"Plagril": aʻo no ka hoʻohana 'ana, maoli kauka. Uluwehi O analogues "Plagril"

Maʻi o ka mea'ōnaehana mānowai koko'ōnaehana i loko o kēia lāʻau paha i loko o ka wahi mua. I ka make ana o kēia mau maʻi i luna lilo loa. Aia nā pilikia ma keia wahi i hiki holoholo ai i kekahi kanaka, mai ka manawa mai o ka hanau ana. Eia naʻe, loaʻa nō ka poʻe i loko o i kekahi kanaka i ka iho 'ana i lawe nui "na makana". Kekahi mau maʻi - atherosclerosis. Inā keia pilikia e loli aiʻano nui arteries'ōlewa a me ka laholio Muscle-type. Ke ae pā o ka maʻi i loko o ia, ma muli o ka 'aʻe' ana o kumuʻiʻo a me ka lipid pūnao loaa i loko o nā arteries o ka naʻokoko hoʻokomo kālā a me kekahi constituents o lipoproteins. Pela i hana atherosclerotic plaques. Over manawa, i ka connective'aʻaʻa o ka moku pā i loko o kēia mau plaques hoʻonui, kūpono ma ka hou o ka lumen o ka artery a ka occlusion.

I mea e kōkua kēia mau hoʻomanawanui iki mai, ua ulu ka noiʻi i ka papa inoa o ka ai 'e hiki' ūlōlohi mai ana paha loa uhi i ka aggregation kaʻina (i huiʻia, ka ponaʻana) o platelets. Waiwai a me na uea 'i kapaia antiplatelet (antithrombotics). Kekahi i ka lāʻau o "Plagril".

'Ole a me ka haku mele' ana

Ka lāʻau 'Ua loaʻa ma ka papa kapa komo iā ia me ka manaʻoe kūkulu ka penaʻana a pink. Nā papa e poepoe, biconvex. Ma kekahiʻaoʻao crammed embossing "C 127". I ka papa kuhikuhiEʻeleu 'Oponopono o ka lāʻau - clopidogrel. Incidentally, i loko o ka lāʻau "Plagril" Inn (International Nonproprietary Name) mea'ālike i ka inoa o ke kumu nui ke keʻena - clopidogrel. Ka buke maʻiʻo no papa - 75 mg. Ma waho o ka papa kuhikuhiE eiiiiiaiou o ka medicament e excipients: microcrystalline kelulose, mannitol, croscarmellose paʻakai, colloidal silikone'okikene lua, makanekiuma stearate. Manufacturers paka i ka lāʻau ma ka blister he huihui 'ana o 10 apana.

Keʻano papa hana o ka lāʻau

I ka lāʻau o ka maopopo inhibitor (inhibit - inhibit, uhi i kekahi kaʻina) aggregation (hui) platelets. Ua loaʻa koronarorasshiryayuschee hana. Kaʻina deceleration platelet aggregation (ma kahi o 40%) hiki ke ike ma hope o 2 hola ma hope o 'ai, inu o ka lāʻau ma ka laʻau heluna o 400 mg. I mea e hoʻokō i kā mākou ka hoʻokōʻana (60% inhibition o aggregation) loa mai ka papa "Plagril", kuhikuhi no ka hana e like me ka mea e pono ai no ka Inc no 4-7 lā. Ka huina mahele lāʻau no ka lā e ia mai ka 50 a hiki i 100 mg. Ma keia hihia, antiplatelet kanawai, e mau no ka mea a pau ke ola kalapona o platelets (7 i he 10 lā). Loko o 5 mau lā ma hope o ka lāʻau 'withdrawal uku o ka platelet aggregation, a kahe ana ke koko manawa hoʻi i ka loiloi mua hana.

Excreted "Plagril" hakuʻala a me ka naʻau liʻiliʻi (50% a me ka 46% niioaaonoaaiii). deducing Wā - 120 hola ma hope hooponopono.

Ke kumu nui nā mea kūʻai mai o "Plagrila"

Aia i kūikawā pae o ka naau e hoomanawanui i ka poe i ike ia e pili i ka lapaau "Plagril". e koi Na Ke Kumu, e lawe i ka lāʻau no nā poʻe loaʻa mai atherosclerosis. Ka lapaʻauʻia ka mana me ke kāohi ana, e emi i ka pilikia o complications pili me ka thrombosis i loko o kanaka, ka poe i loaa i ka myocardial infarction a ischemic hahau ana. He pū oiaio no nā mea maʻi e loaa ana mai ka occlusion (ka mea hōʻemi o permeability)ʻike ākea arteries.

