"Azithromycin" no na keiki: manual, hōʻike manaʻo

I Ina o ka huikau nā mea palahēhē i ole lawelawe hiki penicillin ma muli antibiotics, kauka i hoakaka ia "azithromycin". No na keiki (kuhi no ka hoʻohana pili ia i ka mea,) i ka lāʻau i ka loa ikaika hookoia, ma kekahi hihia, hiki loko,ʻaʻole i maopopo i hana meaola, no laila, lawe ia pono palena iki nā māhele.

Release palapala a me ka haku mele 'ana

Hoʻomanaʻo ninoieo oʻeleu waiwai a me kākoʻo excipients azithromycin ana i haawi aku ai nā loina ano papa. No hoi i ke aloha i kēia mau waiwai i ke kemu maikaʻi lāʻau.

Aie i ka palahalaha pae antibiotic hana likeʻole ano o ke kalaʻana o ka lāʻau 'ia i loko o kēia pharmacology:

• Hard gelatine capsules me ka uliuli poʻi kino a me ka uliuli, ma loko i mea keʻokeʻo paha haikea yellow he lepo lā ( 'ole i ka olelo hoopomaikai nui). I ka wa e holo ikaika aku nei i ka anaʻe. Nā capsules i hookomoia ma ka hou ana i kaʻeleu 'Oponopono, microcrystalline kelulose, paʻakai lauryl sulufahate a me ka makanekiuma stearate.
• "Azithromycin" (125) kuhi no ka hoʻohana na keiki wehewehe like papa ho film kapa komo iā ia i loko o uliuli, he hoʻopoepoe kinona, biconcave. Ma ka kekahi lima ka mea, i ka engraving "PLIVA", ma ka 'ē aʻe - "125". Inā 'oe e wāwahi, e hiki ke ike ia ma ka huli ana o keʻokeʻo Akala. Ua ninoieo o na kēia mau adjuvants: anhydrous kalipuna hydrogen posapahate, hypromellose, ke kulina pia, microcrystalline kelulose, pregelatinized pia, paʻakai lauryl sulufahate a me ka makanekiuma stearate.
• Uluwehi O "Azithromycin" no na keiki ka ike ma ka noi ia kekahi i ke ano o ka wehe ', no laila, keʻena kūʻai lāʻau lapaʻau ke kuai i kekahi kūikawā pauka no kona makaukau me ka kamako iki a maiʻa hohono.

Ke kumu o ka antibiotic, piʻi pū ke kaumaha ma muli o ka maʻiʻo oʻeleu waiwai.

pharmacological ano

"Azithromycin" pili ia i ka laulā-pae antibiotics. I ka kiʻekiʻe nā hoʻohui like i loko o ka pulakaumaka o ka li nui ia lŘlŘ ka make ana o microorganisms.

Most ikepili koʻikoʻi i ka lāʻau gram-maikaʻi cocci: Streptococcus pneumoniae, Streptococcus pūʻulu CF a me G, Staphylococcus aureus, St. Pyogenes, St. Viridans, St. agalactiae; Gram-io koʻohune: Moraxella catarrhalis, H. Ducrei, Haemophilus influenzae, Legionella pneumophila, Bordetella pertussis, Neisseria gonorrhoeae, B. Parapertussis, Gardnerella vaginalis a me Campylobacter jejuni; anaerobic meaola: Chlamydia trachomatis, Bacteroides bivius, Ureaplasma urealyticum, Peptostreptococcus spp, Clostridium perfringens, Borrelia burgdoferi, Treponema pallidum, a me Mycoplasma pneumoniae. Gram-maikaʻi koʻohune hoʻopale i ka erythromycin, he antibiotic ua hoohuliia i ka AEeOEXAaI ano.

