū pili 'ole i loko o ka rula o ka glycogen ho okumu a cleavage. I waena o glycogen maʻi, a kaʻawale glycogenoses aglikogenozy. Ka mea mua o ka pohihihi keia ili maʻi, kena ae la ia e ka excessive hoʻomāhuahua o ka polysaccharide ma C6H10O5 keena. Glycogen hoʻololi kemikala a me kona mahope excessive alo ma ka akepaa, akemāmā, hakuʻala, skeletal Muscle a me cardiac mā, kena ae la ia e'ūhū (e laʻa me, monakō koko-6-phosphatase) komo i loko o ka hālāwai hope o ka glycogen. Loa pinepine, ka wā glycogen kino malama aʻe 'ana o ka? Acaeoey, psychomotor retardation, loa hypoglycemic moku'āina, i hiki i ka hoouka kaua ana o coma. E hoʻokūpaʻa i kaʻike, a me ka hooholo i ka 'ano glycogenosis lawe biopsy ake a me nāʻiʻo, a laila, hoʻouna aku i ke kūpono i nā puke i histochemical mahele. I loko nō o kona 'ia paha glycogen maʻiʻo i loko o nā'aʻaʻa, a me ka ha awina o nā'ūhū e hoʻonui i kona hoʻololi kemikala a me ka hoʻololi iho.

Inā i ke kino o ka wahi me ka glycogen, mea 'aʻole ia ke ano o?

Aglikogenozy ho nui hereditary maʻi kena ae la ia e nele i ka'ūhū hiki ia oe e lawe mai i ka hoʻololi kemikala o glycogen (glycogen). Ma ke alo o keia maʻi i loko o ke akepaʻa glycogen mea pau kahi e. Lapaʻau hoike ana mai o ka maʻi i: loa haʻahaʻa koko monakō koko, ai - ikaika hypoglycemic ke kāʻili 'ana. Ke ano o nā mea maʻi ua hoakakaia like loa hoʻoponopono. Ke alo aglikogenoza hookolokolo aku la ia ma ka hali ana mai i ka ake biopsy.