Thyroid goiter

Follicles a epithelial keena - kēia mau mea i ka hoʻokumu paʻa mall a me ka ooieoeiiaeuiuo huahelu o ka thyroid gland. I ka papa kuhikuhiE ke keʻena o ke kumuʻiʻo colloid - thyroglobulin. Ka inoa hui pili i ka glycoproteins. Ke biosynthesis o thyroid hormones a me kā lākou kaawale ana i loko o ke koko ua hoi malalo o ko thyrotropin anterior pituitary (TSH), kona hoʻololi kemikala ua hauma¯na a inhibited ma somatostatin tireoliberinom pituitary. A hiki i ka lehulehu o ka iodine i loko o ke koko thyroid hōmona pituitary kuleana pili i ua hoemi, a me ka shortage - listen. Hoonuiia lehulehu o TSH ka hoʻonāukiukiʻana,ʻaʻole wale nō keʻano o ka hanaʻana amplification iodinated hōmona biosynthesis, akā, i eiei? A nodular hyperplasia o na nā'aʻaʻa o ka thyroid gland.

ʻike, o ka thyroid mai ua i ka hoʻohana 'ana lapaʻau, pathological a me ka biochemical a me ka morphological' ana i kūpono. Ma muli o ka 'ikepili i ka mea kēia mau maʻi: endemic goiter, hypothyroidism, lua kupapaʻu' maʻi, sporadic goiter, umauma hikoko.

Lua kupapaʻu 'maʻi ua wehewehe aku ma ka hypersecretion o thyroid hormones a me eiei? Hypertrophy o ka thyroid gland. Kēia pathology ua noʻonoʻo i ka genetically mediated autoimmune maʻi i mea hereditary. Hoonaukiuki i ke kūpono 'ana o ke goiter infectious loohia (maʻi palū, parainfluenza, inflyuensa), pharyngitis, tonsillitis, encephalitis, stress, lōʻihi-makahiki hoʻohana' ana o ka iodine hoomakaukau ana. Ano no ka maʻi mea eiei? (Kekahi manawa ole) hoonui thyroid cachexia.

Hashimoto pili i ka autoimmune maʻi wehewehe aku ma lesions o ka thyroid gland, hōmona hoʻololi kemikala kāna hana. Kēia palapala tireroidita wehewehe aku ma ua hoʻemi hoʻololi kemikala o hormones (triiodothyronine, thyroxine) a me ka thyroid hypertrophy. Kēia pathology Ua oi paha ia e kakau i na wahine ma mua i loko o nā kānaka.

Endemic goiter o ka thyroid gland - he maʻi maʻi wehewehe aku ma ka ulu i loko o ka endocrine glands, kue o kona oihana, pūnao, kāna hana o ka ko mākou hopohopo a me ka mea'ōnaehana mānowai koko nenoai. Deficiency o ka iodine synergists (kiniki, cobalt, keleawe, manganese) a me ka liki ole hakaka (kalipuna, strontium, kēpau, bromo, makanekiuma, hao, fluorine) he hoʻonui i ke kūpono 'ana o ka maʻi.

Ma waho iodine deficiency goitre ulu triggered ma kaʻaiʻana nui ka nui o nā huahana me antithyroid Luna (goitrogens). Ma keia hihia, ka mea, ua ulu nontoxic goiter o ka thyroid gland. Hooloihi ae i iodine deficiency hoʻololi kemikala o T3 a me T4 ua hoemiia. No ka mea, no kēia mau biochemical loli i loko o ke kino uku 'maomeka nā, ma ka nui, māhuahua secretion o TSH ulu prostate hyperplasia (parenchymal goiter thyroid). Eia hou, i ka hoʻokāʻoi 'adsorption o iodine ma ka thyroid gland (4-8 manawa) maoli he T3 hōmona hoʻololi kemikala, liluwelo hana i mea 5-10 manawa oi aku ma mua ia o ka thyroxine. I ka wā e hiki mai uku 'maomeka mai aole i hiki maopopo hoʻopau i ka palapala ole o ka lōʻihi-makahiki iodine deficiency. Ke endocrine gland atrophied glandular'aʻaʻa, e hana cysts, adenoma, oiai ulu connective'aʻaʻa i ka ulu thymus hypertrophy o ka thyroid gland. A hiki i kaʻike, o "thyroid goiter" ko lakou kupikipikio lipid, carbohydrate, kumuʻiʻo, a me ka wikamina a me ka mea pōhaku pūnao.