Pharmacokinetics

"Azithromycin" no na keiki (kuhi no ka pili hoʻohana no ka mea,) ua hoʻomaka koke ke kemu, mai ka gastrointestinal'āpana ma muli o ka ia'ku iʻakika meakino a me ka lipophilicity. Hoʻomaka koke haawi ma ke kino. Hoopuni ka mea komo ole wale i loko o ka naehana'āpana,ʻaeʻae'aʻaʻa a me ka ili, akā, no hoi i na nā loko o ka urogenital'āpana. E like me ka hopena, he haʻahaʻa ka paa o ka azithromycin a me ka lāʻau lapaʻau nā polokina, anal akamai i loko o eukaryotic keena a me ka lehulehu ma ka meakino me ka haʻahaʻa pH,? Aneie lysosomes mahuahua lōʻihi like hapa-ola a me ka lehulehu i loko o nā'aʻaʻa.

A pau i kēia e hoʻoholo i ka mea kiʻekiʻe loa ka leo o ka o ka makana (31.1 nā lika no kg) a me ka kiʻekiʻe wai kokoʻae. No ka make ana o intracellular pathogens o ka huakaʻi nā mea i ka hiki i ka "Azithromycin" loaa 'ana i loko o ka lysosomes.

Manawa phagocytes lāʻau i loaʻa i ka paena o ka maʻiʻaʻai, kahi ia i hookuu ia ma ke kaʻina hana o ka phagocytosis. Mahope o 12-72 hola o ka lawe ana ma ka pulakaumaka o ka li nui ua loaʻa e ka lehulehu kiʻekiʻe o ka lāʻau, a me ka nui loa o luna ma mua o ka palena iki inhibitory lehulehu no ka maʻiʻaʻai o pathogens.

E like me ua oleloia, hapa-ola loa kaʻina, no laila, no kekahi laʻana, e noi mai ana 60 i ka 76 hola i wehe mai fabrics. Bactericidal lehulehu o ka lāʻau ua waiho waho ma kahua o ka li nui no 5-7 lā ma hope o ka hope mahele lāʻau, no laila, he mea hiki ke hoʻohana i ka hookahi antibiotic i loko o ka lā, i ka papa o ka iapaau ana mea i oi ma mua o ka hebedoma.

Hōʻike 'ia ka "Azithromycin" puleʻAmelika, ma ka bile, a me wale i ka meaʻuʻuku hapa - ka wā mimi.

Nāʻikepili no ke komo

"Azithromycin" kauoha no ka hoʻohana ana i na keiki i hooluoluia mai ai e koho ma infectious a me ka hoʻoʻino maʻi, a i triggered e koʻohune susceptible i ka azithromycin. Na maʻi nā: pneumonia, bronchitis, sinusitis, pharyngitis,ʻaeʻae'aʻaʻa a me ka ili nā mea palahēhē, tonsillitis, otitis Media, Lyme maʻi a me ka urethritis. No kēia pneumonia pediatricians kamaʻilioʻana i koke i hoakaka ia antibiotics, a hiki ole i ka hopena o ka X-Ray ninaninau. Iapaau ana o keia maʻi, e hoomaka i ka maikai manawa, ai ole oe e maka i ka loa pōʻino hopena. Ke antibiotic i loko o ia ka hihia ua koho e lawe i ka mooolelo o ka symptoms a pau, ka mea e hoʻopiʻi ana i pathogen, a me ka lapaʻau kiʻi like me ka a pau. Ma ka hoomaopopo ana i ka meaola e kauoha ana i ka maʻiʻaʻai, ua laweʻia ka makahiki o ke keiki i loko o mooolelo. Inā pneumonia ua mahuʻi mua i loko o ke keiki elemakule 1 hiki i 6 mahina, laila. loa paha, ka Agena - o Staphylococcus aureus, mai kekahi makahiki a hiki i na makahiki eono - Streptococcus pneumoniae. Me nā 'ano o nā koʻohune ka pono kaua "Azithromycin".

