Thyroid hormones: ke kumu, ke kumukuai o ka pathology

Ke kanaka kino - he manaʻo aukahi'ōnaehana i loko i nā mea a pau keʻano o ka hanaʻana i hooponopono ia e kekahi i kekahi. Me kēlā hui, i loko o kona haku mele 'ana ka poʻea pau e malama i ka pono o ka hana.

A me ka lolo o kekahi o ka mea nui hoʻokonukonu maomeka - na kanaka endocrine nenoaiu. Ua hāpai mai kona hana ma ka endocrine glands, a pee hormones me kekahi hiʻona a me kekahi tropism no ka pale keena. Pela, ke thyroid gland Radio nui i kūlana i loko o ke kino o ka ulu a me ka loli ai a pau ke ano o ka launa like. Ua hōʻike ana i nā thyroid hormones, a he hoʻonui ai i ke kino ai, noʻonoʻo kūpono 'ana i loko o na keiki, i pūnao a me ka ikehu i loko o nā mākua. I hoʻi, kā lākou? Iecaianoaaiiie ua hooponopono ia e na ko mākou hopohopo'ōnaehana, o bioactive waiwai pituitary a me ka hypothalamic ka hoʻokuʻu 'kumumea. Penei, thyroid hormones mea mau ma ka kekahi kiʻekiʻe i loko o ke koko, a hoonui i ke kino me ka kūikawā e pono ai, i ko lakou kinikini i hiki i ka hōʻike i ka nele o ka thyroid kuleana pili i a me ka iodine.

hormones

Glandula thyroidea (thyroid) ua pili i ka trachea, a he o ka akau a me ka haʻalele lobes e pili ana ma ka isthmus. Direct hoʻololi kemikala o ka thyroid hormones ua hana i loko o kona follicles piha me ka colloid loko, a ua nānā 'ana i kumuʻiʻo - thyroglobulin. Me ka hou iodination o ka tyrosine residues i loko o kona 'ole, a mahope summation o na hui loaa a me ka hana triiodothyronine a me ka tetraiodothyronine (T3 a me ka T4). E möakäka hou tireiodnye hormones loko mai thyroglobulin lātoma a pipili, a kuu i loko o ke koko i loko o noa palapala. Ka mea, i okoa nā hoʻohui like, a me ka lauwili ma potency (T3 kū me ka nui loa ma lalo nā māhele, akā, kona potency mea nuiʻoi aku ma mua ia o ka T4). Naʻe, i ka hopena o hormones ma ke kino i ka mea hookahi: hoʻokāʻoi aʻe ana i kona kaikea a me ka carbohydrate pūnao (mahuahua monakō koko pae) kāhea gluconeogenesis, ake glycogen inhibit ho okumu a me ka hōʻoi ' kumuʻiʻo hoʻololi kemikala (i loko o ka excessive na dala, conversely, ka hōʻoi' disintegration o ka hope).

Ua Ua hoikeia aku ai e na mea i ka mea, malama i ke koko, a me ka naau i kela a me kino wela, hōʻeleu i ka noʻonoʻo a me ka 'ehaʻeha o keʻano o ka hanaʻana. Ma ka embryonic wā thyroid hormones i kuleana no ka differentiation o nā'aʻaʻa ma ke kino. I ka noho 'ana kamaliʻi, he hoʻonui i ka ulu a me ka noʻonoʻo' ana o ke keiki. Eia hou, e hōʻoi 'erythropoiesis, haahaa omo reabsorption o ka wai.

maʻi

Ma kekahi maʻi, thyroid ua hoemiia hōmona secretion (hypothyroidism). Ma keia hihia, ka mea pono e UAIAaIN ma ka lapaʻauʻia. I hiki compensate no ka nele o ka maʻiʻo hehee wale ia BAKC thyroid hormones? Ai 'hoʻohana' ia i loko o keia hihia - ka "Levothyroxine" (T4), "Liotironin" (T3) a me keʻano o ka iodine-i loaʻa ai '. E like me ke keakea, a me ka loa thyroid hormones alakai i metabolic kāna hana i loko o ke kino i ka mea clinically hoike kue o ka homeostasis a me ka psychomotor hope. Ke degere o ka poho hilinaʻi nui ma luna o ka hoʻomanawanui i ka makahiki (cretinism wale nō i loko o nā keiki), i ka nui o ka shortage a oi o hormones (hyperthyroidism 1, 2, 3 degere). Ma hope ka mea, he pokole o ka hanu, palpitations, mahuahua ke koko, kāna hana no nāʻano launa. Me ka nele o, ma ka mea ku ole, ua hoʻemi pūnao, i ke ahonui i sluggish, indifferent.