Ka hōmona 17-OH-progesterone. 17-OH-progesterone: o ka uku o ke koko

I ka papa kuhikuhiE AIM o ka hormonal kalapona i loko o nā wāhine i ka menstrual kalapona - ovulation. I loko o kēia kaʻina hana, ia mea ma lalo o ka mana o ka hypothalamus. Ma keia hihia, i ka waiwai na na huahana mea e pee ana ma ka anterior pituitary gland: FSH a me ka LH.

ho okumu ana o ovulation

I ka mālama '-ovulatory pae o ka menstruation kalapona ovarian follicle undergoes kekahi mau loli'. Mau loli e lawe wahi ma lalo o ka aoao o FSH. Ma hope o ka follicle kīnā i kekahi nui, e like me ooieoeiiaeuiiai haʻawina i loko o LH ovulatory piko ua hana. Kēia e ho'āla ai i ka "maturation" ovum (ka mua meiotic mahele). Ma hope iho o kēia pae discontinuity ia lŘlŘ i loko o ka follicle kahua, a me ka mai ma i ka hua. I ka wā mawaena ma waena o ka piko a me ka ovulation pae o ka mea o 36-48 hola, Ma ka postovulatory pae pohupani hale ia lŘlŘ nō kāu hua a hiki i ka uterus o ka fallopian Tube. Ma ka hihia o ka fertilization i ke kolu-hā o ka lā o ka embryo komo i loko o ka uterine lua. Aia o kona implantation. Inā fertilization i ole ana, alaila, o ka hua manu i ka lā e make i loko o ka fallopian Tube.

Waiwai 'ole i loko o ka hiki' ana o ka wahine reproductive kuleana pili i

Ma ka endocrine glands i hanaʻia o ka biologically hana i huiʻia. Ka mea, i kapaʻia hormones. He mahalo iā ia ma nā hypothalamic-pituitary-ovarian'ōnaehana a kaulike he mea ikaika haʻawina o reproductive nā loko. Kēlā me kēia hui hanaʻia kekahi mau hana. Kekahi o ka waiwai 'ole i loko o ka keʻano o ka hanaʻana i loko o ka reproductive nenoaiu, he 17-OH-progesterone. Follicular pae kahe ana me ka nui mahuahua i loko o kona lehulehu. Kēia hui Ua synthesized ma ka meaʻuʻuku i loko o ka ovary. Mahuahua ka maʻiʻo o ka waiwai o ka piko kahua o ka pH. Mahope, ma ka waena o ka pōʻaiapuni, ua hoemiia ka lehulehu no ka pōkole wā. Progesterone i loko o ka follicular pae 'aʻole hoʻi endometrial ka hoʻonuiʻana hauma¯na ma estrogen. Ke kūpono i huiia Ua malalo i ka loli. I ka papa kuhikuhiE kumu o ka menstruation o ka ulia cessation o? Iecaianoaaiiuo ma ke kino luteum progesterone kalapona paʻaʻana. Uaʻimi hoʻopunipuni palena manawa no ka luteal pae endometrial stroma hana decidual naoh. Ua mea i 'ano like me na mea hou likeʻole wahi i ka hoʻomaka o ka hāpai keiki. Progesterone i nā rula o glands i loko o ka cervix, emi contractility lua. Ke hui pū inhibits menstruation.

Ka hōmona 17-OH-progesterone. hōʻikeʻano

He ka precursor steroid. Ia mea adrenal cortisol i hanaʻia ma lalo o ka aoao o nā'ūhū e like me 11-b. 21-hydroxylase paha hydroxylase. 17-OH-progesterone i loko o nā wāhine hiki synthesize androstenedione. Kēia mea He He precursor o testosterone a me ka estradiol. Ua ua hana ia ma na ovaries a me adrenal glands. I ke koko progesterone-17-OH makana i loko o ka noa, a nakinakiia, me ka lawe nā polokina like transcortin a me ka albumin. I ka wa e kaawale aku o ka fertilization waiwai lehulehu emi iho. Ma ka hihia o implantation o ka hua manu i loko o ka ovaries, ke kino luteum mau e paka ia.

