ʻakika phosphatase i loko o ke koko: manao paa, ho omńkalakala a me ka uku

ʻakika phosphatase - he'ūhū e hōʻeleu i ke decomposition o nā lātoma i loko o ke kino. Hoʻoholo 'o kona pae i loko o ke koko mea nui no ka diagnosing ke ola kulana. He nui na ano o kaʻakika phosphatases, a kaʻana like i ka functionally'ālike, akā, OAOOUIEeE nunui mai kekahi i kekahi ma ka pili ana i ke kino o nā'aʻaʻa, chromosomal kumu, haku mele 'ana.

Ka lōʻihi o ke

LIKE'ūhū ma ʻakika hana kūpono, nolaila, i ka inoa. ʻakika phosphatase ua loaʻa i loko o kekahi mau nā'aʻaʻa a me aeee i ke kai piha ma nā lysosomes, a ma o aku. Ua nui loa ka helu hoʻoholo i loko o ke prostate gland, e like me ka keena o ka hope o nā loko:

• ake;
• spleen;
• iwi ka lolo;
• koko aeee (erythrocytes, platelets, macrophages).

Ma ke olakino meaola i ka ha awina oʻakika phosphatase meaʻano haʻahaʻa. Na elele o ke kane hapalua kona kiʻekiʻe ninoieo o ka prostatic phosphatase, a me ka mea a ua luku ma ke ake a me ke koko keena. hana loa luku e ke ake a me ka erythrocytes, platelets nā nā'ūhū o ka wahine kino.

Lysosomalʻakika phosphatase

Ia ke aupuni 'o ka hapanui keena. Kona shortcoming mea he autosomal recessive maʻi, a ua manaoia e ia i ka hopena o pathological metabolic keʻano o ka hanaʻana. Symptomatology o ka maʻi hoike mai ai ia ia iho e like me penei:

• intermittent nausea a me ka luaʻi;
• nawaliwali, kahe ana o ka hoʻokōʻana;
• hakumakuma ke koko;
• ma ka noho 'ana kamaliʻi - opisthotonus (ke kāʻili' ana e hoʻomaka ai e pio ana o ka piʻo hope, e hoomanawanui i hilinaʻi ma luna o ka ili o ka wahi moe wale ai, a me na wawae);
• kahe ana ke koko.

Inā ka'ūhū pae Ua lawa wale nō i loko o keʻokeʻo koko keena, e hoomanawanui i pinepine e ae exacerbations o ka maʻi nā mea palahēhē.

Prostaticʻakika phosphatase

Ua Ua manaoia i ka peni mäka o ka maʻi 'aʻai keʻano o ka hanaʻana prostate. Kēiaʻano o ka'ūhū ua nānā ', a me ka hua peni mäka loli ma ka hookolokolo (kūlanakauhale). ʻakika phosphatase ua ho'ālaʻia, a he mau lā ma hope oʻoki kino ma luna o ka prostate gland a biopsy kāʻei kua.

Kaʻoi loa pH anakahi no ka pono functioning o ka'ūhū - 4,6. Activity mea akaka wale nō ma hope o ke kanaka i kīnā puberty.

Currently, i maopopo ai ka nui o prostatic phosphatase like me ka peni mäka o ka maʻi 'aʻai emi ana o loko o ke kāʻei kua o ka mahuahua ukupanee ma ka prostate-kekahi antigen, i mea hiki ke hoʻokūpaʻa i ke alo o ka maʻi ma kahua o ka hoʻonaʻauao mua o? Acaeoey. Aka hoi, nā hoailona o prostaticʻakika phosphatase mea nui i loko o ka luaÿi ÿana o ka recurrence o ka maʻi 'aʻai kaʻina hana ma hope oʻoki kino no ka'ano'ē prostate hoopau.

Ka Ikepili e hooholo i ka laulā o ka iapaau ana o benign prostatic hyperplasia a me nā prostatic pathologies.

eritrotsitarnaja phosphatase

He He polymorphic'ūhū i mea ole wale i loko o kaʻulaʻula keena koko akā, i nā keena o ke kino. ʻO kaʻoi loa pH no kona hana loli aʻe mai ka 5.2 hiki i 6,2.

ʻakika phosphatase koko hiki ke nānā 'ia möakäka hou paternity. Kekahi ano o ka'ūhū i pili me ka mea ma lalo nei:

• aaiaoe predisposition i hemolytic anaemia;
• pathology, a ua wehewehe aku ma ka hooulu ana o hemolytic anaemia i loko o ke kāʻei kuaʻai legumes;
• anaemia ma o ka hoʻohanaʻana i kekahi ai 'ole ulu ka maʻiʻaʻai ana i mea hoʻomaʻi a me ka mea koʻohune kumu.

Aia mau ano o ka erythrocyteʻakika phosphatase 'ana e pili pū ana i ka' aʻe 'ia ana i loko o kamaliʻi.

Macrophageʻano o kaʻakika phosphatase

Ke'ūhū mea nui i loko o kaʻike, o Gaucher maʻi. Kēia mea he ili maʻi i hoike mai ai ia hoʻomāhuahua i loko o ke akepaa, spleen, hakuʻala, lolo, akemāmā glucocerebroside (ke aloha waiwai, mai ka pae o ka momona). I ka maʻi ua pu ma ka nui mahuahua ma ka nui o na luna-i oleloia kino, heʻoi emi ma ka helu o nā mea a pau i ke koko keena, ke kāʻili 'ana, spastic kāʻili' ana, noʻonoʻo retardation.

ua Macrophageʻakika phosphatase i noʻonoʻo i ka hana i ho'ākāka 'peni mäka no ka huluhulu, ke kelepona hele leukemia. Kēia maʻi ua pu ma ka? Iecaianoaaiiie o ka nui dala o ka'ūhū, a me ka nānā 'ana ma ke koko.

phosphatase osteoclasts

Kapa osteoclasts iwi keena kuleana no kona luku. Kēia ka anu u He nui ka noonoo o ka iwi ka ulu a me ka remodeling pa alima. High mämä holo iwi poho accompanies ke kēia mau maʻi:

• Paget ka maʻi (pathological hoʻololi kemikala maʻamau iwi ho okumu a me kona oihana mua);
• hypercalcemia o malignancy;
• hyperactivity o ka thyroid a me ka parathyroid glands ;
• postmenopause ma ka hui pu ana, me ka osteoporosis.

