Ka lāʻau "Amiodarone": analogues, kauoha, hōʻike manaʻo

Heart, e like me ko oukou ike ana, mākou ka papa kuhikuhi kino, akā, ia pinepine ke aloha. I mea kona maʻamau functioning e hoihoi mai hana i kekahiʻano o ka ai '. Kekahi o ia mea "Amiodarone". Analogs ua ikaika nui ae pipiʻi, like i hua mai la i ka lono, a mau mea i kona mana.

I ka haku mele 'ana o ka lāʻau, a me ka ano o

Ka medicament "Amiodarone", a hōʻike manaʻo i ka likeʻole ma maupaʻa i loko o kekahi papa o ka 200 mg oʻeleu 'Oponopono - amiodarone hydrochloride. Ka la hoomalolo Ua i hou me ke kākoʻo pāʻoihana, kahi 3 ml ka 5% o kaʻeleu 'Oponopono.

Kākoʻo ke keʻena haku o kekahi papa e: uala pia, mea pōaka microcellulose, lactose, maltodextrin, primelloza, polyvinylpyrrolidone, makanekiuma stearate.

Nā papa uhi me ka glaze o keʻokeʻo ano me ka hōʻemi iki, maalea holika malu. Ka mea, i ka palapala o Valium a me ka facet a me Valium. Nolaila, ina he pono, ka mea, hiki wawe ke maheleia i mau like.

Uluwehi O kūʻaiʻia ma ka pepa pahu, ma kekahi a mau blisters me ka umi na papa. Ka lāʻau 'Ua i hua mai i loko o ke aniani, polymeric a me ka ea hue, a i 30 a 100 na papa.

Ke pharmacologicalʻano papa hana o ka lāʻau 'ana

Antiarrhythmic a antianginal waiwai i wehewehe aku e "Amiodarone" analogues ma kekahi hihia e puku ia ia. Kona Anati-arrhythmic ana ua ma muli o ka ka ho'ēmiʻana pono o ka potasiuma Ion ia malalo i kaʻili lahilahi keena - cardiomyocytes. It ke kumu i ka ho'ēmiʻana i loko o ka sinus wahi a 'ano apau loa bradycardia.

E ho ohana ana o ka lāʻau "Amiodarone" (huaale) ke hoʻonui i ka lōʻihi o ka refractory cardiac conductionʻano papa hana. Inhibits ka conductivity o kiʻekiʻe mau alahele i loko o nā mea maʻi me ka loa maʻi pale o Wolff-Parkinson-White maʻi pale. I huli ai oe, o ka antianginal lāʻau ia ua kūkuluʻia ma luna o hoemi myocardial oxygen ma hokii, a me ka hoemi kona hopena ma luna o ka arterial nāʻiʻo. Ua hakuʻia o ka iodine, i mea ma ka hoʻohanaʻana i laupaʻi EUIAaIN ka maʻiʻo o ka thyroid hōmona, kūpono ma ke degere o ko lākou hopena ma luna o ka myocardium ua hoemiia.

"Amiodarone" i ka huina kanawai, a me ka hai ia ma luna o kona palapala noi ia lŘlŘ ma hope o kekahi hebedoma o ka maʻamau pono o ka lāʻau wale, a ua hiki aku i ka i kā mākou ma hope o nā-ekolu pule.

Loko o ke kemu ma kahi o 40% o ka inu i ka mahele lāʻau, Cmax wai koko akaka ma hope 3-7 hora, ke hookoia mea hiki ke hoomau anei oukou no kekahi mau pule. metabolic keʻano o ka hanaʻana lawe wahiʻano nui i loko o ke akepaa, ma kaʻeleu hehee ai ua hana dezetilamiodaron, i mea no ka nui metabolite. E hoʻi me ka malū bile a me ka mimi, T1 / 2 - ma hope o ka hookahi mahele lāʻau o ka lāʻau 3,2-20,7 h, me ka hooloihi ae i Inc - ma hope o 53 ± 24 hola.

