Langerhans aeea histiocytosis: 'ehaʻeha ka a me ka iapaau ana

Langerhans keena - keʻokeʻo koko aeee i kekahi hapa o ka'ōnaehana paleʻea'ōnaehana, a me ka maʻamau kumu hula nui i kūlana i loko o ka pale 'ana i ke kino e kū'ē nā mea hoʻomaʻi, koʻohune a me nā palapala microorganisms. Ka mea i loaʻa i loko o kaʻili, lymph aka wahi, spleen, iwi ka lolo a me ka ia maʻiʻaʻai.

He aha ka Langerhans aeea histiocytosis?

Ma keia mai, i ike ia ma mua me histiocytosis X, Langerhan keena olalo e proliferate ma pathological pālākiō. Ma kahi o ke kino hoʻomalu, nui nā hoʻohui like o kēia mau keena lakou aloha ia i ka pono o nā'aʻaʻa a hiki luku aku ia lakou. Loa pinepine e ae mai i ka iwi, a me ka ia maʻiʻaʻai akepaʻa. Oiai keia aeea ka hoʻonuiʻana i nui i like me ka maʻi 'aʻai, loa noiʻi mai i manaoio histiocytosis X ke ano o ka maʻi' aʻai. I ka papa kuhikuhiE differentiating hiʻona i loko o kēia pōʻaiapili, ke hoʻomaopopo iho i ka maʻamau 'ole o keʻano pākīkē keena, a me ka wale pilikia o kā lākou ulu hōʻeleu i. Currently, Langerhans aeea histiocytosis (i loko o na keiki, ia e ke kaulana, ka mea i oi, he pono ole ma mua i loko o nā mākua) ua 'ike mai o ka'ōnaehana paleʻea'ōnaehana, hiki ia'ōnaehana paleʻea keena mahuahua hoi koke, a i li nui a me ka lilo nui i ka puni'aʻaʻa.

Kēia maʻi mea hiki ke hoʻomōhala i loko o kekahi hapa o ke kino, a ma kekahi hui. Ua hiki nō i hoʻomaka ai i loko o kekahi mauʻokoʻa i nā wahi ka poʻe. Ma ka hapanui o hoopii, nae, o ka pathology e loli ai mau nenoai o ke kino wale i loko o na keiki ma lalo o nā makahiki o ka makahiki. i loaʻa mehameha lesions i loko o nā keiki a me nā mākua.

kumu

He nō ike ole no ke aha la he mea e like me he pathology. Eia naʻe, ua hoʻomōhalaʻepekema ma ka hōʻoia o ka kēia kuhiakau: loa paha i kekahi ano o ke ano o mea i loko o ka papa, o hiki mai kekahi mea hoʻomaʻi maʻiʻaʻai e haawi impetus i ke kūpono 'ana o kāna hana ma o na la excessively, pili naoh ma ka'ōnaehana paleʻea nenoaiu. Naʻe, i ka pololei kumu o ka maʻi ma ka manawa malalo i ka 'ike. Kekahi ike kilo mea hana hoihoi ': kokoke nā mea maʻi a pau me IIeEeAIEUIeXAIIUE maʻi i loko o ka akemāmā e hana' ole ma mua uahi paka. Aka hoi, a hiki ina ka nui hoi o ka makana o ka uwahi ana i loko o ke kaiāulu ka loa pohihihi keia Langerhans histiocytosis. Nā kumu pū i ka hoʻohana 'ana o ka pakalōlō i loko o ka papa inoa o ka kamepiula kumumea e like ole, no ka mea, he pinepine ka maʻi, a aole i pili i nā maʻiʻaʻai. Ka loa paha kuhiakau mea i ka hopena maikaʻi 'ole o ka momoku hoʻomaopopo ka hoʻonuiʻana o Langerhans aeee i loko o nā mea maʻi me ka genetically paa ke nānā predisposition ia ia. E like me kekahi kumumanaʻo, ke kumu kumu o ka maʻi moe i loko o ka innate'ōnaehana paleʻea'ōnaehana kāna hana.

