"Gabapentin" a me ka waiʻona: hōʻike manaʻo. "Gabapentin": aʻo no ka hoʻohana 'ana, ahonui e hoike a me na kumu

Mai manawa i ka manawa, Muscle cramps bother nui kanaka. Eia naʻe, mau kanaka manaʻo e pili ana i ke kumu o ia Hawaii nui e ala mai oe.

E like me ke akamai, ke kāʻili 'hiki e okoa: generalized (tonic, clonic, tonic-clonic a me ka myoclonic) a me ka hapa (hemahema hoi a me ka eiiieaena). he lāʻau hoʻohana 'ia no ka hana kāʻili' hope me "Gabapentin". Na Ke Kumu no ka hoʻohana, hōʻike manaʻo a me contraindications o ka lāʻau, e ia ke hōʻike i ka apana uuku na hope.

Ia lakou e ike koke e kaulana ia, no ka hapa ke kāʻili 'ana wehewehe aku ma ka wa e kaawale aku o ke poho o ka ike paka i. Oia pohihihi keia ano. Ka mea, eʻikeʻia clonic kāʻili 'ano ke komo pū i ka Muscle lima, na wawae a me ka maka.

Haku mele 'ana, hōʻikeʻano,'ōpala huahana a me kona haku mele' ana

kuai lilo aku la medicament "Gabapentin" Ma ka palapala? E hoike hōʻike i kēia lapaau hiki ke kuai ma ka hale kūʻai lāʻau lapaʻau i loko o ka palapala o ka hana gelatin capsules ma keʻokeʻo. Lākou maʻiʻo mea he keʻokeʻo paha yellowish he lepo lā lāʻau.

Kaʻeleu 'Oponopono o keia Agena mea gabapentin. Nō hoʻi, e nā ka hou waiwai i loko o ka palapala o ka paʻakai carboxymethyl pia, kalipuna stearate a me ka microcrystalline kelulose. Like no na capsules, ka mea, iloko gelatin a me ka titanium'okikene lua.

Ma ka AEeAaOA kuai lilo aku la i ka lāʻau "Gabapentin"? Consumer hōʻike manaʻo e olelo aku ia ma luna o nā shelves o keʻena kūʻai lāʻau lapaʻau i ka lāʻau hiki ke loaʻa ma ka pepa he huihui, a i waiho kekahi polymeric capsules la e hiki ai 'ole contour o ka halepaahao.

I ka rula o ka hana ana i ka lāʻau '

Pehea ke ano o ka lāʻau "Gabapentin"? Na Ke Kumu (hōʻike manaʻo o ka lapaʻauʻia e hooku iho la ia ma ka hopena o ka 'atikala) ai ia mau moʻolelo i ka lāʻau i loko o kona' ole ka mea i like loa me ka neurotransmitter gamma-aminobutyricʻakika (me Gaba no pōkole). Naʻe, ka mea e e hoʻomaopopo i ka loina o ka hana a ka fundamentally okoa mai 'ē ai' e pāʻani aku me Gaba-receptors (e laʻa me, valproate, barbiturates, benzodiazepines, me Gaba transaminase nā mea kūpale, me Gaba reuptake nā mea kūpale, me Gaba agonists a me prodrugs o Gaba).

Nānā akula au i ka lāʻau 'ʻAʻohe me Gaba-ana i ka waiwai, a aole i pili i ka hopu a me ka pūnao o Gaba. Research kilo kaua nō i hōʻike i ka hana 'Oponopono o ka agena ma ka paa ana i α2-δ-subunit o ke anakahi uila-e kaukaʻi kalipuna auwai a, me ke kahaha nui hoemi i ke kahe o ke kalipuna Ion, i pāʻani i keʻano nui kūlana ma ka hoouka kaua o neuropathic eha.

Features anticonvulsant lāʻau

He aha nā waiwai i uluhia e ka lāʻau "Gabapentin"? Reviews o nā kauka e olelo aku i ka mea i loa mana no neuropathicʻeha. Kēia lāʻau ho'ēmi i kā glutamate-e kaukaʻi neuronal make, e māhuahua me Gaba hoʻololi kemikala, e like me ke kaʻina hana o ka suppression o neurotransmitter kalaʻana aku a me ka monoamine pūʻulu.

Mākou hiki ole ke olelo ia ma clinically pili nā hoʻohui like o ka lāʻau "Gabapentin" aole e hoopaa i ka receptors o'ē aʻe ai '(a neurotransmitters), me Saula receptors a me GABAB, a me ka glutamate, benzodiazepine receptors, glycine, a me N-meto-D- aspartate.

