Fibrates - He aha ka mea? I ka haku mele 'ana, hoʻohana, contraindications

Ua ua ikeia ia mea'ōnaehana mānowai koko maʻi nō i waena o ka loa, he pono ole pathologies i loko o ke ao nei. ʻaneʻane kela kūpuna kanaka poino hypertension a me ka angina. He nui i ka mōʻaukala o ka loa i hānau mai, e like me myocardial infarction a me cerebrovascular ulia. He mea a ianoiyuaa a he scientifically maopopo mea i mea'ōnaehana mānowai koko maʻi ua pololei pili i ka dyslipidemia. Kēia kūlana hoʻohuʻu i ka loli i loko o ka maʻiʻo o ka naʻokoko, a momoma nāʻakika i loko o ke koko. E normalize ka lipid koena, e hoomanawanui i hoʻohana statins a me fibrates. Kēia pūʻulu o ai 'i pono i loko o nā mea a pau e hoomanawanui i ka poe i ike i ka mahuahua naʻokoko i loko o ke koko, nānā' ole o ka wahine a me ka makahiki.

Fibrates - He aha ka mea a me ka mea a lākou i hoʻohana

Ua ua ike ia ka iapaau ana o ka atherosclerosis mea i hiki ole i ka pono o statins. Ka mea i koi 'ia i nā mea a pau e hoomanawanui i ka poe i ka welelau o ka obesity, coronary naau maʻi, thrombosis. Ma waho aʻeo ia statins, he mea kekahi pae o ka hoʻomākaukau - fibrates. Lākouʻano papa hana o ka 'ana mea iki okoa. No laila, i kēia mau ai 'i hoakaka ia ma ole' o ia hoʻi nā mea a pau. Ka mea, e fibricʻakika nā mea loaʻa. I ka papa kuhikuhiEʻano papa hana o ka hana - ka iaea o lipid pūnao i loko o ke kino. Fibrates - He aha ka mea a ka mea ka mea, no? Ma ka hoʻohana ana i kēia mau hoʻomākaukau hōʻike he nui ka ho'ēmiʻana i loko o ke koko triglycerides. I ka papa kuhikuhiEʻano papa hana o ka hana ana o fibrates ma ka oiaio i ka mea haʻalele i ka'ūhū - lipoprotein lipase, ma laila piʻi aʻe i ka pūnao o kona kaikea a. Ie lakou aloha ia i ka biochemical keʻano o ka hanaʻana 'ia i loko o ke kino. Ma waho aʻeo ia ka iaea o dyslipidemia, fibrates i'ē aʻe 'ole. Iwaena o lakou - i ke kaua e ku e noa radicals, Anati-hoʻoʻino a me ka tonic kanawai. ka mea, eia no hoi anticoagulants.

nāʻikepili fibrates

Aie i ka mea i mau ai 'i na mea he nui' oluʻolu 'ole, ka mea, i ka nui huahelu o ke noi. I ka papa kuhikuhiE PAaIEN no ko lakou manao mea metabolic maʻi pale. Keia ano mea,ʻaʻole he kuokoa maʻi, akā, ka mea, ua manaoia he nui predisposing ololi no ka hooulu ana o ka mea'ōnaehana mānowai koko pathologies. Nā ana hoʻohālike no ka mea metabolic maʻi pale:

1. Abdominal obesity (pūhaka nui ka hana ma ka 90 knm, a kiekie ae).
2. High naʻokoko i loko o ke koko hōʻike.
3. Hoemi i ka nui o ke kiʻekiʻe nuʻa lipoproteins.
4. Ke kiekie triglycerides a me LDL.

Ma ka hapanui o na hihia, ka metabolic maʻi pale ua hui me ka 'ano 2 mimikō, a ia lŘlŘ ma ka kūpuna. Mau kumumea predispose i ke kūpono 'ana o ke atherosclerosis, oa ka hoʻomāhuahua o lipids i loko o ka vascular paia. Fibrates - He aha ia mea, a no ka mea ka mea, i ka lawelaweia ana? Ma waho aʻeo i ka metabolic maʻi pale, nāʻikepili no ka hoʻohana mea: hereditary ano o ka dyslipidemia, a me ka hypertriglyceridemia. Ka mea, i kekahi hōʻike i nā mea maʻi i ka mōʻaukala o nā mimikō a me gout.

Ma lalo o ka hana hea fibrates i contraindicated

I loko nō o ka mea i fibrates i ka helu o ka pono e like me ka 'ē aʻe ai' lakou ma naʻokoko (statins), ka mea hiki ke hoʻohana 'ole i loko o nā mea a pau nā mea maʻi. E hoʻomanaʻoʻoukou i kēia mau ai 'aloha ia i ka pūnao, no laila, ke hoʻohana' ia pololei pāpā i loko o kekahi mau Hawaii. Fibrates i contraindications i ka hoʻohana 'ana i nā kēia:

1. Hāpai keiki a me ka umauma-e ai ana.
2. ake maʻi. Kēia contraindication aie i ka mea i keia pae ana o ai 'loli i ka pūnao o momoma nāʻakika. I ake cirrhosis a me kanakaʻona mau gepatoze hana ia kino me ka nui loa compromised. No keia kumu, fibrates hiki i na nā mea maʻi loa ka hopena, i ka ake ole.
3. Calculous cholecystitis. Kekahi o na waiwai o ka fibrates mea, e hooikaika lithogenicity,ʻo ia hoʻi, ke kahua o gallstones.
4. Maʻiʻaʻa puʻuwai ole. Fibrates hoomahuahua i ka nui o ka creatinine i loko o ke koko. No laila, ka mea hiki ke aggravate maʻiʻaʻa puʻuwai ole.
5. Kaiapuni E e hoakaka ia fibrates maʻi kūpuna. Lākou hoʻohana mea undesirable no kanaka e loaa ana mai ka maʻi alcoholism.