Ma tandem me acetylsalicylicʻakika (aspirin) i ke hoʻohana ' "Plagrila" i mea e pale aku thrombotic complications i loko o ka poʻe i hana eha iaʻi mai ka huʻi coronary maʻi pale. Kēia hiki nā kanaka me angina (lolelua ka palapala), me ka myocardial infarction me ka ho okumu nalu Q. 'oe ke hoʻohana i ka lāʻau i loko o nā mea maʻi i akaaka malu stenting. Ke ae pā o ka hana - mea hoʻonoho ma ka hoʻohuli ai i nā ipu stent (lahilahi kōkō metala şarkı), a mea a laila inflated kūikawā hoʻonui, hiki mahuahua i ka permeability o ka moku a me ka hoʻomaikaʻi koko i ka naau.

Laʻau heluna: ke noi 'ole

Medicine "Plagril" e hoomanawanui i hiki ke lawe hōʻike waha, nānā 'ole o kaʻai. Ma nā mea maʻi undergoing myocardial infarction, ischemic mapuna hoe a hoʻokumuʻike, e pili ana i ka patency o ka arteries mea hōʻemi, i ka mahele lāʻau o ka 75 mg ia i kekahi manawa, i ka lā. Au o ka lapaʻau Inc ma hope o Q-nalu myocardial infarction i hope mai i 35 mau lā. Ma ischemic hahauʻana, ke kaumaha ma muli o ka oolea o keʻano, hoolaia e ka ÷ 7 lā i eono mahina.

I ka hahau ana ma ka lolelua ka palapala, a me ka myocardial infarction me ke kahua o Q-nalu mea nō kāu he maʻamau regimen o ka papa, ua like penei: mua, hoʻokahi-manawa hoʻouka mahele lāʻau o ka 300 mg, i ukali ia e 75 mg no ka lā a me ka aspirin (75 a hiki i 325 mg no ka lā). No ka mea, i kaʻai ana o aspirin maoli i ka pilikia o ke kahe ana ke koko, ke i kā mākou hookahi mahele lāʻau e ole oi 100 mg. Lāʻau lapaʻau - mai ai i 1 makahiki.

? eaia "Plagril" antiplatelet Inc ua kekahi hōʻike no ka huʻi myocardial infarction. I hoakaka ia huaale e lawe i kekahi mahele lāʻau o 75 mg, i loko o ka hoʻokahi lā. ? Aeiiaiaiaaia e hoʻomaka lapaau me ka loiloi mua hoʻouka mahele lāʻau i loko o ka hui pu ana me ka acetylsalicylicʻakika. Paha i loko o laua lawe thrombolytics (paha e ole lawe).

Inā nā mea maʻi i kēlā 75 makahiki o ka makahiki kali, "Plagril" (like i ka clopidogrel hoi e maliuʻia) ua hoonohoia me ka loiloi mua hoʻouka mahele lāʻau. Ma hope iho o ka helehelena o ka hoʻohui pū iapaau ana o symptoms e e hoʻomaka 'ana i kakahiaka nui me hiki. Ka papa E mau ma ka liʻiliʻi 4 pule.

Hikiʻaoʻao waiwai o

I loko o ka papa o ka lapaau ana me ka hoomakaukau "Plagril" manual hoʻomaopopo 'o ia i keʻano o ka hikiʻaoʻao' ole mai o nā 'oihana likeʻole a me nā loko.

koko clotting'ōnaehana hiki pinepine pane i ka helehelena o gastrointestinal kahe ana ke koko. Emi pinepine e ulu hemorrhagic hahauʻana, kahe ana ke koko mai ka ihu, a, me ka mau, me ka hoomahuahua i ka kahe ana ke koko manawa. Ma pohihihi keia hoopii, e ikea hematomas, hematuria.

Kula Kaiapuni 'o ka hōʻike' ana mai o ka hemopoietic nenoaiu. O nā eosinophilia, neutropenia, thrombocytopenia. Ālai 'emi paha, e hoʻoikaika i granulocytopenia, hemahema hoi paha aplastic anaemia.

Ma ka hapa o ka Central a me kaʻike ākea ko mākou hopohopo'ōnaehana i e headache, pōniuniu, paresthesia, vertigo (lilo o ke kaulike, pu ma ke ano o ke kuapo ana o nä mea a puni ke kino, a me ka hope versa - i ke kino o ke kuapo), hallucinations, hilahila. Muli o kona kulana pohihihi, akā, na hihia o adverse hanana ana me ka mea'ōnaehana mānowai koko'ōnaehana, ma ka hua'ōlelo o ua hoʻemi ke koko, vasculitis ulu. Bronchospasm a interstitial pneumonitis - keia i e ka naoh o ka naehana'ōnaehana e loaa i ka waiʻona.