Haʻalele "Carbamazepine" a me ka "phenytoin", noʻonoʻo ka medicament aʻole e pāʻani aku me ka paʻakai kaha. E hoomakaukau ai "gabapentin" hapa 'ia' attenuates i ka hopena o ka glutamate mea loaʻa agonist e like me N-meto-D-aspartate. Eia hoʻi, ia me ka nui loa ho'ēmi i kā ke kala o ka monoamine neurotransmitters.

Ke kinetic waiwai o ka lāʻau

He aha nō ka hoʻomaopop 'ana i kinetic kiko'î capsules "Gabapentin"? Hoike e ole e hiki ke pane i kēia nīnau. E loaʻa ia, oe e i e huli i ka hoao ana i ka 'Oihana a puni iho la ka olelo ao.

E like me ka mea hope, o ka bioavailability o ka olelo mai ai 'i ole hapaʻauhau i ka laʻau heluna hookama. A hiki i ka nui o ka lāʻau ua hoemiia.

Ma ka loaʻa 'ka medicament i loko o kona i kā mākou wai koko lehulehu malamaia ma hope o 3 h. Ke loa bioavailability o ka lāʻau i loko o capsules mea o ka hola 60%. Food, me he loa momona, i ole ia ma luna o nā kinetics o ka lāʻau.

Withdrawal "Gabapentin" o ka hoʻomanawanuiʻana koko ua lawe mai ma ka laina kükohu. hapa-ola manawa mea kuokoa o ka mahele lāʻau a me ka mea o ka hola 5-7 hola.

Ke kinetic waiwai o ka lāʻau, aole ia e hoʻololi i ka wā i ua noi pinepine ae la oia. I ka lehulehu o ka lāʻau i loko o ke koko hiki ke wānana ma muli o ka hopena o kona hookahi mahele lāʻau.

Ka medicament "Gabapentin" kūpono kou, aole e hoopaa i ka wai koko nā polokina (emi o 3%). Ua Ua 'ia i loko o ua hoʻololiʻia ano ma nā puʻupaʻa.

Metabolize ka lapaʻauʻia ua i hooleiiaʻi mawaho. Eia hoʻi, ka mea, 'aʻole i induce hepatic oxidative nā'ūhū, a i' ole ma o ka pūnao o'ē aʻe ai '.

I kaʻae o ka agena, mai ke koko emi ma mua kanaka a me nā mea maʻi me hihia hoʻi hakuʻala kuleana pili i.

E hoomakaukau ai "gabapentin" ua wehe 'ia mai ke kino ma ka hemodialysis.

Nāʻikepili e loaa ka lapaʻauʻia

Ma ka maʻi mākou i kona hoomaopopo ana, ua maopopo ka hoʻokō lāʻau? He aha kanaka i ka i ana e pili ana i kēia manaʻo?

"Gabapentin" maikaʻi hoike mai ai ia ia iho i loko:

• neuropathic eha i ka makua e hoomanawanui i (18 makahiki a 'oi);
• monotherapy a like me ka mea manuahi lāʻau no ka iapaau ana o ka helehelena kāʻili 'ana, pu ma haumāna generalization i loko o nā mākua a me nā adolescents mai ka 12 makahiki o ka makahiki.

Contraindications i ka loaa ana ka lapaʻauʻia

He aha e na contraindications lāʻau i "Gabapentin"? Reviews o ka palapala noi hōʻike i ia mea he hopena maikaʻi ia ma luna o ke kino, ina o ka ka lapaʻauʻia ua, ua maliuia mai ia ma:

• hypersensitivity i kekahi o ka waiwai;
• ka helehelena hopu ma lalo o ka makahiki o 12 makahiki.

Special malama o ka mea i hoakaka ia no ka hakuʻala ole.

Pehea e lawe au i ka ka lapaʻauʻia "Gabapentin"?

Reviews (neuralgia keia laau kōkua loa maikai) moku'āina i ka lāʻau 'ai e haawiia mai wale ma ka hoao ana i ka Kauka, ma hope o ka pololeiʻike.

Gelatin capsules ia hōʻike waha ma ka moni 'ia a pau, ma ko lakou ano. Ka lāʻau 'E e hoʻopau nānā' ole o ka palaoa, holoi iho la ia me ka nui wai. Inā 'oe pono e emi i ka laʻau heluna o ka lapaʻauʻia, e ana ai e puku i kona mea like, a laila, i kēia E e hana i nā luna o ka hebedoma.