lehulehu

17-OH-progesterone hoʻomāhuahuaʻoe i loko o ke kakahiaka. Palena iki kona Contents hoike mai i ka po. Iloko o ka lā, konaʻilikai loli aʻe. A me ka hui lehulehu loli aʻe i loko o ka menstrual pōʻaiapuni. A nui mea ulu i loko o kaʻilikai nānā i ka lā mua o ka LH piko. Keia ua ukali ma ka pae ana i kā mākou lehulehu (hapalua like-pōʻaiapuni). Ma hāpai keiki, waiwai maʻiʻo ua me ka nui loa mahuahua. 17-OH-progesterone, o ka uku o ka i me ka nānā 'ia e like me ka makahiki o keiki ua iloko o loko o ka uuku dala. Nui nā hoʻohui like i loaʻa wale nō i loko o ka momona manawa, a mahope koke iho o ka hanau ana. Ma keia hihia, ma premature na kamalii uuku ka maʻiʻo, kŘpa a nui. Iloko o ka hebedoma mua o ka pilina pae Falls. Ua kaulana kekahi e holumua ai mahuahua i puberty. I loko o kēia wā, progesterone-17-OH adolescents ke kiʻekiʻe o ka ia lehulehu like i loko o nā mākua ihoiho.

No ke aha la oe i pono ai i ka koko hōʻike?

17-OH-progesterone He palapala huahana. Eia naʻe, i kona study mea nui i koe i loko o kaʻike, o like pathologies. Ma ka hoike ana o ke ao nā infertility, hirsutism, pōʻaiapuni kāna hana. I ka adrenal hyperplasia like me ka iapaau ana no nā mea maʻi lawelawe steroid hope Inc. E Loiloi i kona laulā Ka Ikepili ua no hoi ia. 17-OH-progesterone aʻo i loko o na kamalii uuku. Kona lehulehu like manao 21-hydroxylase deficiency. Deficiency o keia'ūhū malama i congenital adrenal hyperplasia type.

Makaukau no ka keʻena hoʻokolohua ikea ai

Inā ke kauka 'aʻole i loaʻa i kekahi'ē aʻe manawa, i ke koko, oia ke i ma luna o ke kolu o ka i lima o ka lā kalapona. Ke kuka nei lakou i mālama 'ia ma luna o ka waiwaiʻole'ōpū i loko o ke kakahiaka. Ua ua i ae i ka hana o ke kope a me kī. Ae e inu akaka ka wai. Mai ka hopeʻai mua koko donation e ia ma ka liʻiliʻi loa, ewalu hola. Poe akamai i manao ka mea kūpono 'hōmona study o ka lua o ka pae i 20-23 lā. Inā ka lōʻihi like 'ole o ka pōʻaiapuni o 42 mau lā, i ke koko hāpana ua lawe mai ma luna o ka 35 la lā. Ma ka 23rd lā o ka pae mua nō mau. Ua hoemiia ka nui o ka progesterone, akā, ka mea, aole ia e hōʻike i ka hoʻokō 'ole' ana o ka luteal pae paha anovulation. Ua i ole ano e hoʻomaka i ke ao o ka lehulehu i hāpai keiki, a, e lawe i kekahi ai '. Ma keia hihia, he kiʻekiʻe 17-OH-progesterone - ke kūmau. Oia ka maʻiʻo o prenatal malama ia i koi 'ia.

ʻano o nā hualoaʻa

I haiia ae maluna,, ka maʻamau kiʻekiʻe o ka hōmona progesterone, 17-OH hilinaʻi nui ma luna o kona mau makahiki. Nui a me ke keka o ke kumuhana. Ka lehulehu Ua nānā 'ia ma ng / ml. Pau e pono ai ka maʻiʻo no na keiki mai ana i ka mahina - 0-16,63; 1-2- mahina. - 1,8-9,7; 3 mahina. - 0,07-1,7. No nā mea maʻi ma lalo o hoʻokahi makahiki - 0-1,65; mai ka 3 makahiki - 0-0,99; mai ka 3 a hiki i 10 - 0,07-1,69. Ana 'ilikai no na kanaka - 0.5-2.1. No nā wāhine i loko o ka mea follicular pae - 0,41-2,72; ovulatory - 0,33-2,8; luteal - 0,33-2,8. Ma ka trimester mua prenatal progesterone-17-OH pono e noho i loko o ka lehulehu o ka 1,17-5,62; Lua - 1,17-6,7; i loko o ke kolu - 1,24-11. Ma postmenopausal pau e pono ai ka maʻiʻo o 0,13-0,51.