E lulu aku hoi

Noʻonoʻo i ka maʻi mea pohihihi keia, a ia lŘlŘ i loko o kahi o kekahi hihia i 250 tausani keiki a me kekahi hihia no miliona makua. ʻOiai ka symptoms kānāwai i kekahi makahiki, ia loa pinepine diagnosed i loko o nā keiki a me nā adolescents, a me ka 70% o ka hihia ana i loko o nä histiocytosis makahiki i ka 17 makahiki. Ma ka muli makahiki pae ana o nā mea maʻi, 'ikepili helu ala ma ka makahiki, mai kekahi i ekolu makahiki.

ano o ka maʻi

Langerhans aeea histiocytosis i loko o nā keiki a me nā mākua komo ai 3ʻano a mua noʻonoʻo pono kuokoa pathologies. Ua eosinophilic granuloma, Henda maʻi - Shyullera - Christian maʻi a me Letterer - Siwa.

symptoms

I ka maʻi ke hoike mai ai ia ia iho ma ka mea kēia mau hiʻona:

• paakiki ka eha, a me ka haanou ana i loko o ka iwi, o ka oi aku i loko o kou lima a me ka wāwae;
• he mau māwae, i loko o ka iwi, o ka oi aku ina mea ua ole ma mua ma kekahi 'aoʻao pilikino eha ai ma mua ma ka malamalama, hōʻemi iki loa;
• Nui i wāhiʻia ma waena o kona mau niho i ka hihia ma ka Langerhans aeea histiocytosis i loko o na keiki ua palahalaha ae ai i na iwi o ka iwi;
• pepeiao maʻiʻaʻai a pepeiao hookuuia, ina o ka maʻi i loli i nā iwi o ka puniu wale no kokoke i ka pepeiao;
• ili poʻe noʻonoʻoʻole preferentially IIeEeAIEUIeXAIIUE ma na lākou kīkala a me ka ili poo;
• lymphadenopathy;
• ake hoʻonui, a ma kekahi mau hihia i ke ukali ma na hoailona o ka hui, dysfunction (yellowing o ka ili a me ka maka (jaundice) ole pathological hoʻomāhuahua o ka loli ma ka abdomen - ascites);
• exophthalmos - ka pohupani hale o ka'ōnohi a poʻopoʻo ka mua manawa histiocytosis me ka IIeEeAIEUAA o ka maka;
• pokole o ka hanu a me ka cough, akemāmā me lesions;
• kali ka ulu a me ka excessive urination ma muli o ke hormonal imbalance.

Emi na symptoms o ka maʻi i:

• kuni;
• ke kaupaona poho;
• irritability;
• i ka hikiʻole, e hoopaa i ke kaumaha a me ka malama i ke kino i loko o shape.

lapaʻau '

No ka Langerhans aeea histiocytosis (Photo hoike ana mai o keia maʻi mea,ʻaʻole he nani maka) Ua pohihihi keia, a ua olelo ia ma symptoms i mea oluolu kuhihewa no na symptoms o na mea he nui 'ē aʻe ka maʻi,ʻike pinepine mea eiiieaena, a lawe manawa. I mea no ke aha la ke kauka e ninau pili i nā maʻi paha e ninau aku oe i ka oi ka pono differentiate i ka manao histiocytosis.

Ke iniiaiie PalekanaEND_LINK hoʻokolokolo 'ana o ke kino ai ninaninau, ma a ke kauka assesses ka pono ola kino a me ka uku mau noonoo ana i ua mau wahi ma na symptoms o ka maʻi hōʻike. Inā ka hoʻomanawanui inā pilikia ka haumāna eha i loko o ka iwi a me complains o haanou ana i loko o ka iwi, ke kauka i hoakaka ia i ka hae X-kukuna a me ka iwi scintigraphy. X-kukuna hoike fracture hapa i kapaia o lytic lesions, a me ka scintigraphy e hooholo i ka wahi o ka eha ma ka iwi kū kaʻawale UOAAaOON e ola.

Na Huaolelo Me Tomography (HI) ia i loko o ke ao ana o ke kua a me na pelvis i hihia ma ka lapaau hāʻupu i ka mea i loaʻa i eʻekeʻeke o luku hou. I ka symptoms hōʻike o ke akepaa dysfunction, e pono ai ke koko e ho'āʻo ai. Inā he mau hoailona o ka akemāmā poino, a me ka manawa ma ka hoʻomalu ma luna o ke kumu o ka loiloi mua 'inikua ninaninau hāʻupu i Langerhans aeea histiocytosis e hōʻike ia i loko o ka maʻiʻaʻai, i hoakaka ia X-kukuna a Me tomography o ka pahu. HI scan NineManga.com o ka poo i hana i ka Loiloi i ka moku'āina o ka lolo. Ke hou visualizing enehana, Ka Hānai Ā Huhu (positron ea puka tomography) hiki no hoi e maikaʻi kēia.