Dosing

Ka iapaau ana regimen e hilinaʻi ma luna o ka maʻi, akā, i ka huina o na mahele lāʻau e e mālama 'ia. Ke Kauka ke koi 'ia i ka lāʻau "Azithromycin" na keiki. Na Ke Kumu no ka hoʻohana 'ae i na papa, e lawe wale nō nā mākua no ka mea, aia no iloko olaila 250 a hiki i 500 mg oʻeleu waiwai, a me keia dala he pōpilikia ma luna o ka nuipa aʻano nui. Ka mea i papa e e ale a pau, e ole? Aeiiaiaoaony e hahi ai kui a nolaila no laila, hiki ole malama i ka paipai laʻau heluna o ka hoʻokahi-manawa hoʻohana (10 mg / kg). Ia mea no ia mea, e nā pōkiʻi like antibacterial Luna lawelawe "Azithromycin" (125). Na Ke Kumu no ka hoʻohana na keiki papa ua papa lawe mai i ka 12 makahiki, ka mea hiki ke auou caiaiai ia me ka malakeke a me ka mai paha.

No ka iapaau ana o ka huʻi hoʻoʻino airway maʻi, otitis, pneumonia waeia hookahi mahele lāʻau lāʻau (10 mg / kg). Uluwehi O "Azithromycin" (125) kuhi no ka hoʻohana na keiki ma ka papa ia kekahi wale ma hope o hiki 14 makahiki o ka makahiki. Iapaau ana Children hana wale nō ka hoʻohana 'ana i ka slurry.

It E e oleloia ia i ka 5 nā huna o ka malakeke "Sumamed" (teaspoon) a me ka 'ē aʻe analogs hoʻomanaʻo i na 125 mg oʻeleu waiwai. Alaila, o ka maʻamau mahele lāʻau no ka mua keiki, he 1-2 tablespoons, ke kaumaha ma muli kaupaona. Iloko o na kēia mau lāʻehā o ka lapaʻau mau, akā, ua hoemi ia i 5 mg / kg i ka ia laʻau heluna. I Ina o loa maʻi mahele lāʻau i ke papalua, akā, ma ka mea o ka kulana, ka hoʻohana 'ana o ka antibiotic mea ana ma lalo o ka hooponopono ana o ka hoʻomalu wale. E hoomakaukau ai "Azithromycin" hiki ke hoʻohana '(125) kuhi no ka hoʻohana no keiki wale nō ma ka hihia o ka loaa ana i kekahi manawa, ai palua i ka laʻau heluna o 30 mg / kg kino ke kaumaha.

Contraindications

Uluwehi O "Azithromycin" no na keiki manual ua papa kaupaona emi mai o elima kilograms. Eia hou, ka mea, ua contraindicated i loko o nā mea maʻi me ka hypersensitivity i na eiiiiiaiou i kakauiaʻi maluna i loko o ka haku mele 'ana i kekahi'ē aʻe macrolide antibiotics. Kēia lāʻau i loko o kekahi hihia pono ole e ia i loko o loa ake a me nā konāhua 'ole.

Overdose a me kaʻaoʻao mau waiwai

No ka makuahine, ka poe i ka hoʻohana 'ana i ka lāʻau "Azithromycin" no na keiki, olelo ao no ka hoʻohana (ahonui e hoike e pili ana i ka hoʻohana' ana o antibiotics hōʻike i loko o kēia mea) e hāʻawi aku i ka papa inoa o kaʻaoʻao loa. Ma ka hapa o ka lymphatic'ōnaehana a me ke koko ho okumu i hoʻomōhala trombotsipenii.

E hoomanawanui i ka hoikeia aggressiveness, hyperactivity, nervousness a me ka uunu nui. Mai ka ua'emi'ōnaehana pōniuniu, convulsions, headache, somnolence, a e maʻule hou ihola nō. Ma pohihihi keia hihia, i ka lāʻau a nā sleeplessness, luhi, paresthesias, i nee pokole o ke ala a me kaʻaiʻana.