adrenal hyperplasia

He He congenital autoimmune pathology. IeAUPIIe, IAa IO e hoʻomōhala ana i like me ka hopena o ka deficiency o nā'ūhū komo i loko o ka hoʻololi kemikala o steroid. Ka nele o ka hui i i kekahi mau degere o ka oolea. Ma kona wā kamaliʻi ma congenital hyperplasia e hoʻomōhala ana i virilization (i ke kahua o ke käne kāna moʻolelo i loko o nā wāhine). I loa hoopii, he'ūhū deficiency ka hoʻonāukiukiʻana aʻe 'nui i loko o ka hoʻololi kemikala o steroid i, ka paakai poino, a hiki e ke ola-na olelo hooweliweli au. Ua loaʻa hapa deficiency o ka'ūhū i loko o nā mākua, e hiki no hoi e congenital ma ka ano. Ma keia hihia, initially 'aʻe' ana i loko o ka latent palapala, a me ka mea, e mau 'akomi i loko o kamaliʻi. Hihia hoʻi hoʻololi kemikala o nā'ūhū hiki i kekahi e holumua ai külana. Ma lalo o ka aoao o adverse pathological aʻe maoli me ka pahiki o ooieoeiiaeuiiai a me ka morphological loli ma ka adrenal glands, like hoikeana o congenital maʻi pale. E like me ka hopena o Nyos moe? Acaeoey o adolescents. Ma ka hailona ana o progesterone, 17-OH e kālele ana kona mama no hoi ma o ka hoʻololi kemikala o androgens. Mau i huiʻia ai hoʻolahaʻia i ka wā kamaliʻi, a hoʻonāukiuki kaikamahine olelo o ka 'īnea i ano o kāne type. No laila, i ke ao ana o ka lehulehu he mea nui i ka hoomaopopo ana i ka laulā o ka lapaau ana.

Ka oi mea deficiency o ka'ūhū 21-hydroxylase

Ka nele i huiia ho'āʻoʻia hoemiia aldosterone ho okumu. Kēia adrenal hōmona hoʻolako hooponopono ana o ka wai a me ka paʻakai koena, hoʻopaneʻe 'ia ana i loko o ke kino o ka paakai. Ma na kamalii uuku, aia no he "ulia poho." No ka mea, he ano wehewehe aku ma ka hoʻomāhuahua o ka loli i ka nui mea. I ka Ia manawa i ke kino, e 'Imi hookaawale ia i ka mea e pono ai ka paʻakai. E like me ka hopena, i ka potasiuma maʻiʻo hoʻomaka e mahuahua, a me ka paʻakai - hoole mai oia. Hapa'ūhū insufficiency wehewehe aku holoiia lapaʻau kiʻi. Ua ulu maila ka deficiencyʻikea au i loko o ka kāʻei kua o ka 'aʻe' ana o puberty a me ka ulu ana i loko o puberty, ma ka mua e poohina ai - me ka infertility, a hihia hoʻi i ka menstrual kalapona, na kaikamahine - me ka hirsutism.

ka hopena

I ka ha awina o ke keka hormones o kekahi o ka hoomaopopo ana kumumea e ole wale i ka functioning o ka reproductive nenoaiu i loko o nā wāhine. Ke naoh o ka hui, kā lākou kumupaʻa a me ka maʻamau haʻawina, komo i loko o kekahi keʻano o ka hanaʻana, e like me ke alo o ka a pau e pono lehulehu mai ka hopena ma luna o ka pono kūpono 'ana o ke kino a me ka ola i ka mau. Ke hoʻomalu ao aku i ka manawa a kekahi haiahū kūmau mai na hae ma ka lapaau mea i ka hoailona o ka pathology. Ma keia e pili ana, i loko o kēlā me kēia hihia ka mea, 'aʻole i koi lapaau. Eia naʻe, kauka waiho aku i mau E lūlū mai ke koko i ka keʻena hoʻokolohua Ka Ikepili, e hele examinations. maʻi kekahi i kekahi latent palapala a me ka untimelyʻike, hiki aku ai i ka mea hopena. O ka pau nui o ka moku'āina o hormonal wahine. 'Aʻole hōʻike' ia ma kamaliʻi kāna hana me ka elemakule progresses, e kauoha ana ka hoʻohuikau 'ia ma ka functioning o ka reproductive a me nā nenoai i loko o ke kino. Ma kekahi mau hihia, infertility - kekahi o ka loa ka manaʻo pilikia i keia la - o ka hopena o ka hopena oʻike. No ka hoʻomanawanui iki mai ka loaa ana hope Inc, no hoi e pono ai ka pololei, ponopono-ae la a me ke koko e ho'āʻo ai. Nā hualoaʻa ae ole wale i ka Loiloi i ka pākōlea hopenaʻoi loa o na ai ', akā, no hoi, e hoʻomaʻa kā lākou palapala noi noaia.