Avidity - mea 'aʻole ia ke ano o? Avidity IgG nā mea'aʻaʻa i Cytomegalovirus: nā hiʻona a me decrypting

Ano, oi aku a mau loa aku, ia mea nui ke kakahiaka detection a me ka prevention o infectious ka maʻi. Kēia pono kiʻekiʻe-ka pono a me ka kokololio PalekanaEND_LINK 'ana i kūpono. Mea maʻa mau? Aaieou hoʻohana serological epekema ka 'ike i ka oolea o ke kaʻina hana, a me ka mea E neʻe i mea hoʻomaʻi, mea koʻohune a me ka fungal maʻi. Akā, i kēia mau ho'āʻo ma mea ole ikepili koʻikoʻi lawa e maopopo ma waena o iniiaiie maʻiʻaʻai, reinfection a me ka relapse. Nolaila, kēia kānakaʻepekema i manaoia i ka papa hana no ka hoomaopopo ana i ka avidity o IgG-nā mea'aʻaʻa.

Avidity: heaha ia ano?

Hoomaopopo i ka manaÿo o mākou a me ka avidity. ʻo Solomona - he thermodynamic ano quantitatively hōʻike no ka ikaika o ka AaOIeIOUIeXAOAaIN o ka lāʻau lapaʻau kino, a me ka antigen o ka ia. I huli ai oe, o ka avidity e hoʻoholo i ka mea paʻa ikaika ma waena o ka antigen a me ka lāʻau lapaʻau kino. Këia mau manaÿo i pololei e pili ana i kekahi i kekahi. Ka hou antigen koena ai a eia i, ka ikaika o ka pilina. Hoomaopopo haʻahaʻa a me ka kiʻekiʻe avidity.

A 'o ia hoʻi kiʻekiʻe avidity? E ka noiʻi ana. I ka antigens komo i ke kino no ka manawa mua, ka mea hoʻoulu na keena B e paka immunoglobulins. Mua ia IgM, akā, a laila ka mea i UAIAaIN e IgG. Ma hope o ka papa mua o ka Solomona, a me keia wahi aku avidity, haʻahaʻa, like wale nō me ka kino i ka mea e malu ai maomeka e ke hakuloli i ka hou pathogen. Ma hope o nā hebedomaʻehiku, IgG «oʻo», ua nui kekahi, a no laila, ke kiʻekiʻe avidity. Ano, ma ka hihia o ka hou-maʻiʻaʻai, ka'ōnaehana paleʻea nenoaia e e makaukau e pane koke aku i ka olelo hooweliweli.

avidity Index

Level avidity inversely kalele iho ma luna o ka antigen mahele lāʻau, a me nā 'ano a me ka nui o ka mutations i loko o kanaka keena. Ka uuku o ka loiloi mua mahele lāʻau, ka mea maluna o ka Solomona, a me ka hope versa.

A laila, pathophysiology a me ka immunology eʻalo i ka kŰia o ka emi i hoʻonele me ka elemakule. Makou i manao ai, a ho oholo i kekahi mau hiʻohiʻona, i kapaʻia avidity inideka. He aha ke ano o ia aha avidity inideka? Kēia huahelu hōʻike i ka hoahanau ha awina o ka immunoglobulin, e hoopaa i antigen. Ke 'inideka ma ka laulā ma waena o 15 a me ka 50 pakeneka, IeOOAOeAAYAaE iniiaiie maʻiʻaʻai, ina o ka waiwai aku i 50 hapa haneri, alaila, i ka hoʻomanawanui i mua, waiho wale mai o ka maʻi.

rubella

Ke rubella mea hoʻomaʻi mai he loa hopena maikaʻi 'ole ma o ka fetus, no laila ia mea nui, e ike ai i ko ka expectant makuahine ua maʻi i ka maʻi, a ma mua hāpai keiki e e vaccinated. No ka PalekanaEND_LINK ana serological e ho'āʻo ai no mākou nā mea'aʻaʻa i na antigens. Inā immunoglobulins kokoke loa ma muli o ia ka mea hoʻomaʻi (particles), no laila, kiʻekiʻe avidity nā mea'aʻaʻa. Kēia e hōʻike kekahi i kekahi maʻiʻaʻai, a me ka maikai e hoʻonele ma hope vaccination.

I kekahi manawa, ukuia a hiki i ka stimulation o lymphocyte clones o ka rubella mea hoʻomaʻi ua 'akomi i wahahee maikaʻi naoh no immunoglobulin M. Eia kekahi, e like me ka hopena hiki ke ike ma ia mau nā mea maʻi i loko i ke kiekie koko rheumatoid ololi. Wale nō ka mea, he alo aku o nā mea'aʻaʻa mea i haʻahaʻa avidity. He aha aʻole ia ke ano o? Ua hiki ke noʻonoʻo i maopopo o ka iniiaiie maʻiʻaʻai me rubella mea hoʻomaʻi. Ma obstetrics mea he pololei PAaIEN no abortion.

toxoplasmosis

E like me ka rula, i kēia maʻiʻaʻai mea i hūnāʻia, a me ka hoike ana o ka lapaʻau symptoms me ka lilo ana pathology (e like, e like me pehu lymph aka wahi) mai ka haʻahaʻa PalekanaEND_LINK waiwai, i ka wa e pono e loaʻa mai pehea la ka loihi o ke kanaka mea maʻi. Hoʻoholo 'ana o IgG avidity nā mea'aʻaʻa mea nui kekahi a me ka' ikepili koʻikoʻi iaoia no kaʻike, a huʻi iniiaiie toxoplasmosis, i mea pakahi aku la ia nui ka wā ina hookolokolo hapai wāhine, e hoʻopau i ka Loaʻaʻia kamepiula o congenital toxoplasmosis i loko o nā keiki.