Infrequently macrolides (pae o ai ', ke kumu o ka Nine Inch' ole o i nei iluna macrocyclic 14- a 16-Aupuni Lālā a lactone ke komo lima me ka i pili carbohydrate residues), a me ka mea e pili ana i ka "azithromycin" e alakai i ka lohe ana me keia poho. Kākaʻikahi ka, akā nō, uaʻaoʻao hopena o dyspeptic ano a me ka hoike allergic reactions.

"Azithromycin" aʻo ma ka noi e leie keiki e hoʻohana, akā, hiki ke lawe keiki lāʻau i loko o ka palapala o ka wehe 'wale. No ka mua keiki pono a me ka mea hōʻikeʻikeʻuʻuku ke ano o ka antibiotic. Mua ana i ka ka lapaʻauʻia, e pono e kiʻi i ke kauka o ka 'ae a me ka heluhelu i ka AEeAaOA hookomo kuhikuhi akahele.

About overdose e hōʻike diarrhea,? Aiaiiuie poino lohe, nausea a me ka luaʻi. Ina o ka loa i ka paipaiʻia nā māhele pono koke holoi opu, alaila, hoomau aku i ka symptomatic Inc.

Cautions

Ka hoʻohana o "Azithromycin" i hāpai keiki ka loa undesirable, akā, pono ina i ole, e hana ia, e kōkua i ka wahine (lāʻau kanawai ma fetal kūpono 'ana ma ka 100% i ole, ua aʻo). Ke lactation au wā hoʻohana i ka manawa o ka antibiotic lapaʻau, e alalai mai breastfeeding.

Children ma lalo o 12 makahiki ka maikaʻi, e koho i ka Analog "Azithromycin".

Inu waiʻona aʻole e pili mai i ka hana o ka lāʻau, nae ua i huiʻia kona hoʻohana no kekahi maʻi. No laila, o ka nui o ka lukuʻia ‰ ia ua? Aeiiaiaoaony e emi i ka i kā mākou, a hiki maikaʻi, e haawi mai ma ka iapaau ana loa.

lāʻau hana kūleʻa

Ma ka loaʻa 'o ka "Azithromycin" me ka antacids i pihaʻi me kalipuna, makanekiuma a me ka Aluminum, ka mea,' aʻole hoʻi ke omo o ka antibiotic, nolaila, e pono e malama i ka 2-hora wā mawaena ma waena o nā māhele o kēia mau ai '.

Ka papa likeʻole ma waena o kēia k i nā macrolide antibiotics - i ke kamaʻilio me ka cytochrome nenoaiu. Nolaila, i ka wa ia me "theophylline", "carbamazepine", "Digoxin", "terfenadine" a me ka "triazolam" aole i Ua AaOIeIOUIeXAOAaIN.

Inā ua hoʻohana 'ia ka lāʻau a me "warfarin", ia mea pono ke kanaka hoʻoponopono i ka prothrombin manawa.

Lincosamides emi i ka laulā o ka antibiotic a me ka chloramphenicol a me ka tetracycline hoonuiia.

Nā kūlana a me nā hua'ōlelo

Ke antibiotic E waiho waho ma ka loaa ole ana o na keiki ma ke ana wela i ke 25 degere. Ma ka holopapa ola o ka hoike i loaʻa i ka lāʻau "Azithromycin" (no ka keiki), manual. Ke wehe i hoomakaukauia hiki ke waiho waho no i oi aku mamua o 5 mau lā, no ka lepo ia iho - 2 makahiki, a me nā gula'ā'ī, a capsules - mai i 3 makahiki.

Analogs a me ka manao ana o nā mea maʻi

Ka poe i hoʻohana 'ia ka "Azithromycin" no na keiki (kuhi no i na capsules mea i paipai i ka lawe i na kamalii), haʻalele ka hapanui maikaʻi nāʻana. Ma hope o ka mahele lāʻau mua o ka antibiotic kaʻawale lula 'hou ana, holo pono no hoi.

Ma analogues o ka lāʻau nā "Azitsin", "Zomax," "Sumamed", "Azitral", "Azaks", "Zitroks" a me na mea e ae.