ʻaoʻao 'ole o nā fibrates

Fibrates - He aha ka mea a me ka mea a lakou iʻaoʻao 'ole? It E e kaulana ia, e like me ka ai ', keia pae o ka ai' ua loa kākaʻikahi ke kumu no ka allergic NaI. Ka mea hiki ia mea, e hoʻohana 'ia ma nā mea maʻi i ka mōʻaukala o nā hives, hay kuni, a no laila, ma luna o. D. Aka hoi, fibrates i ka helu o nāʻaoʻao loa. Ka loa, he pono ole i nausea a me ka luaʻi, flatulence, abdominal distension. Ka mea, ke i pili i ka'emi ko kahua. Ma kekahi mau hihia, i headaches, Kanikani'āʻula a me ka kaumaha. ʻaoʻao 'ole i ia mea, noonoo a me ka loli ma ka biochemical Ka Ikepili o ke koko: a mahuahua nui creatinine, Alt, AST. I ka wa e kaawale aku o ka maʻiʻaʻa puʻuwai maʻi a me ka ake mea e hoʻopōʻino no ka hoʻomanawanui i ka ola.

He aha lapaʻauʻia nā fibrates hui?

I ka lā, aia nō ma kahi o 10 ke ano o keia pae o ka ai '. E fibrate ai 'ioiinyony: "Clofibrate", "bezafibrate", "Gemfibrozil" a me ka "Fenofibrate". Kēlā me kēia no kēia mau hoomakaukau oko a e like me ka helu o kaʻaoʻao 'ole a me ka laʻau heluna. Papa "Clofibrate" i, ua ike no na makahiki, a ua manawa kākaʻikahi i hoʻohana. I loko nō o ka ka hoʻokōʻana kiʻekiʻe, ka mea, pinepine iʻaoʻao 'ole e like me kāna hana o ka digestive'āpana, eha i loko o nāʻiʻo (myositis), noho kiʻekiʻe lithogenic. He emiʻawahia lāʻau "bezafibrate". He ua i like kona mana me a koke excreted mai ke kino. Papa "Gemfibrozil" i paipai no ka hoʻohana 'ana i ka lehulehuʻaoʻao' ole (akā, e emi ma mua i loko o ka palapala noi o medicament "Clofibrate"). Nō hoʻi, ma muli o ia i ka pono no ka lōʻihi-makahiki hoʻohana a me ka kiʻekiʻe nā māhele. Most kēia Luna o keia pae o ka lāʻau "Fenofibrate". Ua loaʻa kiʻekiʻe ka hoʻokōʻana a kokoke iʻaoʻao ole. A eia hoi, ka mea, ua hoakaka i nā mea maʻi me ka gout, no ka mea, ho'ēmi i kā ka nui o uricʻakika.

Fibrates: ao no ka hoʻohana i kēia mau ai '

Pehea pinepine, a ma ka mea dosages e pili mau lapaʻauʻia hilinaʻi nui ma luna o ka 'ano o ko lakou hoomakaukau ana ua kohoia ka hele kauka. More pinepine ma mua,ʻaʻole e pono i kaʻai no ka pili ana o ka mahina (a oi) 2-3 o na papa io o ka lā. Na ka papa kuhikuhiE PAaIEN - Ua metabolic maʻi pale. I na nā mea maʻi pinepine hoakaka fibrates. Hoomakaukau Pono e e hui me ka pono kino a me ka pili ma lalo o ka mana o ke lipid. Papa "Gemfibrozil" ua hoʻohana 'ia 1-2 manawa i ka lā 30 minuke ma muaʻai no kekahi mau mahina. Lākou mau analogues i lapaau "Gevilon" a me ka "Normolit". E hoomakaukau ai "bezafibrate" i loaʻa i loko o na papa o ka 200 mg, a ua laweʻia 2 manawa i ka lā i hoʻokahi malama. I hookomoia mea he mea like - medicament "Retard" i loaʻa ka 400 mg oʻeleu waiwai. Uluwehi O "Fenofibrate" i 2 hoʻokuʻu ano: o na papa io a me nanoparticles. Ka mea, i ka oi pono ka omo a me ka bioavailability noi 1 manawa i ka lā (200 mg) me kekahi mau mahina. Kona analogs - he lapaau "Traykor" a me ka "Lipantil".

Fibrates: lāʻau hana kūleʻa

Mua oe i hoʻomaka i ka hana ai 'i loko o kēia pae, oe e kukakuka pu me kou kauka a me ka paipai aku ia oukou i ka mea a nā laau i hoʻohana. Fibrates hiki ole ke hui me nephrotoxic a me ka hepatotoxic konohiki. Ma kekahi, "Cyclosporin" lāʻau. Ka hoʻohanaʻana i fibrates mea i kupono no ka hoʻomanawanui iki mai ka lalau ana anticoagulant "Warfarin". No hoi, e ole e hui keia pae o ka ai 'a me nā dipolipidemicheskimi Luna (statins). No ka mea maoli i ka likelihood o ka ulu myositis.

Reviews o nā kauka, a hoʻomanawanui iki mai ma fibrate

Ka hapanui o nā mea maʻi ka hoʻohana fibrates aho, i kaulana i ka emi ma ka LDL naʻokoko, triglycerides a me ka naʻokoko. Kauka paipai aku i kēia mau ai 'no nā mea maʻi a pau me ka metabolic maʻi pale, no ka lākou kiʻekiʻe ka hoʻokōʻana a me ka laulā-pae. Ke wale drawback mea he contraindication no ka hoʻohana 'ana o fibrates, i mea pinepine i loaʻa i loko o mua hoʻomanawanui iki mai.