Hopena - pinepine fractures a e holumua ai thinning o ka iwi kanu'ōiwi. Hoʻoholo 'ana oʻakika phosphatase osteoclasts hōʻike ke kiekie pae o nā'ūhū ma ke kāʻei kua o ka luna pathologies.

Hoomakaukau ana a me ka mālama nei lapaʻau '

Laupaʻi nā hoailona e hooponoponoia ia mea, ma ka keʻena hoʻokolohua ana. Ka Ikepili E e lawe mai ma hope o 2 lā, mai ka manawa mai o nā PalekanaEND_LINK kaʻina hana. Inā 'oe makemake e Loiloi i ka kiʻekiʻe o prostaticʻakika phosphatase, keia e e hana ole mamua aku ma mua o 48 hola ma hope o ka biopsy, palpation o ka prostate, bladder catheterization. I ka mea e ku pono hihia, nā hualoaʻa i e wahahee 'oluʻolu.

Pa mea no ka noiʻi lawe mai ma luna o ka nele'ōpū. Oe e inu wale i ka wai, inu kī, kope, Piʻihonua, a me nā mea inu ua pāpā. Iloko o ka lā, e pono e haawi aku i kanakaʻona mau nā mea inu, momoma, paka mau kīʻaha, 1 hora mamua i Ka Ikepili - mai e uwahi ana. Ka hope hapalua hola ma mua o kaʻai ana o ka mea pono e mālama 'ia ma ka piha' ehaʻeha o ka maluhia.

No ka meaʻike, o venous koko ua hoʻohana 'ia, o kona lāʻau lapaʻau ae ho'āʻo ana hemolysis. i ike ia ka anamanaʻo hualoaʻa i ka ia la ae, ma hope o ka mahele.

Ka hana hoʻohana

E möakäka hou i ka nui o ka huinaʻakika phosphatase hoʻohana immunochemical i kūpono me ka chemiluminescent ka loaʻaʻana. E hoʻohana i kūikawā substrates e pāʻani aku me kekahi mau nā'ūhū. Kēia nenoai Hoʻohana i luminol nā mea loaʻa peroxidase ma ka hui pu ana, me ka hydrogen peroxide pāʻoihana. Keia kanawai ua hou initiator (e laʻa me, N-yodofenol) hiki ke hoʻoulu i ka luminescence o ka pāʻoihana i mau tausani manawa.

Aia nō 'ē nenoai i hana kona'ākilikai phosphatase a me AMPPD kūpapakū, e ka PalekanaEND_LINK iaoia e oi ikepili koʻikoʻi. Pono o ka papa hana e, e noiʻi i ke kumupaʻa o reagents i hoʻohana,ʻaʻohe radiological kamepiula. Hoʻokau 'ia me ka nānā i ka ka manaʻo pohihihi o ka PalekanaEND_LINK kaʻina.

kūmau

Huinaʻakika phosphatase assays i hōʻike U / L. Kona allowable kiko'î oko ma luna o kona mau makahiki a me ka ka wahine.

Normal prostaticʻakika phosphatase nā hoailona - emi o 2.1 ng / ml. All huahelu ma luna hōʻike i ka maikaʻi hopena o kaʻike,.

A hiki i ka nui o ka'ūhū mahuahua?

Ka loa nui ana no i laupaʻi ana ma luna maʻamau:

• thrombocytopenia - he hoemi helu o ke koko keena kuleana no kona clotting;
• thromboembolism - blockage o ka lumen o ka papa kuhikuhiE artery thrombus, kaʻawale mai o ka moku pa, a me embolus, ka poe e noho ana ma ke koko;
• Hemolytic maʻi - he maʻi pu ma ka papakaukau loa ia'na o kaʻulaʻula koko keena, e wehe i nui dala o bilirubin i loko o ke koko;
• e holumua ai Paget ka maʻi - iwi pathology nakeke ma a ka imbalance ma waena o ka iwi ho okumu a me ka make ana o eiiiiiaiou i loko o ka lokomaikai o ka mea hope;
• myeloma - malignantʻeho kaʻina ke ano maoli, a ua hele ma ka B-lymphocytes, kuleana no ka hoʻololi kemikala o aiiay keena;
• Niemann-e koho i maʻi - hereditary pathology wehewehe aku e hoʻopōʻino momona pūnao a me ka hoʻomāhuahua o lipids i loko o ka nui nā loko (akepaa, spleen, akemāmā, naau, hakuʻala);
• i kekahi mau lā ma hope oʻoki kino ma luna o ka prostate gland a me kona'aʻaʻa biopsy.

ʻakika,'ākilikai phosphatase - he pūʻulu o nā'ūhū kuleana no ka nui keʻano o ka hanaʻana i loko o ke kino. He me kā lākou kōkua originate nui moekahi 'reactions. Hoomaopopo ana i ka nui o nā'ūhū e leie aku manawa, e kaha i ka loaʻa nui o ka pathology, a alakai aku ia i kākoʻo i ka iaea o hou kiʻekiʻe ma Hawaiʻi nei.