Medicine "Amiodarone": nāʻikepili no ka hoʻohana

I hoakaka ia i ka lāʻau no ka Kāohiʻana a me ka lapaʻau o arrhythmias, a hiki terminally hoohewa ai kanaka ola ana, e like me ventricular arrhythmias, ventricular kolili i lolelua kaʻano i hoʻohana lāʻau ' "Amiodarone."

Nāʻikepili ae e hoʻohana i ka lāʻau a me:

• atrial koliliʻana;
• supraventricular arrhythmias;
• Wolff-Parkinson-White maʻi pale;
• hanana o ke tachycardia;
• fibrillyatsionnogo hiki ventricles;
• arrhythmia i kupu mai ma muli o ka cardiac a me ka coronary insufficiency;
• maʻi ano o coronary naau maʻi;
• myocardial infarction.

"Amiodarone": kauoha no ka hoʻohana

Papa i manaoia no ka moʻolelo hoʻoponopono ma hope o 15 minuke ma hope o kaʻai.

Ma ventricular fibrillation maʻi laʻau heluna paipai ia e kekahi kahuna lapaau, o 800-1200 mg no ka lā. It E e maheleia i 3-4? Eaia. Ka iapaau ana i keia hihia mau no e pili ana i 5-10 lā e hōʻoia i ka paa ana o ka hoʻomanawanui i ke kikooia aku, a me ka lākiō o hiki ke kuu iho i 600-800 mg no ka lā. Kēia mālama nui lapaʻau, i a laila puka mai i kāohi, he haahaa mahele lāʻau o ka lāʻau maʻiʻo.

Pākōlea malama au mea 7-14 lā, i loko o keia manawa o ka lāʻau e lawe 200-400 mg. Oia lāʻau ka leo häʻawi mai ai iä stabilize i ke ahonui o ka ano i loko o poslereabilitatsionny manawa.

Pinepine i ka laau "Amiodarone" i koi 'ia ka wā o ka hoʻomanawanui i loko o ka haukapila, a me konaʻano hana hiki mana i ke kauka. Kēia i mea e hiki ai e kń i kaʻaoʻao waiwai a pākahi hoʻomaʻa i ka mahele lāʻau o ka lāʻau.

I ka wā o ka medicament maʻi angina hoʻohana palua i ka lā ma 200 mg. Ma hope o 'elua pule, i hoemiia ka laʻau heluna a hiki i kekahi manawa i ka lā. ʻO kā mākou hookahi mahele lāʻau mahele lāʻau e ole oi 400 mg, a me ka kela la i keia - 1200 mg.

Ma i kauoha mai ai i kēia mau ai 'ia nā keiki e ke kaʻikaʻiʻia ma ka manaʻo i ka Akala a aloha ia i ke keiki, ua nui māmā ma mua o ka makua. No laila, i ka mahele lāʻau he pōpilikia ma muli o ka ke kaupaonaʻana o ke keiki. Penei, haule 10 mg o ka medicament kekahi kilogram o ke kaupaona pono. Kēia mahele lāʻau pono e mālama 'ia ma ka pākōlea wā o na la he umi paha a ke hoʻomanawanui i ka kulana holomua. I hoakaka ia, ua hoakaka e emi i ka like ana o ka 5 mg no kilogram kino ke kaupaonaʻana o ke keiki. Kāohi malama mahele lāʻau ua ia, a me ka nānā 'ana ma kekahi kilogram o 2.4 mg o ka lāʻau "Amiodarone."