Lapaʻau o neuropathic eha i loko o nā mākua

Like i loko o kēia moku'āina hana, noonoo iho la ka lapaʻauʻia? He aha kanaka i ka i ana e pili ana i 'inikua hōʻike manaʻo? "Gabapentin" loa ka pono hoike mai ai ia ia iho, no ka neuropathicʻeha. Ma ka hana maikaʻi i ia kūlana i ka loiloi mua kela la i keia mahele lāʻau e e 900 mg. I aku la o ka nui ua maheleia i ekolu apana. Inā koi 'ia, i ka mahele lāʻau ua i nā mahuahua i kekahi i kā mākou (a laila, i ka 3600 mg no ka lā).

ka helehelena kāʻili 'ana

Pehea e au e lawe i ka ka lapaʻauʻia "gabapentin" i loko o kēia maʻi? Reviews Ua hoike ia i ka mea paahana hiki ke hāʻawi ole wale i nā mākua, akā, nā pōkiʻi mai ka 12 makahiki.

ʻO ka hoʻokō mahele lāʻau no ka hapa ke kāʻili 'ana ia mea, noonoo 900-2400 mg no ka lā. Iapaau ana o keia maʻi hiki hoʻomaka me 300 mg o ka lāʻau 'ekolu mau manawa o ka lā. A laila e e hookomo hou mai la mahele lāʻau i 900 mg, a me ka nui, a i ka 2400 mg no lā (māheleʻia i loko o ekolu like nā māhele).

Ka manawa wā mawaena ma waena o nā māhele o ka lāʻau ma kona Triple? Eaia e ole e oi aku mamua o 12 hola (e pale i ka resumption o ke kāʻili 'ana).

ʻaoʻao waiwai

He aha adverse reactions kānāwai i loko o nā mea maʻi loaa anticonvulsant? He aha kanaka i ka i ana e pili ana i keia consumer nāʻana? "Gabapentin" i loko o ka iapaau ana o neuropathicʻeha hiki i:

• asthenia, accidental poino, o ka eha ana o kekahi IIeEeAIEUAA, hoʻiʻeha, maʻiʻaʻai, maʻi palū maʻi pale, headache, ke kaupaonaʻana waiwai,ʻike ākea edema;
• gait haunaele, ataxia, amnesia, hypoesthesia, ka hilahila, pōniuniu, hoʻopōʻino noʻonoʻoloi, drowsiness, tremor;
• constipation, flatulence, diarrhea, ka luaʻi, maloo waha, dyspepsia, nausea, abdominal eha;
• ili lapuwale ia;
• pokole o ka hanu, eha loa puʻu;
• amblyopia.

Ma ka iapaau ana o ka helehelena kāʻili 'ana, i ka lāʻau a hiki i ka poʻea pau ma ka nānā aku:

• hoʻi eha, luhi, kuni, headache, mea hoʻomaʻi maʻiʻaʻai,ʻike ākea edema, ke kaupaonaʻana ka waiwai, ka luhi, malaise, lehalehu t edema;
• constipation, kahua niho maʻi, diarrhea, indigestion, mahuahua ikaika loa ka makemake, maloo waha a puu, nausea a me ka luaʻi, abdominalʻeha, bloating, anorexia, gingivitis;
• symptom o vasodilation paha hypertension;
• leukopenia, purpura;
• fractures, myalgia a me arthralgia;
• amnesia, ataxia, ka hilahila, incoordination, kaumaha, dysarthria, mea naʻau lability, Kanikani'āʻula, nervousness, nystagmus, drowsiness, 'āno'ē noʻonoʻoloi, tremor, Muscle twitching, pōniuniu, hyperkinesia; waiwai, i mea hoʻonāwaliwali maoli a kaawale o reflexes, uunu nui, paresthesia, me ka manaʻoe hōʻeha;
• abrasions, huehue, ili ka ohane, ili lapuwale ia;
• cough, pharyngitis, rhinitis, pneumonia;
• amblyopia, diplopia, blurred hihiʻo;
• urinary'āpana nā mea palahēhē, impotence.

hihia o ka overdose

He aha i na symptoms o overdose hiki ia mea, olelo mai medicament? He aha e pili ana i keia olelo i ka nāʻana? "Gabapentin" overdose ke kumu papalua hihiʻo, pōniuniu, drowsiness, hoʻopōʻino waha, lethargy a me ka diarrhea.