A nei, ka mea wale nō i loaʻa serologic mea o loko, e hooholo i ka oolea o ke kaʻina ua, e kuhikuhi i ke immunoglobulin papa M, a mahuahua ma ka titer o IgG. Inā i loko o ka hebedoma i ka nui o ka immunoglobulin G , a mahuahua nui eha manawa a oi, ia meaʻauhau'ēʻaʻe hoike o ka maʻi Holomua.

E like me ka serological ho'āʻo ma ke kauka mea hiki ole ke hooholo pono ia i kekahi kanaka e iho mailoko o, like immunoglobulin M a me G e hoomau ana no ka manawa lōʻihi i loko o ke koko. No laila, ka mea wale ike loea ala mea e hooholo avidity. He aha aʻole ia ke ano o? I ka laloʻo Solomona, a pela avidity Toxoplasma ka mua komo i loko o ke kino. A, nei wehe ano o ka hookaawale ana haʻahaʻaʻo Solomona a me ka kiʻekiʻeʻo Solomona nā mea'aʻaʻa no ka oluolu o ka helu a me ka hoomaopopo ana i ke 'ano o ka maʻiʻaʻai.

Herpes simplex mea hoʻomaʻi

Ka hapanui o kanaka ma ka honua e iho mailoko o ia me ka herpes simplex mea hoʻomaʻi. Kekahi kanaka i ka maʻi i loko o ia lŘlŘ ka latent palapala, akā, e malama loa symptoms, a hiki ina ka mea, e nīnūnē. Eia hou, aia nō kekahi mau hihia me pehea e ho oholo i ka avidity o herpes. He aha ka mea, 'o ia hoʻi ma ka hana? Kēia mea hoʻomaʻi Ua wehewehe aku ma atypical lāʻau lapaʻau kino, ka mea e ia i loko o ke kino no ke ola, e haawi ana wahahee-maikaʻi a me ka wahahee-io hopena. Wahahee maikaʻi 'ole i paa i ka wa a na immunoglobulins mea,ʻaʻole i hanaʻia ai i loko o ka lāʻau lapaʻau ma ka kumumea dala. Wahahee-maikaʻi hualoaʻa ana ma muli o ka ua hooloihi ai hoʻolahaʻia nā mea'aʻaʻa nānā 'ole o ka maʻiʻaʻai.

Eia hou, ka mea, i kekahi keʻa-kū'ē antigens i mimic pehea histocompatibility antigens o maʻamau kino nā'aʻaʻa, a me nā ano o ka herpes mea hoʻomaʻi. Kekahi wahahee maikaʻi reactions e hooponoponoia ia mea, ma ka haumāna maʻiʻaʻai me na kanaka immunodeficiency mea hoʻomaʻi.

cytomegalovirus maʻiʻaʻai

Kēia mea hoʻomaʻi o ka loa e like me ka culprit no abortion i loko o kakahiaka hāpai keiki. Ka pilikia o ka maʻiʻaʻai hilinaʻi nui ma luna o ka nui o nā mea'aʻaʻa i loko o ka makuahine, i ka manawa o ka hapai ana. Inā ka loiloi mua maʻiʻaʻai ana i loko o ka trimester mua, i ka manawa o ka maʻiʻaʻai ka 50 pakeneka.

He aha ke ano o ka mea makemake avidity no CMV? Like i loko o nā mea a pau nā hihia, me ka manao paa o ka Solomona o IgG me IgM maikaʻi naoh i pololei hoʻokūpaʻa a hoole i ke alo o ka iniiaiie CMV maʻiʻaʻai. Eia hou, ka mea e leie aku oe, e pale aku ola a me ka pipiʻi kaʻina hana no ka expectant makuwahine.

Hepatitis C mea hoʻomaʻi

ʻike, o ka hepatitis ma muli o ka hoʻoholo 'kekahi hōʻailona e hoike ana i ke kūpono' ana o ka maʻiʻaʻai kaʻina. Ma keia hihia, IgM hiki i hoʻomaka ai ka hope ma mua ia o IgG, a me ka poʻe me ia. He paakiki e hooholo i ka hoouka kaua ana o ka mai, a me ka manawa o ka iniiaiie maʻiʻaʻai.

Na wale ike loea serological Ka Ikepili mea serokoversiya a IgG avidity ma. He aha aʻole ia ke ano o? Inā ka avidity inideka mea haʻahaʻa, keia mea he pololei hōʻoiaʻiʻo nō o ka iniiaiie maʻiʻaʻai. Ma ka hihia o ka hoomaopopo ana i ke kiʻekiʻe avidity IgG papa nā mea'aʻaʻa hiki, he olelo maʻi hepatitis a E neʻe i.