Nāʻikepili a hiki i ka lāʻau i hoakaka ia e hoʻohana i ka pāʻoihana ma muli maʻeleu 'Oponopono o amiodarone hydrochloride ma huʻi cardiac arrhythmias. Ma keia hihia, i ka lāʻau 'ua lawelawe intravenously, lohi injected me ka dropper i loko o ke kino. E hana i kēia, 250 ml o 5% monakō koko pāʻoihana no ka 1 a 2 Ua lohi injected lāʻau mahele lāʻau o ka 5 mg no kilogram kino ke kaumaha. I keia manawa, i ka hoʻomanawanui ua ua hoʻonānā ma ka mea o ECG a me ke koko, e kahaʻikepili.

ʻaoʻao waiwai

No laila, nui kuhikuhi ai ' "Amidaron" ma ko kakou aina. Analogs e hiki e puku ia mau ole. Akā, mamua o ka maikaʻi 'ole o ka lāʻau ma luna o ke kino o ke kanaka, i ua hōʻike' a me kaʻaoʻao waiwai.

Noke symptoms meaʻano nui manawa i ka lāʻau overdose. Kēia 'aʻe' ana o ka mea'ōnaehana mānowai koko oihana, e like me bradycardia, sinus wahi papa ka hoʻokō 'ole, naau aeie, make o ka ōhumu o ka neʻe. No hoi ma ka aoao o ka naehana'ōnaehana i ike eiei? Interstitial pulmonary fibrosis, interstitial pneumonia, Hamm maʻi pale - Rich, umauma eha, pulmonary fibrosis, tachypnea, bronchopulmonary spasms. Ua malama i ka wa e loaa ana "Amidaron" hoʻomākaukau Hepatic ole. Papa ma pohihihi keia hoopii i jaundice, hepatitis, cirrhosis i kekahi manawa.

Ole e hooko me ka laʻau heluna hiki i ka nui imbalance o thyroid hormones, distireoza a me ka hypothyroidism, a me ka lākou o keu i nā kilo. Overdose ke alakai i ka hoʻohuikau 'o ka pilikia makapō i hoʻomākaukauʻia, e kauoha ana i ka hoʻomāhuahua o lipids i loko o ka cornea a hiki i ka haumāna. No hoi, aia no he haʻi pigmentation o kaʻili, photosensitivity, urticaria paha erythema. Ua ike Minor rashes maka, alopecia, dermatitis. ʻaoʻao 'ole i loli ka reproductive kuleana pili i loko o nā kānaka. Ma kēia manawa he mea orchitis, impotence, a me ka epididymitis. Muli o kona kulana pohihihi thrombocytopenia,ʻaʻa puʻuwai ka hoʻokō 'ole, a me angioedema vasculitis.

Contraindications i ka hoʻohana 'ana o

"Amiodarone" (manaʻo uaʻaʻole manawa maikaʻi) ua wae pololei pākahi. Aia mau kanaka i keia k i i ke kōkua 'ole ka mea, i ole i kekahi' loaʻaʻohe loli ma ka ola you, hoomaka ae la kekahi poe e kinai iho ma hope o kou pili ia, i manao ai naau palpitations. I kā lākou mau'ōlelo, Propafenone ia mea hiki ke loko i ka endocrine'ōnaehana hormones mahuahua ai. No laila, ma mua ka lawe i kēia lāʻau lapaʻau huahana pono ole wale akahele heluhelu i ka olelo, akā, i hoʻolohe ia i nā nāʻikepili,ʻaoʻao 'ole a me nā contraindications.

Penei, pono ole e pili i ka lāʻau 'ina he mea atrioventricular aeie papa 2-3, ma cardiogenic kŰia, hyperthyroidism. E hoomakaukau ai "Amiodarone" ua i hoʻohana 'ia i loko o kona kiʻekiʻe pā lonoaʻili i kaʻeleu agena a me ka iodo. Ban, ua nui aʻe 'o cardiac conduction a me Episode o bradycardia me ka syncope. Mai i ka hoʻohana i ka lāʻau i hāpai keiki, a lactation. Lactation, i ka wā o ka lāʻau lapaʻau e hooki breastfeeding.

kekahi koi

E e pono kākoʻoʻia e ke kahuna lapaau e pono pākōlea hana lāʻau ' "Amiodarone". Na Ke Kumu no ka hoʻohana ia kekahi e hoʻohana papa ma hope o ka X-Ray study o ke akepaʻa, me nā maʻiʻaʻai, a o ka electrocardiogram. O ia ka mālamaʻana e halihaliia oia iwaho i loko o ka wā e hiki mai, ina ka hoʻomanawanui mau, e lawe i ka laau lapaau.