E hoʻopau i na Hawaii symptomatic Inc, e like me ka luahi holoi opu, a haawi aku la ia ia ho'ā 'charcoal.

Nā mea maʻi me ka loaʻaʻa puʻuwai insufficiency, hemodialysis ua hoike mai.

Uluwehi O "Gabapentin" a me ka waiʻona

Reviews hoʻomalu hōʻike i ka ka hoʻokōʻana o ka ai 'noʻonoʻo pono ka loa kiʻekiʻe. Akā, e mea wale nō i loko o ka hanana i ka wā o kona palapala noi i ka hoʻomanawanui ua pau haalele i ka hoʻohana 'ana o ke kanakaʻona mau nā mea inu.

Inā ka lāʻau e hui me ka waiʻona, i ka hoʻomanawanui i me ka nui loa worsen adverse reactions mai ka Central ko mākou hopohopo'ōnaehana (, nanea ana, ataxia, etc.).

lāʻau hana kūleʻa

Uluwehi O "gabapentin" ma ka neuroscience, hōʻike manaʻo o ka mea i oi ma mua o 'oluʻolu, hiki ke hui ole ia me nā lāʻau.

E like me na kuhikuhi, antacids emi ka bioavailability o ka lāʻau.

Myelotoxicity ai 'hoomahuahua haematotoxicity capsules "Gabapentin".

I ka hui me ka Morphine kona pharmacokinetics ua ole hoʻololi. Naʻe, ka wā e like me ka hoʻohui pū 'ia E e akahele ua hoʻonānā paha adverse naoh o ka'emi ko kahua.

Nānā akula au i medicament hiki e lawe ka poʻe me antiepileptic ai '(e laʻa me, "pentobarbital", "Carbamazepine", "Phenytoin" a me ka valproicʻakika) a me ka moʻolelo contraceptives. Ma keia hihia, ka mea, 'aʻole e hoʻololi i ka kinetics.

kekahi koi

I loko nō o ka mea i ka withdrawal maʻi pale me ka hanana o ka hopu ana ma ka iapaau ana o "gabapentin" i ole ia e kekahi abrupt cessation o ka iapaau ana me ka antiepileptic ai 'i loko o kanaka a me ka helehelena kāʻili' hiki nō hoʻonāukiuki ikaika convulsions.

Nānā akula au i ka lapaʻauʻia mea,ʻaʻole he pono ka mea e hakakä me ka wa e kaawale aku epilepsy.

People ka poe Pono luna 'Inc me Morphine, e nele ka māhuahua mahele lāʻau o "gabapentin". Ma keia hihia, hōʻoia 'ikaika ka mālamaʻana o ke ahonui i ka hooulu ana o ka drowsiness. Ma kona nä lapaau mahele lāʻau e e ponoʻole hoemi.

I ka hui "gabapentin" me nā anticonvulsant ai ' i ua hoike wahahee maikaʻi i nā hualoaʻa ma ka manao paa o ke kumuʻiʻo ma ka mimi hoʻohana ho'āʻo holehole mai ai i Ames N-Multistix SG. Ma keia manao, no ka mea haʻawina waiho aku i ka hoʻohana 'ana i ka hana i ho'ākāka' kimu ano ma sulfosalicylicʻakika.

Reviews 'Oihana a me nā mea kūʻai mai

Ka hapanui o hōʻike manaʻo o nā lapaau a me nā mea maʻi e pili ana i ka "Gabapentin" hoʻomākaukau i maikaʻi. Mau hoike paipai ana i ka lāʻau 'ka pono Makuakane me ka hana. Naʻe, ka wā ka mea, ua hui me ka waiʻona pinepine hoʻomōhala loa adverse reactions ma ka'emi ko kahua.

He mea hiki ole keia i ole e hoailona oukou i ka mea i ka abrupt withdrawal o ka lāʻau hiki i nā mea maʻi blunted ike paka, lethargy a me ka inoino naʻau i loko.

He nui na kanaka i kaulana i kaʻai ana o keia mea ka mea, i ke kaumaha a me ka suicidal manao. No hoi, ka lapaʻauʻia pinepine kumu o ka hooulu ana o ka huʻi pancreatitis.

Poe akamai i paipai aku i ka lāʻau lapaʻau "Gabapentin" ma lalo o ka hooponopono ana o ke kauka nana e e hiki ke koke hoʻomaʻa i ka pākōlea regimen like pono wale.