Loa pinepine ma ka lapaʻauʻia "Plagril" (hōʻike manaʻo o ka lapaau a me nā mea maʻi eʻae i kēia mea) reacts digestive kahua. Ke naoh o ke kino ua hoikeia i loko o ka ulu ana o ka diarrhea, dyspepsia, abdominalʻeha. Emi, he pono ole hiki reactions e like me nausea, ka luaʻi, constipation, huʻi gastritis a me ka gastric a me duodenal ulcers, flatulence. Pohihihi keia akā, e hiki hanana o ka maʻi e like me colitis, pancreatitis, stomatitis, hepatitis, hoololi ae hoao, e ulu ai o ka huʻi akepaʻa ole.

Osteo-muscular'ōnaehana ke hai iho arthritis, myalgia. ʻOiai ka mea, ka hana i kākaʻikahi. Glomerulonephritis i ka hopena, mai ka naoh o ka urinary nenoaiu. Dermatologists paipai i kekahi e hiki no i ka "Plagrila" ka ohane, bullous poʻe noʻonoʻoʻole, erythematous poʻe noʻonoʻoʻole, lichen planus, eczema. Paha i ka hooulu ana o allergic reactions i loko o ka palapala o ka angioedema, anaphylaxis, lāʻau lapaʻau maʻi. No ka mea, he pono oleʻaoʻao waiwai i ke kaulana wela, ke kiekie lāʻau lapaʻau creatinine.

Ka hoʻohana o "Plagrila": He aha e nānā no ka

Inā no kekahi mau kulana home 'ole mea undesirable antiplatelet keiki, a ua manao eʻoki kino, oe e ana i ka iapaau ana me "Plagril". Na Ke Kumu no ka hoʻohana ia kekahi e hana ai i ka liʻiliʻi 7 lā ma mua o keʻoki kino. Ma hope iho o ka abolition o ka lāʻau, e hooki aku i ala koke kahe ana ke koko, e pono hou manawa. Hoʻomanawanui iki mai E e ao e pili ana i ka mea a ka manao e hai aku i ke kauka e pili ana i na hana kahe ana ke koko. Ma ka pono o ke hoʻomanawanui, e hai aku i ke kauka e pili ana i ka iapaau ana o "Plagrilom" i loko o ia mau hihia a pau, ina e e kekahiʻoki kino, a ua ia ke hoʻomanawanui i kekahi hou lāʻau.

Ma ka papa o ka 'inikua Inc mea nui e malama i ke kāohi o ka'ōnaehana kiko'î o homeostasis (platelet helu, e ho'āʻo ai o ooieoeiiaeuiiai haʻawina, APTT). Ka iaea ooieoeiiaeuiiai ha awina o ke ake, a ina e mau ua hoʻonānā a loiloi 'like loa deviations i loko o kona hana ke hoʻonui i ka pilikia o ka hemorrhagic diathesis.

Medicaments, nona ka papa kuhikuhiEʻeleu 'Oponopono mea clopidogrel ( "Plagril" analogs), ua i pono no ka poe i waiho wale aku no i ka huʻi myocardial infarction, ma ka liʻiliʻi loa i loko o ka mua mau pule ma hope o hookahi. Lapaʻau 'Oihana e i waiho aku "Plagrilom" Inc ina ka hoʻomanawanui i lolelua ka angina, me ka ischemic hahau ana i loko o coronary holo alaʻokoʻaʻoki kino.

Me ka kekahi dala o ka mālama nui e koi 'ia e lawe i ka lāʻau no nā kanaka me ke kino kīnā i loko o ka functioning o nā puʻupaʻa.

E LIKE-? Eaia "Plagrila"?

"Plagril" (papa) aʻo ua papa nā mea maʻi me ka hypersensitivity paha intolerance i ke kanaka ka papa, a kākoʻo eiiiiiaiou o ka medicament. Mai lawe i ka lāʻau ma kekahi maʻi predisposing e kahe ana ke koko (gastric a me duodenal ulcers, hyperfibrinolysis, akemāmā Ka maʻi 'aʻai, tuberculosis, etc.). A ikaika kumu no ka mea ole-hoʻohana "Plagrila" i huʻi hepatic e hemahema, hemorrhagic maʻi pale. Ma waho aʻeo ia ka mea ma luna, ua contraindicated lawe ka lapaʻauʻia no ka hapai keiki o na wahine a me ka poe makuwahine. Not e koi 'ia i ka lāʻau a hiki i na keiki ma lalo o makahiki 18 o ka makahiki.

hoomakaukau analogues

Ma ka mea lāʻau lapaʻau market i kēia lā, i ka pae ana ai 'antiplatelet Luna ( "Plagril" synonyms kona maʻiʻo o ka papa kuhikuhi hana eiiiiiaiou) loaʻa lawa kaiāulu. More ma mua o 3 kakini ai '- antiplatelet Luna i ka ia hana' Oponopono (clopidogrel) a ma ka ia laʻau heluna (75 mg). Kaawale mai Lūkini Manufacturers paka antiplatelet Indian mea lāʻau lapaʻau poʻe, hana Hungary, kaʻIseraʻela, Malta, France.