Ke oolea o adverse hanana pinepine hilinaʻi nui ma luna o ka mahele lāʻau, a hoʻohana i ka hoʻomanawanui. E ho'āʻo i ka hoʻohana 'ana i ka lāʻau' like infrequently i hiki, a ma ka palena haʻahaʻa mea. Pinepine ke kumu ole Kal ke kāpaeʻana "Amiodarone" lāʻau.

Na Ke Kumu no ka hoʻohana - hōʻike manaʻo e olelo aku nei ia, ma naʻe o kaʻaoʻao waiwai, ua hoola keia k oi ma mua o kekahi ola - mai nei i ka pharmacological hana o ka lāʻau ua mālama 'ia no kekahi mau pule ma hope o kona ke kāpaeʻana.

Papa pihaʻi me iodine, i ka poʻea pau i ka hoʻomāhuahua kiʻekiʻe o radioiodine i loko o ka thyroid gland. No laila, i ka hoʻomaka o ka pākōlea lapaʻau, i, a ma ka hopena e pono ai i mau e ikea no ka nui o ka thyroid hormones.

Ma pākōlea uao mea pono e pale aku hooloihi ae i lā waiū, ia mea,ʻaʻole e pono ke lawe i ka hamama lā. Ka lāʻau 'E e lawelawe me ka mālama nui i ka poʻeʻelemākule kanaka me ka mau anesthesia ai' ole ma ka papa o ka ka oxygen lapaau. Me ka mālama nui ia e hoʻohana i nā O Keaukaha o kaa a me na kanaka nona kaʻoihana ua pili me ka ua lehulehu.

Ma na hihia o ka overdose i ka mahina worsening o kaʻaoʻao waiwai, e like me ka pono me hypotension, arrhythmia. Kānāwai bradycardia ai ole o ka af conduction. An overabundance e alakai i ake dysfunction.

Ma keia hihia, ua waiho koke gastric lavage,? Aaeno? Ho'ā 'charcoal, Saline laxatives paipai pāʻoihana. Inā bradycardia injections o atropine, hoʻohana agonists o Hoʻokolohua-adrenergic receptors, hua mai la i auhele.

Pilina me nā lapaʻauʻia

Kaiapuni E e hoʻohana lāʻau 'ka poʻe me ka' ē aʻe ai ', o ka oi aku ina mea e, mai ka ia pae o antiarrhythmic. Ia mea,ʻaʻole e pono ke hui pu iho la ia me ka? Eaia "erythromycin", "pentamidine" a me "vincamine." Aia He He pilikia o polymorphic ventricular tachycardia ma ka hui pu ana, me ka "sultopride". Ua ua i? Aeiiaiaiaaiiʻai ana CCB a me ka Hoʻokolohua-blockers me "Amphotericin B" a me ka ai 'ana i ka laxative kanawai, diuretic. Me ka mālama hoʻohana i ka lapaʻauʻia i loko o ka hui pu ana me corticosteroids, antidepressants, "Astemizole", "terfenadine." Hiki no me ka nui loa ka hōʻoi 'i ka hopena o ka ai' like "Warfarin", "Phenytoin" "Tacrolimus" a me "Digoxin". Wā hoʻohana i ka huipūʻana me "cimetidine" 'aʻole hoʻi ia i ke kaʻina hana o ka pūnao i loko o ke kino.