Inā e manaʻo ai he Langerhans aeea histiocytosis i loko o nā keiki (e nānā kiʻi. Ma ka hoʻomaka o ke 'atikala) biopsy i e pono ai, e like me keia mea me ka wale iaoia e hōʻoia i ka presumptiveʻike. Ma kēia kaʻina hana, i ke kauka e lawe aku oe i ka mea uuku hāpana o'aʻaʻa ai iwi e e? Anoee i loko o ke keʻena hoʻokolohua. Ma ka hapanui o na hihia, ua extracted he hāpana o liluwelo mea mai wahi kahi kauoha IIeEeAIEUIeXAIIUE Langerhans aeea histiocytosis: iwi,ʻili a me ka lymph aka wahi. Koko ho'āʻo ma ke kōkua ike ai i ko ka iwi lolo ua loli.

lōʻihi like

He paʻakikī ke kilokilo pehea koke ka maʻi, a pehea ia e hoike mai ai ia ia. Ma kekahi mau hihia, o ka pathology nalo ana iho, a 'aʻole i koi' inikua 'uao. Kēia ia lŘlŘ ka wā o ka 'aʻe' ua IIeEeAIEUIeXAIIUE ma kekahi wahi (ma ka iwi a me ka ili), a me ka wā i puhi paka me ka akemāmā poho pohaku e hoopau uahi paka. Naʻe, ka mea i hana i ka maʻi mea ona; make hiki ke wānana i loko o ia mau hihia wā hoʻomāhuahua o abnormally proliferating aeee e hoomaau i ka ia manawa he nui o okoa nā loko a me ke kino wahi. Ka moku'āina o ke ola ana o ka puhi paka hoʻomaka i ka hoʻoikaika 'ana wale nō ka wā quitting.

Kāohi

Mai ke kumu o ka 'aʻe' e waiho ana no he mea pohihihi, no laila, hiki,ʻaʻole nō he pono ka Kāohi ana. Eia naʻe, i haawiia mai ia e loli ana i ka ia maʻiʻaʻai wale ma kânaka e puhi he kikaleki, e haawi ana i ka 'ino hiki ke ike me ka kāohi histiocytosis IIeEeAIEUIeXAIIUE i loko o ka ia maʻiʻaʻai.

lapaʻau

Inā ke hoʻomanawanui i kaʻike, hookupaa iho la ia o "histiocytosis o Langerhans aeee", ka iapaau ana, e hilinaʻi ma ka oolea a me ka loa o ka nahā.

Inā abnormality ua 'akomi i loko o hoʻokahi wale nenoaiu o ke kino, i ke kauka e koi' ia corticosteroids, ma ka pau "Prednisolone". Eia kekahi, e hiki i ke undergo i ka papa o ka chemotherapy. Eia hou, i ka hoʻohuli ai i nā wahi o ka iwi wehe 'ia ma ka curettage - hamoʻia. Inā pathologically accrescent aeee i kia ma kekahi wahi o ka ili, ka maʻi hiki ke ola ma ka uhi ana i ka hoʻohuli ai i nā 'āpana naikokene makeke - chemotherapy Agena. Ua Ua hoi hoʻohana "Methotrexate". Radiotherapy ua lawelawe ma ka hihia ma ka iwi maʻi (e laʻa me, i loko o ka luna wāwae 'ole i loko o ka spine) alakai aku ai i ka mea hoʻonāwaliwali maoli nō o ka pau iwi apana nahaha. Musculo-eaʻoki kino ma ka spine - kuʻi nukeliu - ua paipaiʻia ka wā iwi instability i loko o ka cervical māhele 'āina.

Generalized (systemic) Langerhans aeea histiocytosis - he nui oi nui ke ano. No ka hana maikaʻiʻole o ka chemotherapy hiki ke hoopili hoi, nae, kona laulā ua nunui hoemi like i ka Inc me hookahi lesion. ʻOiai ua poe akamai i hookolokolo aku la ia i ka laulā o na mea he nui ai ', e pono ai' inikua lapaʻau iʻaʻole naʻe, ua loaʻa. Aka hoi, ma ka mea e kanaka hoʻoponopono i ke kūpono 'ana o ka maʻi i kou kauka e koi' ia kekahi o nā kēia mau mea:

• "Vinblastine";
• "Etoposide";
• "Mercaptopurine";
• "Cladribine";
• "Cytarabine";
• "Methotrexate".

Ma kekahi mau hihia, kauka waiho aku ake transplantation, iwi ka lolo, a me akemāmā, akā, i waena o nā kānakaʻimi noiʻi kona manaʻo ma ma ka e pono ai ke hui, transplantation i loko o nā mea maʻi me ka histiocytosis iʻaʻole naʻe, ua hiki.

I ka wa e ike i kekahi kauka?

E hōʻoia i ka leka uila i kou iniiaiie malama pediatrician ina e manao Langerhans aeea histiocytosis i loko o nā keiki. Ocular symptoms, ka eha, a haanou ana i loko o ka iwi, maʻi ili rashes i na symptoms o kēia ke nānā maʻi. Inā kekahi o kēia mau symptoms a pathology i loko o nā mākua e nīnau aku i ke kauka.