"Dr. Reddies keʻena hoʻokolohua" "Plagril" iho produces he Indian poe. By analogy, ua hiki ke loaʻa i ka Palani "Plavix" Kelemānia "Clopidogrel ratiopharm," Hunakalia "Clopidogrel-Richter,"ʻIseraʻela "Clopidogrel Teva," Malkī "Liporel" Teselonike i "Listab 75". "Zilt" hiki ke kaʻawale mai ka loa kaulana loa, a kaiāulu i loko o koi Lūkini konohiki.

"Zilt" - Russian "Plagril"

I ka papa kuhikuhiEʻeleu waiwai o ka la hoomalolo "Zilt" ( "Plagril" i loko o ia mea, i loa e ku i) ka clopidogrel. Ka lapaʻauʻia no a hiki i ka pae ana o antiplatelet konohiki. Ka loiloi mua mahele lāʻau (no ka "Zilt" - 400 mg) ma hope o 2 hola ma hope o ka hoʻoponopono 'aʻole hoʻi platelet aggregation. E like me "Plagril", "Zilt", aka no ka loaa ana 50-100 mg no ka lā, e hoʻolako i ka i kā mākou pākōlea kanawai ma hope 4-7 lā.

Medicament metabolized ma ke akepaʻa. I ka haku mele 'ana o ke koko o ka hana metabolites ua' akomi i. Kahi o 50% "Zilta" excreted ma nā puʻupaʻa, i ka i koe, 46% i loko o 5 mau lā ma hope o loaa e e haalele iho ma ka liʻiliʻi.

Nāʻikepili no ka hoʻohana ana i ka "Zilta" i ka ia me ka "Plagrila": Kāohiʻana o ka thrombus ho okumu i loko o nā mea maʻi undergoing myocardial infarction, ischemicʻai paha e loaa ana, mai kāna hana artery patency.

consumer manao

Like kekahi lāʻau, ka "Plagrila" i nā maikaʻi auhau o nā mea kūʻai mai, nā maikaʻi a me ka io nāʻana. Aia nō nā mea maʻi i loko o ka mea a ka lāʻau i ua hoonohoia no ka lapaau ana o angina , a hoike aku ia ia iho i ka mea pono ka lāʻau. A me kona hoʻohana o ka ho'āhewa wale i wahi paha ma nā mea a pau, a lilo nunui emi ka mea. Together me nā mea kūʻai mai i loko o ka loiloi 'ana o ka laau "Plagril" pane mai o na kahuna lapaau.

Eia naʻe, e hiki hālāwai a me nā loina e pili ana i kaʻaoʻao ona, kena ae la ma ka hoʻohana 'ia o ka lapaʻauʻia. Kekahi kanaka i kākau e pili ana i keʻano o ka paopao koke mai oia, 'ē aʻe maopopo hoikeia anaemia. Ka mea, he hoʻomanawanui iki mai, a ia la aku Episode o loa headaches, a me ka loa okoaʻaoʻao kāna hana i loko o ka digestive nenoaiu. Pohihihi keia, akā, hiki ke lohe i ka holomua ma ke kaʻina hana o ka loaa ana "Plagrila" gastric ulcer a duodenal ulcer.

Ma mau, ka mea e e olelo mai la ia i ka lāʻau "Plagril 'kauoha no ka hoʻohana ua hoʻonoho like me ka nui lawa lāʻau mea i hana maʻalahi me nā lāʻau. Ua he 'ano nui papa inoa o nā contraindications, hiki i kekahi wahi lihi iki o kaʻaoʻao loa, mai keʻano o nā nenoai a me nā loko. Kipi ana ke hoʻoulu lawa ka hopena maikaʻi (a me kekahi manawa irreversible) hopena no ka ola o ka hoʻomanawanui.

Ka hopena mai a pau na luna o ka hoʻoponopono-akaka. "Plagril" no ka iapaau ana ala e e hoonoho ma ka hele kauka. A me ka pono koho o ka iapaau ana me keia k - i loko o ka haukapila, a ma lalo o ka hooponopono ana o alakai mākaukau. Wale i keia hihia, ua hiki ke manaolana no ka maikaʻi loa o ka lāʻau a me ka palena haʻahaʻa pilikia o kaʻaoʻao loa.