Life a me ka pūnaewele hae

Ka medicament "Amiodarone", kona hana ua kuhikuhi ma ka hoʻopau o ka tachycardia, ventricular fibrillation, tachyarrhythmia a me atrial kolili ka ho'ēmiʻana, pili ia i hoʻomākaukau waeʻano "B" pae. Holopapa-ola o ka lāʻau, ua emi o na makahiki ekolu. Papa e waiho waho i loko o ka me, pouli, a mai ka loaa ole o na keiki.

i ke ano o ka "Amiodarone" lāʻau pono e malama ikaika lāʻau. Ka beauty e hoʻohana mea kākau mai i kekahi kauka. Ma keia hihia, pono e loa hoʻokoe 'ke naʻu.

Analogs medicament

Inā 'oe koke i i pono i ka lāʻau "Amiodarone" analogs hiki ke loaʻa i loko o kekahi hale kūʻai lāʻau lapaʻau. Iwaena o lakou e ai 'e like me: "Amiodarone Belupo" a me ka "Amiodarone Aldaron", "Angoron" a me ka "Atlans" a puku ia me ka lapaʻauʻia hiki "Kordaron" a me "Kordinil". Similar e "Amiodarone" i loko o kona waiwai ma luna o ka kanaka kino "Medakoron" a me ka "Palpitin". Ma kekahi mau hihia, i ka lāʻau ua UAIAaIN e "Sedakoronom" a me ka "Sandoz".

Mau ai 'kekahi māmala'ōlelo i loko o ka iaʻeleu waiwai a like i loko o kā lākou antiarrhythmic hopena o ka lapaau "Amiodarone". Analogues i pinepine hua mai la i ka lono, a he mau manawa hou aku pipiʻi.

e hoike

He nui nā mea maʻi i aku nei au i ka noaaeeecaoee o ko lākou mau manaʻo ma hope o ka lawe i ka oihana lapaau, "Amiodarone". Na Ke Kumu no ka hoʻohana - pinepine i koho lāʻau analogs ma muli o na ano kanaka o ka meaola - olelo hoopomaikai e normalize i ka naau ana, puʻe. I ka intermittent? Eaia ma ka liʻiliʻi nā māhele, ano laulā,ʻaʻohe pilikia, a me ka lāʻau a pau ka pono.

Ma hope o hooloihi ae i hoʻohana o ka lāʻau i loko o kekahi nā mea maʻi iʻikeʻia pokole o ka hanu, naau palpitations, nervousness a me ka kaumaha, naʻau i loko nā poʻohiwi, a mahuahua thyroid hōmona, he kāna hana o ka gastrointestinal'āpana, a ma kekahi mau hihia, nausea a me ka luaʻi.

Loa na kanaka hana ia i loko o ka iapaau ana o ka angina, a e hoailona oukou ia ia mea iʻoi aku ma mua o laweia mai counterparts. na kanaka kekahi e makau i ka lawe i ka lāʻau, no ka mea, i loko o ia, oia mea hiki ia i ka helu o Ka maʻi 'aʻai. Ua Ua manaoio aku la au e laweiaʻe ia i ka lāʻau ma lalo o ke ano e Hoʻoweliweli 'o ia kanaka ola wale nō, ma nā mea a pau nā wahi, i hiki, e nana no i kekahi koho. Eia hou, i ka papa hiki i ka hopena maikaʻi ma luna o ke kane reproductive hana, i mea hoi e e noʻonoʻo i kā lākou? Eaia.

Akā, no ka nui lāʻau "Amiodarone" ka mea, ua he panacea, mahalo no i ka maʻi i emi, akā, i ke kanaka koe e ola ana. 'Aʻole i ka mea i analogues makemake e like me ka hoʻokō. No laila, i loko o ka iapaau ana o ka naau maʻi, mai i uku ho'ēmi i ka lāʻau 'aku, o ka oi aku ina ke kauka ia kekahi mea.